双歧杆菌的耐氧机制  

The oxygen tolerance mechanism of bifidobacteria

作　　者：桂仕林[1] 孟祥晨[1] 张久龙[1] 

机构地区：[1]东北农业大学乳品科学教育部重点实验室,食品学院,黑龙江哈尔滨150030

出　　处：《食品工业科技》2008年第7期280-283,共4页Science and Technology of Food Industry

摘　　要：双歧杆菌对氧气敏感,这主要是由于双歧杆菌缺少有效的活性氧清除机制,导致活性氧在细胞内积累,对细胞形成毒害作用。但是最近研究发现,不同双歧杆菌对氧存在敏感性差异,甚至发现了一些耐氧性极高的双歧杆菌。通过对不同耐氧性的双歧杆菌进行比较研究发现:NADH氧化酶和/或NADH过氧化物酶活力是导致双歧杆菌耐氧性差异的主导因素,NADH氧化酶的类型也影响着双歧杆菌的耐氧性;另外环丙烷脂肪酸的含量也与双歧杆菌耐氧性差异有关。目前对双歧杆菌耐氧机制的研究仍主要集中在细胞水平上,在分子水平上的研究还有待进一步开展。Bifidobacteria are oxygen-sensitive bacteria. In the presence of oxygen, bifidobacteria can＇t convert reactive oxygen into nontoxic molecules, these compounds will accumulate in the cell and cause cell death from oxidative damage. However, bifidobacteria recently were found to be different in the sensitivity to oxygen and even some highly oxygen-tolerant bifodobacteria were found. Through the research into the difference of the oxygen-tolerant and oxygen-sensitive bifidobacteria strains, they found that the content of NADH oxidase and/or NADH peroxidase significantly influence the oxygen tolerance of bifidobacteria and the type of NADH oxidase also influences the oxygen tolerance of bifidobacteria. In addition, the content of cyclopropane fatty acid also influences the oxygen tolerance of bifidobacteria. At present, the researches into oxygen tolerance mechanism of bifidobacteria were mainly done at a cellular level, and the more researches should be done at a molecular level in the future.

关 键 词：双歧杆菌 NADH氧化酶 NADH过氧化物酶 环丙烷脂肪酸 

分 类 号：TS201.3[轻工技术与工程—食品科学]