To investigate the effect of systemic administration dexmedetomidine, a selective alpha 2 adrenergic receptor (α2AR) agonist, on thermal hyperalgesia and spinal glial activation evoked by monoarthritis (MA). Meth...
supported by National Natural Science Fundation of China (No.30870835,30821002,and 30900444);National Basic Research Program of China (No. 2007CB512303,2007CB512502,and 2006CB500807);Postdoctoral Fundation of China (No.20080440578)
Objective To explore the role of the extracellular signal-regulated kinase (ERK)/cAMP response element binding protein (CREB) pathway in the induction of long-term potentiation (LTP) in the anterior cingulate co...