MITOTIC

作品数:63被引量:108H指数:6
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相关领域:生物学医药卫生更多>>
相关作者:张博周平坤黄琼萍朱学良鄢秀敏更多>>
相关机构:沈阳农业大学军事医学科学院北京大学中国科学院上海生命科学研究院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>
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Synergistic induction of mitotic pyroptosis and tumor remission by inhibiting proteasome and WEE family kinases被引量:1
《Signal Transduction and Targeted Therapy》2024年第8期3467-3482,共16页Zhan-Li Chen Chen Xie Wei Zeng Rui-Qi Huang Jin-E Yang Jin-Yu Liu Ya-Jing Chen Shi-Mei Zhuang 
This study was supported by grants from National Key R&D Program of China(2019YFA0906001 to S.M.Z.);National Natural Science Foundation of China(81930076 to S.M.Z.,32000494 to C.X.);Guangdong Basic and Applied Basic Research Foundation(2023A1515012301 to C.X.);Guangzhou Basic Research Project(2023A04J1753 to C.X.)。
Mitotic catastrophe(MC),which occurs under dysregulated mitosis,represents a fascinating tactic to specifically eradicate tumor cells.Whether pyroptosis can be a death form of MC remains unknown.Proteasome-mediated pr...
关键词:PROTEASOME INHIBITING CATASTROPHE 
Correction: MELK is an oncogenic kinase essential for metastasis, mitotic progression, and programmed death in lung carcinoma
《Signal Transduction and Targeted Therapy》2024年第8期3533-3536,共4页Qin Tang Wan Li Xiangjin Zheng Liwen Ren Jinyi Liu Sha Li Jinhua Wang Guanhua Du 
After online publication of the article[1]the authors noticed inadvertent errors in the panel of 95-D cells(+MELK and-siSlug)invasion in Fig.2J which is partly overlapped with the panel of the 95-D cells(+MELK and+siS...
关键词:MMP7 METASTASIS DEATH 
Safeguarding transcriptional memory: a mitotic bookmarking role for chromatin remodelers
《Signal Transduction and Targeted Therapy》2023年第11期5132-5133,共2页Godwin Sokpor Huu Phuc Nguyen Tran Tuoc 
A recent study published in Nature reveals an interaction between SWI/SNF subunits and mitotic chromatin,which is essential for establishing gene bookmarks and preserving cell identity.1 The findings deepen our unders...
关键词:establishing COMPLEXES PRESERVING 
MELK is an oncogenic kinase essential for metastasis,mitotic progression,and programmed death in lung carcinoma
《Signal Transduction and Targeted Therapy》2021年第1期83-94,共12页Qin Tang Wan Li Xiangjin Zheng Liwen Ren Jinyi Liu Sha Li Jinhua Wang Guanhua Du 
This work was supported by grants from the National Natural Science Foundation of China(81803584 for Qin Tang);China Postdoctoral Science Foundation(2018M640093 for Qin Tang);National Natural Science Foundation of China(81573454 for Jinhua Wang,81703536 for Wan Li);Beijing Natural Science Foundation(7172142);CAMS Innovation Fund for Medical Sciences(2016-I2M-3-007);Technology Major Projects for“Major New Drugs Innovation and Development”(2018ZX09711001-005-025 and 2018ZX09711001-012).
Lung cancer is the fastest growth rate of morbidity and mortality in nearly a decade,and remains difficult to treat.Furthermore,the molecular mechanisms underlying its development are still unclear.In this study,bioin...
关键词:METASTASIS PLK1 LUNG 
MELK is an oncogenic kinase essential for metastasis,mitotic progression,and programmed death in lung carcinoma被引量:10
《Signal Transduction and Targeted Therapy》2020年第1期181-192,共12页Qin Tang Wan Li Xiangjin Zheng Liwen Ren Jinyi Liu Sha Li Jinhua Wang Guanhua Du 
supported by grants from the National Natural Science Foundation of China(81803584 for Qin Tang);China Postdoctoral Science Foundation(2018M640093 for Qin Tang);National Natural Science Foundation of China(81573454 for Jinhua Wang,81703536 for Wan Li);Beijing Natural Science Foundation(7172142);CAMS Innovation Fund for Medical Sciences(2016-I2M-3-007);Technology Major Projects for“Major New Drugs Innovation and Development”(2018ZX09711001-005-025 and 2018ZX09711001-012).
Lung cancer is the fastest growth rate of morbidity and mortality in nearly a decade,and remains difficult to treat.Furthermore,the molecular mechanisms underlying its development are still unclear.In this study,bioin...
关键词:METASTASIS PLK1 LUNG 
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