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Effect of MTECl on the functional expression of TCRαβ^+3G11^-6C10^-CD4^+CD8^- thymocyte subset
《Chinese Science Bulletin》1999年第17期1571-1576,共6页GE Qing and CHEN WeifengDepartment of Immunology, Beijing Medical University, Beijing 100083, China Corresponding author 
A murine CD4+ thymocyte subset with phenotype of TCRαβ + 3G11- 6C10- CD4 + CD8- CD69 + /- HSAmed/lo contains the cells in relatively functional matured status. The functional property of the cells in this subset is ...
关键词：TCRαβ<sup>+sup>3G11<sup>-sup>6C10<sup>-sup>CD4<sup>+sup> CD8<sup>+sup> CD69<sup>+/-sup> HSA<sup>med/losup> THYMOCYTE SUBSET THYMIC STROMAL cells cytokine 
The Mechanisms of CD8<sup>+</sup> T Cells Exhaustion in the Tumor Microenvironment and Immune Therapy被引量：1
《Journal of Cancer Therapy》2023年第4期161-169,共9页Haiyuan An Shiqi Song Jian Huang 
In the tumor immune microenvironment, CD8<sup>+sup> T cells differentiate towards functional failure. The exhaustion of CD8<sup>+sup> T cells (Tex) showed varying degrees of effect dysfunction, loss of proliferati...
关键词：CD8<sup>+sup> T Cell Exhaustion Exhausted CD8<sup>+sup> T Cells IMMUNOTHERAPY TUMOR 
CXCR5<sup>+</sup> CD8<sup>+</sup> T细胞在儿童传染性单核细胞增多症中的反应特点及临床价值
《临床医学进展》2023年第5期8145-8155,共11页薛健 王建勇 张晓录 谷钰峰 邢海燕 辛毅 王晓莉 李爱敏 
目的:本研究旨在探讨C-X-C趋化因子受体5型(CXCR5) CD8+ T细胞在儿童EBV相关传染性单核细胞增多症(IM)中的反应特点及临床价值。方法:采用流式细胞术及EB病毒(EBV)病原学检查分析入组儿童的外周血,同时收集临床资料进行统计分析。结果:...
关键词：CXCR5<sup>+sup> CD8<sup>+sup> T细胞 EBV相关性IM 流式细胞术 EBV相关性肝损伤 
Specific CD8^+ T cell response immunotherapy for hepatocellular carcinoma and viral hepatitis被引量：15
《World Journal of Gastroenterology》2016年第28期6469-6483,共15页Elia Moreno-Cubero Juan-Ramón Larrubia 
Supported by "Instituto de Salud Carlos Ⅲ",Spain& "European Regional Development Fund(ERDF);a way of making Europe",No.PI12/00130 and No.PI15/00074;and"Gilead Spain&Instituto de Salud Carlos Ⅲ",No.GLD14_00217
Hepatocellular carcinoma (HCC), chronic hepatitis B (CHB) and chronic hepatitis C (CHC) are characterized by exhaustion of the specific CD8<sup>+sup> T cell response. This process involves enhancement of negative co...
关键词：Hepatocellular carcinoma CD8<sup>+sup> T cells Immune checkpoint modulation Chronic viral hepatitis Cytotoxic T-lymphocyte antigen-4 Programmed cell death protein-1 
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