海洋食品中海洋多糖、生物活性肽与皂苷类化合物改善代谢综合征的机制  

The Mechanism of Improving Metabolic Syndrome by Marine Polysaccharides,Bioactive Peptides and Saponins in Marine Food

作　　者：陆佳俊 刘春娥[2] 黄昆仑[1] 贺晓云[1] Lu Jiajun;Liu Chune;Huang Kunlun;He Xiaoyun(College of Food Science and Nutritional Engineering,China Agricultural University,Beijing 100083;Yantai Institute of China Agricultural University,Yantai 264670,Shandong)

机构地区：[1]中国农业大学食品科学与营养工程学院,北京100083 [2]中国农业大学烟台研究院,山东烟台264670

出　　处：《中国食品学报》2021年第9期346-351,共6页Journal of Chinese Institute Of Food Science and Technology

摘　　要：代谢综合征是一种包含多组分的代谢异常疾病,发病率逐渐升高。海洋食品中的生物活性物质,如海洋多糖、生物活性肽和皂苷类化合物因独特的结构和降血糖、降血脂、抗高血压、免疫调节等多种生理功能而越来越受到人们的关注。本文综述近年来海洋食品中海洋多糖、生物活性肽以及皂苷类化合物改善代谢综合征的机制,例如海洋多糖通过调节肠道菌群组成与降解成短链脂肪酸而改善糖脂代谢,其具体机制是乳酸杆菌、双歧杆菌等有益菌改善肠道和免疫系统的相关功能;短链脂肪酸与G蛋白偶联受体40家族结合,通过调节饱腹激素的分泌,降低食欲的同时增加能量消耗,从而实现能量代谢平衡,改善代谢综合征。Metabolic syndrome is a metabolic abnormal disease containing multiple components,and its incidence rate is gradually increasing.Bioactive substances in marine food,such as marine polysaccharides,bioactive peptides and saponins,have been paid more and more attention because of its unique structure and hypoglycemic,hypolipidemic,anti-hypertensive and immune regulation.The mechanism of improving metabolic syndrome by marine polysaccharides,bioactive peptides and saponins in marine food are summarized to provide reference to the applications of these bioactive substances.For example,marine polysaccharides improve glycolipid metabolism by regulating the composition of intestinal flora and degradation into short chain fatty acids.The mechanism is that Lactobacillus,Bifidobacterium and other beneficial bacteria improve the related functions of intestinal tract and immune system,as well as the combination of short chain fatty acids and G-protein-coupled receptor 40 family.By regulating the secretion of satiety hormone,it can reduce appetite and increase energy consumption,so as to improve metabolic syndrome and achieve balance between quantity and metabolism.

关 键 词：海洋多糖 生物活性肽 皂苷类化合物 代谢综合征 糖脂代谢 

分 类 号：TS254.1[轻工技术与工程—水产品加工及贮藏工程]