supported by a grant from the Basic Science Research Program through the National Research Foundation(NRF),which is funded by the Korean government(MSIP)(NRF-2020M3E5D9079764)(to KS)。
Neuroinflammation has been identified as a crucial element in several neurological disorders. Glial cells play a critical role in directing neuroinflammation, both in deleterious and beneficial ways.
supported by a Lee Kong Chian School of Medicine Dean’s Postdoctoral Fellowship(021207-00001)from Nanyang Technological University Singapore;a Mistletoe Research Fellowship(022522-00001)from the Momental Foundation USA(to CHL).
Neuronal necroptosis-an emerging form of regulated cell death associated with neuroinflammatory signaling:Alzheimer’s disease(AD)is characterized by the presence of extracellular amyloid-β(Aβ)plaques and intracellu...
funded by Ricerca Finalizzata 2016 RF-2016-02361941;MIUR,-PON“Ricerca e Innovazione”PerMedNet id project ARS01_01226-PROGETTI DI RICERCA DI RILEVANTE INTERESSE NAZIONALE Prot.2017MYJ5TH;312 European Commission’s Horizon 2020 research and innovation program,No.847749。
Brain synapses play a key role in neuronal communication:this“conversation”is at the basis of all brain activities and synaptic dysfunction leads to brain disorders.We study the modulators of this crucial synaptic f...
supported by the National Research Foundation of Korea(NRF-2020R1A2C2007954);the Korea Healthcare Technology R&D(HI21C1795)grants funded by the Korean government
Microglial activation in Alzheimer’s disease(AD):In 1907,Dr.Alois Alzheimer,a Bavarian-born German psychiatrist and neuropathologist,published an article describing the clinical and neuropathological features of an u...
Axonal degeneration is a key pathological feature in many neurological diseases. It often leads to persistent deficits due to the inability of axons to regenerate in the central nervous system. Therefore therapeutic a...
supported by a fellowship(2012-2014)from the Canadian Institutes of Health Research(CIHR)
Chronic pain often accompanies immune-related diseases with an elevated level of IgG immune complex (IgG-IC) in the serum and/or the affected tissues though the underlying mechanisms are largely unknown. Fc gamma re...