the financial supports from the National Natural Science Foundation of China (No.20272021).
An efficient synthetic route to muurolane type sesquiterpenes starting from (R)-carvone, employing allylic diazene rearrangement and the ring closing methesis (RCM) reaction as key steps, is described. The first a...
3-Oxo-11,12,13-trihydroxyeudesm-4-ene(1) was a highly oxygenated natural eudesmane isolated from traditional herbal medicine with an antiphlogostic and spasmolytic activity.For the purpose of pharmacological activity ...
Supported by the National Natural Science Foundation of China(No20272021)
A highly efficient and convergent approach for the synthesis of octalone 1, the focal intermediate for the synthesis of several sesquiterpenoids, was developed based on the cationic cyclization strategy of the functio...
This work was financially supported by the National Natural Science Foundation of China (No 20272021).
The first total synthesis of natural 6β-cinnamoyloxy-1α-hydroxy-5, 10-bis-epi- eudesm-4-en-3-one (1), a highly complex natural eudesmane, was described.
The first total synthesis of (+)-5α-hydroxy-isopterocarpolone (1), an oxygenated eudesmane isolated from Chinese folk medicine Artemisia eriopoda, starting from (+)-dihydrocarvone(2) was described. Compound 4...
This work was financially supported by the National Natural Science Foundation of China(No.20272021).
A facile synthetic route to two seco-eudesmane, 4, 5-dioxo-10-epi-4, 5-seco-γ- eudesmane (1) and 4, 5-dioxo-10-epi-4, 5-seco-γ-eudesmol (2) from (+)-dihydrocarvone has been described. Avoiding expensive reagents, th...
(±)-1-Methyl-7-oxabicyclo[2.2.1]heptan-2-one (1) is a versatile chiral building block for terpenoids. It could be applied in total synthesis of eudesmanes, agarofurans and norcarotenoids. Compound (±)-1 was reduced ...