生物活性肽研究进展  

Researching advancement of bioactive peptides

作　　者：刘海军[1] 乐超银[1] 邵伟[2] 叶晶龙[1] 潘虹[1] 李金鞠[1] 

机构地区：[1]三峡大学生物技术中心,湖北宜昌443002 [2]三峡大学化学与生命科学学院,湖北宜昌443002

出　　处：《中国酿造》2010年第5期5-8,共4页China Brewing

基　　金：中国博士后基金项目(20060390775);三峡大学研究生科研创新基金资助项目(61)

摘　　要：氨基酸彼此以酰胺键相连而形成的化合物称作肽,并有寡肽和多肽之分,前者一般含10个以下的氨基酸残基,后者含10-50个氨基酸残基。由于肽的相对分子量对于蛋白质小而且表现为一定的生物活性如降血压、提高免疫、抗癌等,故而称为生物活性肽。伴随分子生物学、生物化学技术的飞速发展,人们对生物活性肽的认识和利用水平得到不断的提高。文中从生物活性肽的来源、制备、功能及应用等方面,对生物活性肽的研究作了一个比较全面的综述。Peptides are composed of amino acids linked by amide bond, which is divided into two groups as oligopcptides and polypeptides, and the former generally have less than 10 amino acids residues, the later have 10-50 amino acids residues. Peptides, with relative smaller molecular weights than proteins, were usually called bioactive peptides because of definite biological activities, such as lowering blood pressure, improving immunity, resisting cancer, etc. With the rapid development of molecular biology and biochemical technology, understanding and utilization of peptides also had been continuously improved. A comprehensive overview about the source, preparation, functions and utilizations ofpeptides was given in this paper.

关 键 词：生物活性肽 化学合成 酶法 发酵法 

分 类 号：TS202.3[轻工技术与工程—食品科学]