the Key Project of China National Programs for Fundamental Research and Develop-ment (No. 2007CB714306); National Natural Science Foundation of China (No. 20676056)
supported by the National Natural Science Foundation of China(Nos.81430091,81325025,and 81273586);Jiangsu Provincial Promotion Foundation for the Key Lab of Drug Metabolism and Pharmacokinetics(No.BM2012012);the Natural Science Foundation of Jiangsu Province for Outstanding Youth Scholar(No.BK2012026)
Nicotinamide phosphoribosyltransferase(NAMPT) catalyzes the first rate-limiting step in converting nicotinamide to NAD^+, essential for a number of enzymes and regulatory proteins involved in a variety of cellular pro...