基于色盲遗传学教学素材的挖掘及其在教学中应用  

The construction of genetics teaching resources related to colour blindness and their application in genetics teaching

作　　者：毛春晓 Chunxiao Mao(School of Life Sciences,East China Normal University,Shanghai 200241,China)

机构地区：[1]华东师范大学生命科学学院,上海200241

出　　处：《遗传》2024年第4期346-354,共9页Hereditas（Beijing)

基　　金：华东师范大学课程建设项目(编号:40400-22301-512200/001/223)资助。

摘　　要：在遗传学课程教学中,红绿色盲是X连锁隐性遗传的典型案例。然而红绿色盲只是比较常见的色觉障碍,还有其他临床分型。不同的色盲遗传方式可能不同,致病基因也不同。近年来,关于色盲的致病基因、分子机制、基因治疗等方面取得了很大进展,相关研究成果可以作为很好的素材在遗传学教学中进行使用。本文阐述了基于色盲的遗传学教学素材的挖掘及其在本校遗传学课程中“绪论”“遗传的细胞和分子基础”“伴性遗传”“染色体畸变”“基因突变”“遗传学进展”等章节教学中的应用。通过课堂教授与问答,辅以课后文献检索与阅读,使学生在更好掌握遗传学基本内容的基础上,能拓宽遗传学学术视野,激发学习兴趣。Red-green colour blindness is a classic example for the teaching of X-linked recessive inheritance in genetics course.However,there are lots of types of color vision deficiencies besides red-green colour blindness.Different color vision deficiencies caused by different genes may have different modes of inheritance.In recent years,many research achievements on colour blindness have been made.These achievements could be used as teaching resources in genetics course.Here,we summarize the construction of genetics teaching resources related to colour blindness and their application in genetics teaching in several chapters such as introduction,cellular and molecular basis of genetics,sex-linked inheritance,chromosomal aberration,gene mutation and advances in genetics.Teacher could use the resources in class or after class with different teaching methods such as questioning teaching method and task method.It may expand students’academic horizons and inspire students'interest in genetics besides grasping basic genetic knowledge.

关 键 词：色盲 遗传学 色觉 伴性遗传 全色盲 

分 类 号：G642[文化科学—高等教育学] R-4[文化科学—教育学]