纸上微型实验室在食品检测领域的研究进展  

Progress in Lab on Paper in the Field of Food Safety Detection

作　　者：陈洋[1] 杨湛森 王鑫[1] 宋光春 黄荟娴 徐瑗聪 罗云波[1] 黄昆仑[1] 程楠[1] CHEN Yang;YANG Zhansen;WANG Xin;SONG Guangchun;HUANG Huixian;XU Yuancong;LUO Yunbo;HUANG Kunlun;CHENG Nan(College of Food Science and Nutritional Engineering,China Agricultural University,Beijing 100083,China;Faculty of Environment and Life,Beijing University of Technology,Beijing 100024,China)

机构地区：[1]中国农业大学食品科学与营养工程学院,北京100083 [2]北京工业大学环境与生命学部,北京100024

出　　处：《食品科学》2023年第3期246-257,共12页Food Science

基　　金：国家自然科学基金青年科学基金项目(32001787);中国农业大学2115人才工程项目。

摘　　要：“纸上微型实验室”是以纸为基底的微型分析系统,其因高灵敏、低成本、便携化、可批量生产等独特优势突破了传统检测技术的局限,在食品现场快速检测领域展现出巨大应用潜力。本文梳理了典型的“纸上微型实验室”,分别对纸层析法、化学试纸、侧流层析试纸条、纸基微流控分析装置和合成生物学纸进行全面综述,并重点介绍了“纸上微型实验室”在食品检测领域中的应用,最后讨论了纸基分析方法的优势、挑战和发展趋势,以期为“纸上微型实验室”更全面地应用于食品检测领域提供理论支撑。“Lab on paper”is a paper-based microanalytical system with unique advantages such as high sensitivity,low cost,portability,and mass production,which breaks through the limitations of traditional detection technologies and shows great potential in the field of rapid on-site food detection.In this paper,the typical“labs on paper”,including chromatographic paper,chemical test chip,lateral flow assay(LFA),microfluidic paper-based analytical devices(μPADs),and synthetic biological paper,are systematically reviewed.Special emphasis is put on the application of“lab on paper”in the field of food detection.Finally,the advantages,challenges,and future prospects of paper-based analytic methods are discussed,which may provide theoretical support for better application of“lab on paper”in the field of food detection.

关 键 词：纸上微型实验室 纸基分析装置 食品检测 

分 类 号：TS207.3[轻工技术与工程—食品科学] O657[轻工技术与工程—食品科学与工程]