便携式生物传感器在真菌毒素检测中的应用研究进展  

A Review of Portable Biosensors for the Field Detection of Mycotoxins

作　　者：王沂雯 刘晏霖 付瑞杰 刘浩然 周静 赵其阳[1,2] 王成秋 焦必宁[1,2] 何悦 WANG Yiwen;LIU Yanlin;FU Ruijie;LIU Haoran;ZHOU Jing;ZHAO Qiyang;WANG Chengqiu;JIAO Bining;HE Yue(Citrus Research Institute,Southwest University,Chongqing 400712,China;Quality Supervision and Testing Centre for Citrus and Seedling,Ministry of Agriculture and Rural Affairs,Chongqing 400712,China)

机构地区：[1]西南大学柑桔研究所,重庆400712 [2]农业农村部柑桔及苗木质量监督检验测试中心,重庆400712

出　　处：《食品科学》2022年第11期234-245,共12页Food Science

基　　金：“十三五”国家重点研发计划重点专项(2019YFC1605604);国家农产品质量安全风险评估重大专项(GJFP2019012);现代农业产业技术体系建设专项(CARS-26)。

摘　　要：食品在贮藏、运输和加工过程中易受真菌侵染。由真菌代谢所产生的真菌毒素对食品造成了严重的污染,并引发了严峻的食品安全问题。传统的检测方法大多需要大型精密仪器设备、繁琐的操作步骤以及专业技术人员,这在很大程度上限制了这些方法在现场即时检测中的应用。便携式传感器允许用户利用小型化设备实时监测真菌毒素的污染情况,具有操作简便、用户友好、检测速度快、灵敏度高等优点,受到越来越多的科研工作者及社会各界人士的青睐。本文重点对试纸条、个人血糖仪、手持式pH计、气压计、智能手机、微流控芯片以及基于可视化、电化学、等离子体等输出信号的便携式生物传感器在真菌毒素检测中的应用和发展前景进行综述,以期为真菌毒素新型便携式生物传感器的研发提供参考。Foods are susceptible to fungal infection in the process of storage,transportation,and processing.Mycotoxins,produced by fungal metabolism,are serious food pollutants and can cause serious food safety problems.Most of the traditional analytical methods for the detection of mycotoxins need large-scale precision instruments or equipment,cumbersome operation steps,and professional workers,which limits the application of these methods in on-site detection to a large extent.Portable sensors which allow users to monitor mycotoxin contamination in real time with miniaturized equipment have been developed.They have the advantages of simple operation,user friendliness,rapidity and high sensitivity,making them popular among researchers.This paper reviews the application and prospects of test strips,personal glucose meters,handheld pH meters,pressure meters,smartphones,microfluidic chips and portable biosensors based on visualization,electrochemistry,plasma and other signal output in the detection of mycotoxins.We anticipate that this review will cause more researchers to devote themselves to the development of new portable biosensors for the detection of mycotoxins to ensure food safety and human health.

关 键 词：便携式 生物传感器 真菌毒素 现场检测 

分 类 号：TS207.3[轻工技术与工程—食品科学]