基质辅助激光解吸电离质谱成像技术及其在食品分析中的应用  

A Review of the Application of Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging in Food Analysis

作　　者：殷小钰 陈倩[1] 韩齐[1] 孔保华[1] YIN Xiaoyu;CHEN Qian;HAN Qi;KONG Baohua(College of Food Science,Northeast Agricultural University,Harbin 150030,China)

机构地区：[1]东北农业大学食品学院,黑龙江哈尔滨150030

出　　处：《食品科学》2018年第7期298-304,共7页Food Science

基　　金：国家重点基础研究发展计划(973计划)项目(2016YFD0401504);黑龙江省应用技术研究与开发计划项目(GA15B302)

摘　　要：基质辅助激光解吸电离质谱成像(matrix-assisted laser desorption ionization mass spectrometry imaging,MALDI-MSI)技术是一种新型的分析技术,具有无需提取、分离、纯化待测样品,操作简便、灵敏度高等优点,广泛应用于生物、医学等领域。虽然其在食品领域还未建立完善的测定方法,但由于该技术可对食品中的化合物进行空间成像分析,故其在食品领域中也将具有广阔的应用前景。本文在介绍MALDI-MSI技术成像原理的基础上,综述了该技术的样品制备和在食品成分分析中的应用,并对其应用前景进行了展望,以期为MALDI-MSI技术在食品研究中的应用和推广提供借鉴。Matrix-assisted laser desorption ionization mass spectrometry imaging(MALDI-MSI),a new analytical technique,is widely used in biological,medical and other fields due to its usefulness for the detection of compounds without extraction,purification,separation,or labeling.Although the methodology of MALDI-MSI in food science is not yet fully established,its application is expected to open up a new insight in food science.In this paper,the principle of MALDI-MSI imaging is described and its application in sample preparation and food analysis is reviewed.Future prospects for MALDI-MSI application are also discussed.We expect that this review which will provide a basis for the application and popularization of MALDI-MSI in food analysis.

关 键 词：基质辅助激光解吸电离质谱成像 食品分析 成像原理 样品制备 应用 

分 类 号：TS207.3[轻工技术与工程—食品科学]