MITOCHONDRIAL

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相关机构：北京大学中国科学院中国人民解放军总医院中国科学院遗传与发育生物学研究所更多>>
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A pair of transporters controls mitochondrial Zn^(2+) levels to maintain mitochondrial homeostasis被引量：3
《Protein & Cell》2022年第3期180-202,共23页Tengfei Ma Liyuan Zhao Jie Zhang Ruofeng Tang Xin Wang Nan Liu Qian Zhang Fengyang Wang Meijiao Li Qian Shan Yang Yang Qiuyuan Yin Limei Yang Qiwen Gan Chonglin Yang 
This work was supported by grants from the National Science Foundation of China(91954204 and 31730053);the National Basic Research Program of China(2017YFA0503403);Yunnan Province Science and Technology Department(#202001BB050077 and#202105AB160003).
Zn^(2+)is required for the activity of many mitochondrial proteins,which regulate mitochondrial dynamics,apoptosis and mitophagy.However,it is not understood how the proper mitochondrial Zn^(2+)level is achieved to ma...
关键词：mitochondria Zn^(2+)transporter C.elegans ER-mitochondrial contact development 
Solution structure of the voltage-gated Tim23 channel in complex with a mitochondrial presequence peptide
《Cell Research》2021年第7期821-824,共4页Shu Zhou Maosen Ruan Yunyan Li Jing Yang Suwen Bai Christian Richter Harald Schwalbe Can Xie Bing Shen Junfeng Wang 
supported by the High Magnetic Field Laboratory of Anhui Province;This study was supported by grants from the Ministry of Science and Technology of China(Grant No.,2016YFA0400901);the National Natural Science Foundation of China(Grant No.,U1632274);Hefei Science Center of Chinese Academy of Sciences(Grant No.,2020HSC-CIP011);by iNEXT-Discovery,project number 871037,funded by the Horizon 2020 program of the European Commission.
Dear Editor,Most mitochondrial proteins are synthesized in the cytosol and transported into various mitochondrial subcompartments in a process that is mediated by intricate multimeric machineries.Tim23,the key compone...
关键词：SEQUENCE CONDUCTING structure 
Cryo-EM structure of the human mitochondrial translocase TIM22 complex被引量：1
《Cell Research》2021年第3期369-372,共4页Liangbo Qi Qiang Wang Zeyuan Guan Yan Wu Cuicui Shen Sixing Hong Jianbo Cao Xing Zhang Chuangye Yan Ping Yin 
This work was supported by funds from the Ministry of Science and Technology of China(2018YFA0507700);the National Natural Science Foundation of China(31722017);the Fok Ying-Tong Education Foundation(151021);the Fundamental Research Funds for the Central Universities(2662017PY031);This research was supported by Beijing Advanced Innovation Center for Structural Biology(to Dr.Chuangye Yan).
Dear Editor,Mitochondria are essential organelles in cellular metabolism,homeostasis,and apoptosis.1,2 Most mitochondrial proteins are synthesized as precursors in the cytosol and then imported into mitochondria by sp...
关键词：TRANS INNER COMPLEXES 
Defective arginine metabolism impairs mitochondrial homeostasis in Caenorhabditis elegans被引量：3
《Journal of Genetics and Genomics》2020年第3期145-156,共12页Ruofeng Tang Xin Wang Junxiang Zhou Fengxia Zhang Shan Zhao Qiwen Gan Liyuan Zhao Fengyang Wang Qian Zhang Jie Zhang Guodong Wang Chonglin Yang 
supported by grants from the National Scicnce Foundation of China(91954204 and 31730053);the National Basic Research Program of China(2017YFA0503403)。
Arginine catabolism involves enzyme-dependent reactions in both mitochondria and the cytosol,defects in which may lead to hyperargininemia,a devastating developmental disorder.It is largely unknown if defective argini...
关键词：ARGININE ARGINASE Hyperargininemia Mitochondrial homeostasis C.elegans 
Description of a New Species of Amolops (Anura:Ranidae) from Tibet,China被引量：2
《Asian Herpetological Research》2019年第4期219-229,共11页Shuo QI Zhengyan ZHOU Zhitong LYU Yuyan LU Han WAN Mian HOU Keji GUO Pipeng LI 
supported by Ministry of Science and Technology of China (2014FY210200);The Second National Survey of Terrestrial Wildlife Resources in China;The Second National Survey of Terrestrial Wildlife Resources in Tibet of China
A new species,Amolops pallasitatus sp.nov.is described based on specimens collected from Chentang Town,Dinggyê County,southern Tibet,China.The new species can be distinguished from other known congeners by mitochondr...
关键词：Amolops pallasitatus sp.nov. MITOCHONDRIAL morphology unknown species group torrent frog 
Molecular phylogeny of the genus Clibanarius(Decapoda: Anomura: Diogenidae) based on mitochondrial and nuclear DNA sequences被引量：1
《Journal of Oceanology and Limnology》2019年第5期1686-1697,共12页LI Wenjie CHENG Jiao HUI Min SHA Zhongli 
Supported by the National Key R&D Program of China(No.2018YFD0900804);the Project of the S&T Basic Work from the Ministry of Science and Technology of China(Nos.2014FY110500,2013FY110700);the “Key Research Program of Frontier Sciences” of the Chinese Academy of Sciences(No.QYZDB-SSW-DQC036)
Clibanarius , a genus of hermit crabs, is one of the most diverse genera within Diogenidae. However, studies on the phylogeny within Clibanarius is very limited. We reconstruct the molecular phylogeny of the genus Cli...
关键词：Clibanarius PHYLOGENY molecular evolution 
Novel HMGCS2 pathogenic variants in a Chinese family with mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase deficiency被引量：2
《Pediatric Investigation》2019年第2期86-90,共5页Pengfei Zhang Xuyun Hu Ruolan Guo Jun Guo Wei Li Suyun Qian Chanjuan Hao Jun Liu 
Importance:Mitochondrial 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase deficiency is a rare and underdiagnosed disorder with fewer than 30 patients reported worldwide.The application of whole-exome sequencing in p...
关键词：HMGCS2 mutation Hypoketotic HYPOGLYCEMIA MITOCHONDRIAL HMG-COA SYNTHASE DEFICIENCY Pediatric intensive care unit Whole-exome sequencing 
Polymorphism of mitochondrial tRNA genes associated with the number of pigs born alive
《Journal of Animal Science and Biotechnology》2019年第1期33-42,共10页Dan Wang Chao Ning Hai Xiang Xianrui Zheng Minghua Kong Tao Yin Jianfeng Liu Xingbo Zhao 
supported by the National Key Basic Research Program of China(2014CB138500);the National Natural Science Foundations of China(31672379 and 31661143013)
Background: Mutations in mitochondrial tRNA genes have been widely reported association with human reproductions.It is also important to explore the effect on the number of piglets born alive(NBA).Here,1017 sows were ...
关键词：MITOCHONDRIAL NUMBER BORN ALIVE Pig POLYMORPHISM Transfer RNA 
Aggregation-induced emission luminogen-assisted stimulated emission depletion nanoscopy for super-resolution mitochondrial visualization in live cells被引量：5
《Nano Research》2018年第11期6023-6033,共11页Dongyu Li Xiang Ni Xiaoyan Zhang Liwei Liu Junle Qu Dan Ding Jun Qian 
This work was supported by the Zhejiang Provincial Natural Science Foundation of China （LR17F050001）, the National Natural Science Foundation of China （Nos. 61735016 and 51622305）, and the National Basic Research Program of China （Nos. 2013CB834704 and 2015CB856503）, the PCSIRT （No. IRT13023）, the Science ＆ Technology Project of Tianjin of China （No. 15JCYBJC29800）, the China Postdoctoral Science Foundation （No. 2016M601252）, and the 111 project （B08011）.
A mitochondrial phosphate transporter,McPht gene,confers an acclimation regulation of the transgenic rice to phosphorus deficiency被引量：1
《Journal of Integrative Agriculture》2018年第9期1932-1945,共14页HAN Jiao YU Guo-hong WANG Li LI Wei HE Rui WANG Bing HUANG Sheng-cai CHENG Xian-guo 
supported by the National Key Project for Cultivation of New Varieties of Genetically Modified Organisms,Ministry of Agriculture,China (2016ZX08002005);the National Basic Research Program of China(2015CB150800)
Phosphate transporters play an important role in promoting the uptake and transport of phosphate in plants. In this study, the McPht gene from the Mesembryanthemum crystallinum, a mitochondrial phosphate transporter, ...
关键词：McPht gene phosphorus deficiency phosphate transporter transcriptome sequencing transgenic rice 
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