乳酸菌胞外多糖的生物合成及其遗传调控  

Biosynthesis and Genetic Regulation of Exopolysaccharides from Lactic Acid Bacteria

作　　者：姚晶[1] 任婧[2] 吴正钧[2] 王荫榆[2] 郭本恒[1,2] 

机构地区：[1]上海海洋大学食品学院 [2]乳业生物技术国家重点实验室光明乳业股份有限公司技术中心,上海200436

出　　处：《食品与发酵工业》2011年第2期11-16,共6页Food and Fermentation Industries

基　　金："十一五"国家科技支撑计划(2006BAD04A14;2006BAD04A06)

摘　　要：作为食品级的乳酸菌分泌的胞外多糖,由于其具有很多优良的功能特性,成为了近年来的研究热点。胞外多糖产量偏低限制了其工业化应用,因此从基因水平上探索增加乳酸菌胞外多糖产量的途径是大有裨益的。文中详细阐述了胞外多糖的分类、结构,同型多糖和异性多糖生物合成过程及其差异,以及在合成过程中的遗传调控,并介绍了一些增加产量的有效调控手段,为深入的研究提供理论参考。Exopolysaccharides is produced by Lactic acid bacteria which is General Recognized As Safe status （GRAS）. As its excellent functions, it is becoming a research hotspot recently. However, its industrial application is limited by the low production level. Therefore, it is significant for studying the genetics to improve the production. This paper mainly concerns about the classification and structure of exopolysaceharides, biosynthesis of homopolysaccharides and heteropolysaccharides, besides the discrepancies between these two exopolysaccharides. Genetic regulation and some effective regulation measures are closely discussed as well. This paper should provide a theoretical reference for further research.

关 键 词：乳酸菌 胞外多糖 生物合成 遗传调控 

分 类 号：Q53[生物学—生物化学]