蓝莓提取物对金黄色葡萄球菌的抑制作用研究  

The Extracts of Blueberries against Growth of Staphyloccocus aureus

作　　者：沈潇[1] 孙晓红[1] 赵勇[1] 谢庆超[1] 吴启华 潘迎捷[1] 

机构地区：[1]上海海洋大学食品学院,上海水产品加工及贮藏工程技术研究中心,上海201306 [2]美国缅因大学食品科学与人类营养系,缅因04469

出　　处：《天然产物研究与开发》2012年第11期1622-1625,1599,共5页Natural Product Research and Development

基　　金：上海市教育委员会科研创新项目资助(11YZ159);上海市科学技术委员会部分地方院校能力建设项目(11310501100);上海市教育委员会重点学科建设项目资助(J50704)

摘　　要：本文以四种栽培蓝莓为主要研究对象,通过与山梨酸钾抑菌效果的比较,研究了蓝莓提取物对金黄色葡萄球菌(AB91093)的抑制作用,并测定了蓝莓中总酚酸和还原糖的含量。结果表明,蓝莓对金黄色葡萄球菌具有显著的抑菌效果。四种蓝莓提取物中,Elliott和Darrow提取物对金黄色葡萄球菌的抑制效果显著,分别在300 mg/mL和350 mg/mL时可明显抑制金黄色葡萄球菌的生长,450 mg/mL时能完全杀死金黄色葡萄球菌。蓝莓的抑菌能力与其酚酸含量正相关,与还原糖含量负相关。而山梨酸钾对金黄色葡萄球菌的MIC和MBC分别为100 mg/mL和200 mg/mL。Blueberry fruits from four commercial cultivars grown under same conditions at the same location and possition were analyzed for antimicrobial activity against Staphyloccocus aureus. We also investigated the content of total phenolic compounds and reducing surge of four blueberries. The results demonstrated that four blueberries could inhibit the growth of S. aureus. Elliott and Darrow were the best inhibitor to S. aureus, and Elliott and Darrow can inhibit S. aureus at 300 mg/mL and 350 mg/mL, respectively. They can kill S. aureus at 450 mg/mL. All tested blueberries extracts showed very good antimicrobial activity with dose-effect dependent, and antimicrobial activity were positive correlation among the content of total phenolics. The negative correlation among the content of reducing sugar and antimicrebial activity was also observed. However,the MIC and MBC of potassium sorbate against S. aureus was 100 mg/mL and 200 mg/mL,respectively.

关 键 词：蓝莓 山梨酸钾 抑菌能力 多酚 还原糖 

分 类 号：TS207.4[轻工技术与工程—食品科学]