蛋源性活性组分对炎症性肠病的缓解作用研究进展  

A Review of Relieving Effects of Bioactive Egg Components on Inflammatory Bowel Disease

作　　者：张梦雅[1] 赵燕[2] 徐明生[1] 姚瑶[1] 汪雄[1] 涂勇刚[1] ZHANG Mengya;ZHAO Yan;XU Mingsheng;YAO Yao;WANG Xiong;TU Yonggang(Jiangxi Key Laboratory of Natural Products and Functional Food, Jiangxi Agricultural University, Nanchang 330045, China;Engineering Research Centre of Biomass Conversion, Ministry of Education, Nanchang University, Nanchang 330047, China)

机构地区：[1]江西农业大学江西省天然产物与功能食品重点实验室,江西南昌330045 [2]南昌大学生物质转化教育部工程研究中心,江西南昌330047

出　　处：《食品科学》2018年第5期321-328,共8页Food Science

基　　金：江西省自然科学基金项目(20171BAB204027);江西省杰出青年人才资助计划项目(20162BCB23031);江西省青年科学家培养对象计划项目(20153BCB23028)

摘　　要：炎症性肠病是发生在肠道的慢性且反复发作的炎性疾病。传统的药物治疗虽能缓解临床症状但却存在一定的副作用。蛋源性活性组分是近期食品科学领域研究的热点之一,禽蛋组分的抗菌、抗病毒、降血压、抗氧化、抗炎以及免疫调节等功能活性已被相继证实。蛋源性活性组分的开发应用有望为炎症性肠病提供新的治疗策略。本文综述了氨基酸、多肽、蛋白质和脂质这些蛋源性活性组分的抗炎活性以及其对炎症性肠病缓解作用的分子作用机制的研究进展,并对其研究进行了展望,以期为蛋源性抗肠炎活性组分的进一步深入研究和应用开发提供参考。Inflammatory bowel diseases is a group of chronic and recurrent inflammatory disorders that occur in the intestine.Traditional drug therapy can relieve clinical symptoms,but may cause some side effects.Bioactive egg components are one of the hot research topics in the field of food science nowadays.Anti-bacterial,anti-viral,anti-hypertensive,anti-oxidative,anti-inflammatory and immunoregulatory activities of bioactive egg components have been confirmed.The development and application of biological egg components is expected to open new therapeutic strategies for inflammatory bowel disease.In this paper,we review recent advances in understanding the anti-inflammatory activity of egg derived amino acids,peptides,proteins and lipids,as well as the molecular mechanisms for the alleviation of inflammatory bowel disease by these bioactive components.Furthermore,potential directions for future research are discussed.The aim of this review is to provide a basis for further study and application of biological egg components.

关 键 词：蛋源性生物活性组分 炎症性肠病 抗炎机制 

分 类 号：TS253.1[轻工技术与工程—农产品加工及贮藏工程]