Acknowledgments We thank Xueliang Zhu for discussion, Shiyi Guo, Di An, Ruining Liu, Long Miao, and Chuanmao Zhang for technical assistance, and Tso-Pang Yao and Steven Y Cheng for reagents. This work was supported by grants from the National Basic Research Program of China (2012CB945002) and the National Natural Science Foundation of China (31130015, 31271437, and 31371382).
Cilia are hair-like organelles extending from the cell surface with important sensory and motility functions. Ciliary defects can result in a wide range of human diseases known as ciliopathies. However, the molecular ...