CILIOGENESIS

作品数：15被引量：36H指数：5
导出分析报告
相关领域：生物学更多>>
相关期刊：《Medicinal Plant》《Science China(Life Sciences)》《Genes & Diseases》《Bone Research》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划高等学校学科创新引智计划更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Cerebral furin deficiency causes hydrocephalus in mice
《Genes & Diseases》2024年第3期438-451,共14页Shiqi Xie Xiaoyong Xie Jing Tang Biao Luo Jian Chen Qixin Wen Jianrong Zhou Guojun Chen 
supported by grants from the National Natural Science Foundation of China(No.81971030,82271461 to GJ Chen).
Furin is a pro-protein convertase that moves between the trans-Golgi network and cell surface in the secretory pathway.We have previously reported that cerebral overexpres-sion of furin promotes cognitive functions in...
关键词：ASTROCYTE CILIOGENESIS Conditionalknockout Ependymal FURIN HYDROCEPHALUS PROTEOMICS 
Cilia regeneration requires an RNA splicing factor from the ciliary base被引量：1
《Cell Regeneration》2022年第1期303-314,共12页Kaiming Xu Guangshuo Ou 
This work was supported by the National Natural Science Foundation of China(grants 31991190,31730052,31525015,31861143042,31561130153,31671444,31871352);the National Key R&D Program of China(2017YFA0503501,2019YFA0508401,and 2017YFA0102900)。
Cilia are microtubule-based organelles projected from most eukaryotic cell surfaces performing cell motility and signaling.Several previously recognized non-ciliary proteins play crucial roles in cilium formation and ...
关键词：PRP-8/PRPF8 RNA splicing factor CILIOGENESIS Cilium regeneration 
Inhibition of Ciliogenesis Enhances the Cellular Sensitivity to Temozolomide and Ionizing Radiation in Human Glioblastoma Cells被引量：1
《Biomedical and Environmental Sciences》2022年第5期419-436,共18页WEI Li MA Wei CAI Hui PENG Shao Peng TIAN Huan Bing WANG Ju Fang GAO Lan HE Jin Peng 
supported by the National Natural Sciences Foundation of China[31870851 and 31471953];the Nonprofit Central Research Institute Fund of Chinese Academy of Medical Sciences[2019PT320005];the Science and Technology Research Project of Gansu Province[145RTSA012 and 20JR5RA555];the Youth Innovation Promotion Association CAS[2021415]
Objective To investigate the function of primary cilia in regulating the cellular response to temozolomide(TMZ)and ionizing radiation(IR)in glioblastoma(GBM).Methods GBM cells were treated with TMZ or X-ray/carbon ion...
关键词：Primary cilia GLIOBLASTOMA Cellular sensitivity TEMOZOLOMIDE Ionizing radiation Autophagy DNA damage response DNA-PK 
Theobroma cacao improves bone growth by modulating defective ciliogenesis in a mouse model of achondroplasia被引量：1
《Bone Research》2022年第1期137-149,共13页Ludovic Martin Nabil Kaci Catherine Benoist-Lasselin Marine Mondoloni Suzanne Decaudaveine Valentin Estibals Maxence Cornille Léa Loisay Justine Flipo Benoît Demuynck Maria de la Luz Cádiz-Gurrea Florent Barbault Salvador Fernández-Arroyo Laurent Schibler Antonio Segura-Carretero Emilie Dambroise Laurence Legeai-Mallet 
This program received a state subsidy managed by the National Research Agency under the “Investments for the Future” Program bearing the reference ANR-10-IAHU-01;Some of the work presented here was funded by the European Community’s Seventh Framework Program under grant agreement 602300 (the SYBIL program (https://www.sybil-fp7.eu/) is funded by the MRC (MC_UU_000007/9))
A gain-of-function mutation in the fibroblast growth factor receptor 3 gene(FGFR3)results in achondroplasia(ACH),the most frequent form of dwarfism.Constitutive activation of FGFR3 impairs bone formation and elongatio...
关键词：inhibited arrangement eliminated 
NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis被引量：5
《Cell Research》2021年第11期1199-1211,共13页Min Liu Wen Zhang Min Li Jiaxing Feng Wenjun Kuang Xiying Chen Feng Yang Qiang Sun Zhangqi Xu Jianfeng Hua Chunxia Yang Wei Liu Qiang Shu Yuehong Yang Tianhua Zhou Shanshan Xie 
This work was supported by the National Natural Science Foundation of China(31671394,31701214,91740205,and 31620103911);the National Key R&D Program of China(2019YFA0802202);the 111 Project(B13026).
Primary cilia extending from mother centrioles are essential for vertebrate development and homeostasis maintenance.Centriolar coiled-coil protein 110(CP110)has been reported to suppress ciliogenesis Initiation by cap...
关键词：MOTHER media SELECTIVE 
O-GIcNAc transferase regulates centriole behavior and intraflagellar transport to promote ciliogenesis被引量：3
《Protein & Cell》2020年第11期852-857,共6页Fan Yu Te Li Yanchao Sui Qingxia Chen Song Yang Jia Yang Renjie Hong Dengwen Li Xiumin Yan Wei Zhao Xueliang Zhu Jun Zhou 
We thank Dr.Wen Ning for providing the Ube-Cre-ERT2 mice.This work was supported by grants from the National Key R&D Program of China(2017YFA0503502);the National Natural Science Foundation of China(31991193).Fan Yu,Te Li。Yanchao Sui,Qingxia Chen,Song Yang,Jia Yang,Renjie Hong,Dengwen they have no conflict of interest.All institutional and national guidelines for the care and use of laboratory animals were fllowed.Li,Xiumin Yan,Wei Zhao,Xueliang Zhu,and Jun Zhou declare that。
Dear Editor,O-GIcNAcylation is a nutrient sensor that is particularly sensitive to environmental glucose(Hardiville and Hart,2014).Glucose can be converted to UDP-GIcNAc through the hexosamine biosynthetic pathway,pro...
关键词：UDP RESIDUE REMOVE 
Phosphatidylinositol 4-kinase β is required for the ciliogenesis of zebrafish otic vesicle被引量：1
《Journal of Genetics and Genomics》2020年第10期627-636,共10页Yufei Feng Ping Yu Jingyu Li Ying Cao Jingjing Zhang 
supported by grants from the National Key R&D Program of China(2018YFA0801000)to J.Z.;the National Natural Science Foundation of China(31970777,31771628,31601165);Guangdong Natural Science Fund for Distinguished Young Scholars(2017A030306024)to J.Z
The primary cilium,an important microtubule-based organelle,protrudes from nearly all the vertebrate cells.The motility of cilia is necessary for various developmental and physiological processes.Phosphoinositides(PIs...
关键词：CILIOGENESIS Pi4kb Hair cell Hearing loss ZEBRAFISH 
Potential Application of TCM Sophoridine in Regulating Intensity of Autophagy to Treat PKD
《Medicinal Plant》2018年第4期97-101,106,共6页Guangqiang MA Yan LIN Hanfeng CUI Qinglong SHU Hongjiao WAN 
Supported by Project of Health and Family Planning Commission of Jiangxi Province(2014A027);Scientific and Technological Project of Jiangxi Provincial Department of Education(GJJ160843)"Study on Weight-reducing Effect and Mechanism of Coix Seed"
Nearly all cells have primary cilia( PC) composed of microtubules,primary cilia mainly functioning as sensing various signals of the environment and coordinating intracellular signaling pathways. Autophagy is an adapt...
关键词：AUTOPHAGY CILIOGENESIS CILIOPATHY Primary cilium 
The glial actin cytoskeleton regulates neuronal ciliogenesis被引量：1
《Cell Research》2017年第3期448-451,共4页Hao Zhu Lianwan Chen Yihong Yang Zhiwen Zhu Xianliang Zhang Wei Li Long Miao Yan Zhang Guangshuo Ou 
GO thanks Drs D Huangfu, G Jansen and M Bettencourt Dias for their discussions regarding this project. We also thank the staff members L Xiaomin of Tsinghua University Branch of China Na- tional Center for Protein Sciences （Beijing, China） for providing the facility support. This work was supported by the National Basic Research Program of China （973 Program; 2013CB945600 and 2012CB945002）, and the National Natural Science Foundation of China （31201048, 31222035, 31101002, 31100972, 31171295, 31190063 and 31501131）.
Dear Editor, Cilia are remarkable microtubule （MT）-based organelles that are essential for cell motility, sensory perception and signal transduction [1]. Ciliary defects have been implicated in various human diseas...
Emerging roles of NudC family： from molecular regulation to clinical implications被引量：5
《Science China(Life Sciences)》2016年第5期455-462,共8页Qiqin Fu Wei Wang Tianhua Zhou Yuehong Yang 
supported by the Ministry of Science and Technology of China (2012CB945004, 2013CB945603);Natural Scientific Foundation of China (31125017, 31190063, 31100975, 31301149, 31471259);the 111 Project (B13026)
Nuclear distribution gene C （NudC） was first found in Aspergillus nidulans as an upstream regulator of NudF, whose mamma- lian homolog is Lissencephaly 1 （Lisl）. NudC is conserved from fungi to mammals. Vertebrate...
关键词：nuclear distribution gene C heat shock protein 90 p23 DYNEIN Lissencephaly 1 cell cycle CILIOGENESIS 
全选清除导出
共2页<12>
检索报告 对象比较 聚类工具 使用帮助 返回顶部