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检索条件:"关键词=Na^+/K^+-ATPase "
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Na^+/K^+-ATPase α-subunit in swimming crab Portunus trituberculatus: molecular cloning, characterization, and expression under low salinity stress被引量:5
《Chinese Journal of Oceanology and Limnology》2015年第4期828-837,共10页韩晓琳 刘萍 高保全 王好锋 段亚飞 徐文斐 陈萍 
Supported by the National High Technology Research and Development Program of China(863 Program)(No.2012AA10A409);the National Natural Science Foundation of China(No.41306177);the Special Scientific Research Funds for Central Non-Profit Institutes,Yellow Sea Fisheries Research Institutes(No.20603022013027)
Na^+/K^+-ATPases are membrane-associated enzymes responsible for the active transport of Na^+ and K^+ ions across cell membranes, generating chemical and electrical gradients. These enzymes' α-subunit provides c...
关键词:cloning EXPRESSION Na^+/K^+-ATPase α-subunit Portunus trituberculatus SALINITY 
Changes in growth and osmoregulation during acclimation to saltwater in juvenile Amur sturgeon Acipenser schrenckii被引量:1
《Chinese Journal of Oceanology and Limnology》2010年第3期603-608,共6页赵峰 庄平 章龙珍 侯俊利 
Supported by the National High Technology Research and Development Program of China (863 Program) (Nos. 2004AA603110 and 2008AA10Z227);the National Natural Science Foundation of China (No. 30490234)
We evaluated the ability of juvenile Amur sturgeon (Acipenser schrenckii) to osmoregulate and grow in saltwater. Hatchery-reared juveniles (mean weight 106.8 g, 5-month old) were transferred from freshwater to 10, 20,...
关键词:STURGEON serum osmolality ion concentration Na^+/K^+-ATPase activity chloride cells 
Cationic nanocarriers induce cell necrosis through impairment of Na^+/K^+-ATPase and cause subsequent inflammatory response被引量:24
《Cell Research》2015年第2期237-253,共17页Xiawei Wei Bin Shao Zhiyao He Tinghong Ye Min Luo Yaxiong Sang Xiao Liang Wei Wang Shuntao Luo Shengyong Yang Shuang Zhang Changyang Gong Maling Gou Hongxing Deng Yinglan Zhao Hanshuo Yang Senyi Deng Chengjian Zhao Li Yang Zhiyong Qian Jiong Li Xun Sun Jiahuai Han Chengyu Jiang Min Wu Zhirong Zhang 
Acknowledgments This work was funded by the National Natural Science Foundation of China (81123003) and the National Basic Research Program of China (2010CB529900). We also thank Dr Kang Zhang (University of California, San Diego) for helpful discussions.
Nanocarriers with positive surface charges are known for their toxicity which has limited their clinical appli- cations. The mechanism underlying their toxicity, such as the induction of inflammatory response, remains...
关键词:cationic nanocarriers NECROSIS Na^+/K^+-ATPase inflammation damage-associated molecular patterns 
Steroid-like compounds in Chinese medicines promote blood circulation via inhibition of Na^+/K^+- ATPase被引量:10
《Acta Pharmacologica Sinica》2010年第6期696-702,共7页Ronald JY CHEN Tse-yu CHUNG Feng-yin LI Wei-hung YANG Tzyy-rong JINN Jason TC TZEN 
Aim: To examine if steroid-like compounds found in many Chinese medicinal products conventionally used for the promotion of blood circulation may act as active components via the same molecular mechanism triggered by...
关键词:cardiac glycoside molecular modeling Na^+/K^+-ATPase OUABAIN steroid-like Traditional Chinese Medicine 
Effect of sugar positions in ginsenosides and their inhibitory potency on Na^+/K^+-ATPase activity被引量:11
《Acta Pharmacologica Sinica》2009年第1期61-69,共9页Ronald JY CHEN Tse-yu CHUNG Feng-yin LI Nan-hei LIN Jason TC TZEN 
Aim: To determine whether ginsenosides with various sugar attachments may act as active components responsible for the cardiac therapeutic effects of ginseng and sanqi (the roots of Panax ginseng and Panax notogins...
关键词:cardiac therapeutic effect GINSENOSIDE Na^+/K^+-ATPase molecular modeling steric hindrance 
Insulin induced translocation of Na^+/K^+-ATPase is decreased in the heart of streptozotocin diabetic rats被引量:2
《Acta Pharmacologica Sinica》2009年第12期1616-1624,共9页Klara ROSTA Eszter TULASSAY Anna ENZSOLY Katalin RONAI Ambrus SZANTHO Tamas PANDICS Andrea FEKETE Peter MANDL Agota VER 
To investigate the effect of acute insulin administration on the subcellular localization of Na^+/K^+-ATPase isoforms in cardiac muscle of healthy and streptozotocin-induced diabetic rats. Methods: Membrane fractio...
关键词:rat cardiac muscle streptozotocin-diabetes Na^+/K^+-ATPase isoenzyme REDISTRIBUTION 
Arsenic exposure decreases rhythmic contractions of vascular tone through sodium transporters and K^+ channels
《World Journal of Pharmacology》2014年第2期18-23,共6页Javier Palacios Chukwuemeka R Nwokocha Fredi Cifuentes 
Arsenic-contaminated drinking water is a public health problem in countries such as Taiwan, Bangladesh, United States, Mexico, Argentina, and Chile. The chronic ingestion of arsenic-contaminated drinking water increas...
关键词:Arsenic VASOMOTION Na^+/K^+-ATPase Na^+-K^+-2Cl^- K^ channels Nitric oxide PROSTAGLANDIN Vascular 
Different Na^+/K^+-ATPase signal pathways was involved in the increase of [Ca^2+]i induced by strophanthidin in normal and failing isolated guinea pig ventricular myocytes被引量:2
《Acta Pharmacologica Sinica》2008年第11期1313-1318,共6页Ya-juan QI Su-wen SU Jun-xia LI Ji-he LI Fang GUO Yong-li WANG 
Project supported by the Natural Science Foundation of Hebei Province of China (No 301360).
Aim: To determine whether different Na^+/K^+-ATPase signal transduction pathways have positive inotropic effects on normal ventricular myocytes (NC) and failing ventricular myocytes (FC), and are involved in an...
关键词:chronic heart failure Na^+/K^+-ATPase strophan-thidin CONTRACTILITY calcium transient positiveinotropic effect signal transduction 
Effect of Salinity on the Biosynthesis of Amines in Litopenaeus vannamei and the Expression of Gill Related Ion Transporter Genes被引量:5
《Journal of Ocean University of China2014年第3期453-459,共7页PAN Luqing LIU Hongyu ZHAO Qun 
supported by the National Natural Sciences Foundation of China (31072193);the Scientific Research Foundation for Outstanding Young Scientists of Shandong Province (2006BS07005)
This study examined the effect of salinity on the expression of Na+/K+-ATPase(NKA) α-subunit and vacuolar-type H+-ATPase(V-ATPase) β-subunit gene in the gill of Litopenaeus vannamei. Semi-quantitative reverse transc...
关键词:SALINITY Litopenaeus vannamei biogenic amine Na^+/K^+-ATPase V-ATPASE 
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