三孢布拉霉发酵生产类胡萝卜素的产业化关键点探讨  

Critical control points of industrial carotenoid production by Blakeslea trispora

作　　者：范超 洪皓 李妍 吴文忠 FAN Chao;HONG Hao;LI Yan;WU Wen-zhong(INNOBIO Corporation Limited,Dalian 116600,China)

机构地区：[1]大连医诺生物股份有限公司,辽宁大连116600

出　　处：《食品与发酵工业》2018年第5期284-290,共7页Food and Fermentation Industries

摘　　要：三孢布拉氏霉菌代谢可产生天然的β-胡萝卜素和番茄红素,该菌株的性能已被广泛认可,并已实现工业化生产。文中对三孢布拉氏霉菌的代谢途径、相关基因、发酵调控和菌株诱变改良等产业化过程中的关键点进行了综述。Natural β-carotene and lycopene can be produced by Blakeslea trispora. The property of the strain has been recognized and industrialized. This review summarizes the critical control points and the solutions during industrialization,such as metabolic pathways,relevant genes,modulation of fermentation,and mutation of the strain.

关 键 词：三孢布拉氏霉菌 产业化 番茄红素 Β-胡萝卜素 发酵 

分 类 号：TQ929[轻工技术与工程—发酵工程]