Endophenotypes are heritable quantitative traits that are associated with disease liability, can be measured in both affected and unaffected individuals, and provide much greater power to localize and identify risk ge...
supported in part by grants from the National Institute of Health(HL117652)(to JW);the Academic Health Center(Faculty Research Development Program) of the University of Minnesota (to LL and JW)
Alzheimer's disease (AD) is a prevalent and debilitating neurodegenerative disorder in the elderly. The etiology of AD has not been fully defined and currently there is no cure for this devastating disease. Compell...
funded by grants from the EPSRC(EP/M006204/1);the Michael J Fox Foundation;the Selfridges Group Foundation;the NIHR Oxford Biomedical Research Centre to G.K.T and J.J.D;support from the John Fell Fund(HMD00470).
Extracellular vesicles(EVs)are cell-derived membranous particles that play a crucial role in molecular trafficking,intercellular transport and the egress of unwanted proteins.They have been implicated in many diseases...