香蕉粉毒理学安全评价及减肥功效研究  

Study on safety toxicology evaluation of banana powder and function in reducing weight

作　　者：白永亮[1] 徐勇[1,2] 黄志强[1] 陈庆发[1] 杨永国 杨公明[1] 

机构地区：[1]华南农业大学食品学院,广东广州510642 [2]广东省食品工业研究所公共实验室,广东广州510308 [3]佛山蕉业生物科技有限公司,广东佛山528231

出　　处：《食品工业科技》2012年第24期406-409,共4页Science and Technology of Food Industry

基　　金：国家星火计划项目(2005EA780014);东莞市科技计划资助项目(200910810100600);广州市科技计划项目(12C12101661)

摘　　要：通过急性经口毒性实验研究了小鼠灌胃香蕉粉后所产生的毒性反应和死亡情况,并以卫生部保健食品减肥功能学评价程序与检验方法为依据,以SPF级雄性SD大鼠为研究对象,采用大鼠肥胖模型法,研究了香蕉粉的减肥功效。结果表明:给药后连续观察14d,小鼠活动正常、皮毛光亮,无异常分泌物,体重正常增长,无一小鼠死亡。全部存活小鼠大体解剖,肉眼观察未发现组织脏器体积、颜色、质地等出现改变;香蕉粉可使高脂饲料引起的营养性肥胖模型大鼠的体重明显减轻,并能显著降低大鼠Lee’s指数和脂肪指数,降低血清总胆固醇(TC)、血清甘油三酯(TG)以及低密度脂蛋白胆固醇(LDL-C)含量(p<0.05),而高密度脂蛋白胆固醇(HDL-C)明显升高。因此,香蕉粉对营养型肥胖大鼠有显著的减肥作用。Acute oral toxicity test of banana powder was studied. And according to the testing assessment of weight-losing function of health food published by Ministry of Health,the effect of banana powder on weight losing of SPF grade SD male rats with nutritional obesity was studied. Through continuous observation for 14d after the administration of banana powder,the activity of mice was normal with bright fur,no abnormal secretions,normal weight gain and no mouse dead. Visual inspection after gross anatomy of all surviving mice revealed no changes in organ volume,color and texture. The treatment of banana powder could significantly decrease body weight,fat tissue weight around the testicle and kidney, body fat percentage and Lee＇s index of the rats （p〈0.05）. Moreover,the serum levels of total cholesterol （TC）,total triglyceride （TG） and low density lipoprotein cholesterol（LDL-C） were markedly decreased by banana powder while high density lipoprotein cholesterol（HDL-C） was significantly increased（p〈0.05）. Altogether,the result indicated that banana powder had an effective function of weight losing.

关 键 词：香蕉粉 抗性淀粉 大鼠 减肥 

分 类 号：TS201.4[轻工技术与工程—食品科学]