益生菌酸性应激的研究进展  

Research progress of acid tolerance response of probiotics

作　　者：刘怀龙[1] 孟祥晨[1] 庄翘楚[1] 

机构地区：[1]东北农业大学乳品科学教育部重点实验室/食品学院,黑龙江哈尔滨150030

出　　处：《食品工业科技》2008年第6期300-303,共4页Science and Technology of Food Industry

基　　金：国家"863"高科技研究发展计划项目

摘　　要：乳杆菌和双歧杆菌是两种应用较多的益生菌,益生菌多以发酵乳制品作为载体,而发酵乳制品本身属于低酸性食品;另外,益生菌制剂在被食用时,又要经过人体消化道的低酸性环境。以上这些酸胁迫作用都会使益生菌的活性下降,而亚致死酸性应激可以提高益生菌对酸的耐受力,有助于益生菌在消化道逆环境中的存活。因此,提高益生菌的酸性应激具有非常重要的意义,本文主要综述了益生菌酸性应激可能的机制以及提高益生菌酸耐受力的方法。Lactobacillus and Bifidobacterium are two kinds of probiotics which are utilized in many areas including medicine,food industry and feed industry. The preferred delivery vehicles for probiotics are fermented milks which present an acid challenge. Probiotics for human consumption can also encounter the acidic environment of gastric juice when they transit the gastrointestinal tract. The acid stress will decrease the viability of probiotics. Because the acid tolerance response can improve the acid tolerance and the survival of probiotics, it is necessary to enhance the acid tolerance response. The potential mechanism of acid stress in probiotics and the methods for improving the acid tolerance of probiotics were reviewed in this paper.

关 键 词：益生菌 酸性应激 应激蛋白 细胞膜 

分 类 号：TS201.3[轻工技术与工程—食品科学]