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国家重点基础研究发展计划(2010CB732602): 作品数：15被引量：50H指数：5; 导出分析报告; 相关作者：杨思华邢达黄茹许栋纪轩荣更多>>; 相关机构：华南师范大学更多>>; 相关期刊：《华南师范大学学报（自然科学版）》《Chinese Physics Letters》《Science Bulletin》《中国激光》更多>>; 相关主题：光声成像生物光学TRANSLOCATION现场可编程门阵列无损检测更多>>; 相关领域：医药卫生生物学理学机械工程更多>>

光声成像技术及其医学应用进展被引量：10: 《华南师范大学学报（自然科学版）》2016年第1期9-15,2,共7页曾礼漳杨思华邢达; 国家科技部重点基础研究973计划项目(2011CB910402,2010CB732602);教育部“长江学者与创新团队发展计划”项目(IRT0829); 光声成像技术是一种具有广泛应用前景的无损生物医学成像技术,其结合了纯光学成像高选择特性和纯超声成像中深穿透特性的优点,克服了光在组织中的高散射限制,实现了对活体深层组织的高分辨、高对比度成像.近年,光声成像技术得到了飞速发...; 关键词：光声成像高分辨率生物医学

Effects of LPLI on microglial phagocytosis in LPS-induced neuroinflammation model: 《Journal of Innovative Optical Health Sciences》2014年第3期1-10,共10页Sheng Song Wei Chen Feifan Zhou; supported by the National Basic Research Program of China(2011CB910402,2010CB732602);the Program for Changjiang Scholars and Innovative Research Team in University(IRT0829);the National Natural Science Foundation of China(30870676,30870658).; Microglial activation plays an important role in neurodegenerative diseases.Once activated,they have macrophage-like capabilities,which can be beneficial by phagocytosis and harmful by se-cretion of neurotoxins.Howeve...; 关键词：MICROGLIA PHAGOCYTOSIS LPLI Racl.

Photoactivation of GLUT4 translocation promotes glucose uptake via PI3-K/Akt2 signaling in 3T3-L1 adipocytes: 《Journal of Innovative Optical Health Sciences》2014年第3期12-21,共10页Lei Huang Longlong Gong Xiaoxiao Jiang Da Xing; supported by the National Basic Research Program of China(2011CB910402,2010CB732602);the Program for Changjiang Scholars and Innovative Research Team in Uni-versity(IRT0829);the National Natural Science Foundation of China(81101741).; Insulin resistance is a hallmark of the metabolic syndrome and type 2 diabetes.Dysfunction of PI-3K/Akt signaling was involved in insulin resistance.Glucose transporter 4(GLUT4)is a keyfactor for glucose uptake in mus...; 关键词：Glucose transporter 4 PI-3K/Akt low-power laser irradiation insulin resistance 3T3-L1 adipocytes type 2 diabetes.

CONTRAST-ENHANCED PHOTOACOUSTIC IMAGING USING INDOCYANINE GREEN-CONTAINING NANOPARTICLES被引量：1: 《Journal of Innovative Optical Health Sciences》2014年第1期19-25,共7页JUNPING ZHONG SIHUA YANG; supported by the National Basic Research Program of China(2011CB910402,2010CB732602);the Program for Changjiang Scholars and Innovative Research Team in University(IRT0829);the National Natural Science Foun-dation of China(81127004,11104087);the Foum-dation for Distinguished Young Talents in Higher Education of Guangdong,China(LYM10061);the Specialized Research Fund for the Doctoral Programof Higher Education(20114407120001);the Sci-ence and Technology Project of Guangzhou,China(2012J4100114).; Contrast agents are attracting a great deal of attention in photoacoustic inaging.Here weintroduce an exogenous contrast agent that provides high photoacoustic signal amplitude at thenear-infrared wavelength._Our_agen...; 关键词：Photoacoustic imaging NANOPARTICLE indocyanine green phospholipid-polyethyleneglycol.

Sensitive monitoring of RNA transcription levels using a graphene oxide fluorescence switch被引量：3: 《Chinese Science Bulletin》2013年第21期2634-2639,共6页ZHOU XiaoMing LIAO YuHui XING Da; supported by the National Basic Research Program of China (2010CB732602);the Key Program of NSFC-Guangdong Joint Funds of China (U0931005);the National Natural Science Foundation of China(81101121);the Natural Science Foundation of Guangdong Province(S2011040005386); Catalytic transfer of genetic information from DNA to RNA is very important in life activities. The unconventional RNA transcription level may be related to the source of genetic diseases. At present, conventional met...; 关键词：RNA聚合酶转录水平荧光开关氧化石墨监测氧化物单链DNA 检测平台

荧光相关光谱在生物化学领域中的应用被引量：1: 《激光生物学报》2013年第4期289-293,共5页黄茹周小明; 科技部国家重点基础研究973计划项目(2010CB732602);教育部"长江学者与创新团队计划"创新团队项目(IRT0829);国家自然科学基金项目(81101121);国家自然科学基金--广东联合基金重点项目(U0931005);华南师范大学研究生科研创新基金(2012kyjj220); 荧光相关光谱(fluorescence correlation spectroscopy,FCS)是一种通过监测荧光涨落从而获得单分子水平的分子扩散行为信息的技术。FCS高灵敏度的优点使得它已发展成为一种可以在活体外与活体内检测分子浓度、扩散系数、结合和解离常数...; 关键词：荧光相关光谱分子诊断生物化学

基于特征基因识别的食源性致病微生物快速检测技术新进展被引量：5: 《科学通报》2013年第11期961-971,共11页朱啸黄茹邢达; 国家自然科学基金-广东联合基金重点项目(U0931005);国家自然科学基金(81101121);国家重点基础研究计划(2010CB732602);教育部"长江学者与创新团队计划"创新团队项目(IRT0829)资助; 目前,由食源性致病微生物引发的食品安全问题备受社会的关注.基于特征基因识别的食源性致病微生物的检测方法,由于其识别对象在体外具有稳定且易于扩增等优点,因而特异性和灵敏度较好,其应用范围也越来越广泛.本文综述了近些年基于特征...; 关键词：基因识别食源性致病微生物快速检测电化学发光微流控

MICROW AVE-INDUCED THERMOA COUSTIC IMAGING FOR EARLY BREAST CA NCER DETECTION被引量：1: 《Journal of Innovative Optical Health Sciences》2013年第1期38-43,共6页ZHONG JI YONG FU SIHUA YANG; supported by the National Basic Research Program of China(2011CB910402,2010CB732602);the Program for Changjiang Scho-lars and Innovative Research Team in University(IRT0829);the National Natural Science Foun-dation of China(81127004,11104087);the Foun-dation for Distinguished Young Talents in Higher Education of Guangdong,China(LYM10061);the Specialized Research Fund for the Doctoral Program of Higher Education(20114407120001);the Science and Technology Project of Bejing,China(2012J4100114).; Microwave induced thermoacoustic tomography(TAT)is a noninvasive,nonionizing modality based on the inherent differences in microwave absorpt ion of malignant breast tissues and normal adipose dominated breast tissues....; 关键词：Early breast cancer microwave induced thermoacoustic tomography dielectric properties

REAL-TIME FLUORESCENCE IMAGING OF SIRT1 CYTOSOLIC TRANSLOCATION UNDER THE TREATMENT OF GROWTH FACTOR DEPRIVATION: 《Journal of Innovative Optical Health Sciences》2011年第2期133-141,共9页CHENGBO MENG SHENGNAN WU DA XING; The authors thank Prof.Yoshiyuki Horio for providing the plasmid SIRT1-EGFP.This research is supported by the National Basic Research Program of China(2010CB732602,2011CB910402);the Program for Changjiang Scholars and Innovative Research Team in University(IRT0829);the National Natural Science Foundation of China(30870676,30870658).; Sirtuins comprise a family of enzymes implicated in the determination of organismal lifespan in yeast and the nematode.Human sirtuin SIRT1 has been shown to deacetylate several proteins in a NADt-dependent manner.It i...; 关键词：Senescence growth factor starvation SIRT1

基于多通道并行采集的光声成像系统被引量：16: 《中国激光》2011年第2期126-131,共6页许栋向良忠纪轩荣邢达(指导); 国家973计划(2010CB732602);教育部长江学者与创新团队发展计划(IRT0829);国家自然科学基金(30627003,30870676);广东省自然科学基金(7117865);广东高校优秀青年创新人才培养计划(LYM09055)资助课题; 设计了一套基于多通道并行采集的快速光声成像系统,包括超声探测器、多通道并行采集系统、短脉冲激光器、计算机组成的硬件平台,并开发了配套的上位机软件来控制系统的采集和实时成像。多通道并行采集系统包括前端模拟放大、抗混叠滤波...; 关键词：生物光学光声成像系统多通道并行采集现场可编程门阵列无损检测

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