supported by the National Cancer Institute/the National Institute of Health(1R01CA197976,1R01CA201500);Vincent Memorial Hospital Foundation;the Vincent Center for Reproductive Biology;the Olson Center for Women’s Health;University of Nebraska Medical Center Graduate Studies Fellowship;the Fred&Pamela Buffett Cancer Center(LB595);Colleen’s Dream Foundation;Marsha Rivkin Center for Ovarian Cancer Research(the Barbara Learned Bridge Funding Award);the Co BRE grant from the Nebraska Center for Cellular Signaling/the National Institute of General Medical Science/the National Institute of Health(5P30GM106397)。
Understanding the cell-of-origin of ovarian high grade serous cancer(HGSC)is the prerequisite for efficient prevention and early diagnosis of this most lethal gynecological cancer.Recently,a mesenchymal type of ovaria...