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作 者:Steffen Norgaard Roger Pocock
机构地区:[1]Development and Stem Cells Program, Monash Biomedicine Discovery Institute and Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria, Australia [2]Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark
出 处:《Neural Regeneration Research》2019年第8期1367-1368,共2页中国神经再生研究(英文版)
基 金:supported by a grant from an NHMRC Project Grant(GNT1105374);NHMRC Senior Research Fellowship(GNT1137645);a Victorian Endowment for Science,Knowledge and Innovation Fellowship(VIF23)(to RP)
摘 要:Understanding fundamental mechanisms governing axon outgrowth and guidance can inform the development of therapeutic strategies to restore neuronal function damaged though injury or disease. Axons navigate the extracellular environment by responding to guidance cues that bind to cell surface receptors to relay information intracellularly via Rho GTPase family members, including the Rac GTPases.
关 键 词:RAC GTPASES domain-specific FUNCTIONS NEURONAL DEVELOPMENT
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