云南高校图书馆联盟文献共享服务平台- 国家自然科学基金(81072152)

国家自然科学基金(81072152): 作品数：37被引量：162H指数：8; 导出分析报告; 相关作者：冯茂辉谢伟苏飞陈双倩王国洲更多>>; 相关机构：武汉大学通城县人民医院湖北省水果湖高级中学中国人民解放军中部战区总医院更多>>; 相关期刊：《Current Medical Science》《中华实用诊断与治疗杂志》《中华临床医师杂志（电子版）》《中华实验外科杂志》更多>>; 相关主题：META分析胃癌蛋白结直肠癌腹腔镜更多>>; 相关领域：医药卫生更多>>

Identification of Prognostic Genes for Colon Cancer through Gene Coexpression Network Analysis被引量：1: 《Current Medical Science》2021年第5期1012-1022,共11页Dan-wen WANG Zhang-shuo YANG Jian XU Li-jie YANG Tie-cheng YANG Hua-qiao WANG Mao-hui FENG Fei SU; supported in part by grants from the National Natural Science Foundation of China(No.81072152 and No.81770283);Natural Science Foundation of Hubei Province(No.2015CFA027);Research Foundation of Health and Family Planning Commission of Hubei Province(No.WJ2015MAO10 and No.WJ2017M249);Clinical Medical Research Center of Peritoneal Cancer of Wuhan(No.2015060911020462);Subsidy Project of No.1 Hospital of Lanzhou University(No.Idyyyn2018-13);Innovation fund of universities in Gansu Province(No.2020B-009).; Objective:The present study was aimed to identify novel key genes,prognostic biomarkers and molecular pathways implicated in tumorigenesis of colon cancer.Methods:The microarray data GSE41328 containing 10 colon cance...; 关键词：colon cancer biomarkers weighted gene co-expression network analysis prognosis pathological stage

Expression of Stanniocalcin 2 in Breast Cancer and Its Clinical Sigmiicance被引量：3: 《Current Medical Science》2019年第6期978-983,共6页Shu-ting JIANG Hua-qiao WANG Tie-cheng YANG Dan-wen WANG Li-jie YANG Yi-qing XI Fan-zheng KONG Xue-kai PAN Li-hua XU Mao-hui FENG Wei XIE Fei SU; grants from National Natural Science Foundation of China(No.81072152 and No.81770283);Natural Science Foundation of Hubei Province(No.2015CFA027);Research Foundation of Health and Family Planning Commission of Hubei Province(No.WJ2015MA010 and No.WJ2017M249);Clinical Medical Research Center of Peritoneal Cancer of Wuhan(No.2015060911020462);Subsidy Project of No.1 Hospital of Lanzhou University(No.Idyyyn2018-13);Research Foundation of Health and Family Planning Commission of Changzhou(No.QN201824).; This study aims to explore the expression of stanniocalcin 2(STC2)gene in breast cancer and its clinical significance.Female patients with breast cancer from Zhongnan Hospital of Wuhan University admitted during March...; 关键词：stanniocalcin 2 breast cancer real-time quantitative polymerase chain reaction METASTASIS

血管内皮生长因子与胃癌关系的研究进展被引量：17: 《中华实用诊断与治疗杂志》2019年第11期1131-1134,共4页黄明亮赵达胡玉萍翁乾淋冯茂辉杨丽平苏飞; 国家自然科学基金(81770283);国家自然科学基金(81072152);武汉市腹膜癌临床医学研究中心资助项目(2015060911020462);兰州大学第一医院院内项目(ldyyn2018-13);甘肃卫生行业科研计划管理项目(GWGL2010-20); 血管内皮生长因子(vascular endothelial growth factor,VEGF)是最具特征的血管新生调节因子,与肿瘤的生长、浸润、转移密切相关,是肿瘤诊断、靶向治疗以及预后评估的研究热点。近年来,VEGF在胃癌中作用的研究较多。本文就VEGF与胃癌发...; 关键词：胃癌血管内皮生长因子血管内皮生长因子受体

3D腹腔镜Roux-en-Y胃旁路术与袖状胃切除术治疗肥胖症合并2型糖尿病临床疗效的比较被引量：19: 《中华实验外科杂志》2019年第1期134-137,共4页汪波杨丽洁杨张朔王丹雯习一清冯茂辉马丹丹傅涛蔡逊; 国家自然科学基金面上项目(81770283、81072152);湖北省自然科学基金面上项目(2015CFA027);湖北省卫生与计划生育委员会科研基金面上项目(WJ2015MA010、WJ2017M249、WJ2017H0048、WJ2017I-10043);武汉市腹膜癌临床医学研究中心项目(2015060911020462).; 目的对比分析腹腔镜Roux-en-Y胃旁路术(LRYGB)和腹腔镜袖状胃切除术(LSG)治疗肥胖症合并2型糖尿病(T2DM)的可行性、安全性及临床疗效。方法收集我院收治的48例肥胖症合并T2DM患者资料。按照手术方式分为LRYGB组和LSG组。术后随访1年,对...; 关键词：肥胖症 2型糖尿病 ROUX-EN-Y胃转流术袖状胃切除术临床疗效腹腔镜

DJ-1 Alters Epirubicin-induced Apoptosis via Modulating Epirubicin-activated Autophagy in Human Gastric Cancer Cells被引量：3: 《Current Medical Science》2018年第6期1018-1024,共7页Xue-kai PAN Fei SU Li-hua XU Zhang-shuo YANG Dan-wen WANG Li-jie YANG Fan-zheng KONG Wei XIE Mao-hui FENG; grants from the National Natural Science Foundation of China(No.81072152 and No.81770283);Natural Science Foundation of Hubei Province(No.2015CFA027);Research Foundation of Health and Family Planning Commission of Hubei Province(No.WJ2015MA010 and No.WJ2017M249);Clinical Medical Research Center of Peritoneal Cancer of Wuhan (No.2015060911020462).; Epirubicin,which is a conventional chemotherapeutic drug for gastric cancer,has innate and adaptive chemoresistance.Recent studies revealed that epirubicin could induce autophagy as a defensive mechanism in drug resis...; 关键词：EPIRUBICIN gastric cancer DJ-1 apoptosis AUTOPHAGY

3D腹腔镜袖状胃切除术治疗肥胖症合并2型糖尿病的临床疗效及机制被引量：10: 《中华实验外科杂志》2018年第12期2310-2313,共4页汪波王丹雯习一清杨丽洁杨张朔冯茂辉马丹丹傅涛蔡逊; 国家自然科学基金面上项目(81770283、81072152);湖北省自然科学基金面上项目(2015CFA027);湖北省卫生计生委科研基金面上项目(WJ2015MA010、WJ2017M249、WJ2017H0048、WJ2017H0043);武汉市腹膜癌临床医学研究中心项目(2015060911020462)。; 目的探讨3D腹腔镜袖状胃切除术(LSG)治疗肥胖症合并2型糖尿病(T2DM)的安全性、可行性、临床疗效及对胰高血糖素样肽1(GLP-1)和胃饥饿素(Ghrelin)水平的影响。方法我院收治的26例肥胖症合并T2DM患者均由同一手术团队施行3D腹腔镜袖状胃...; 关键词：3D腹腔镜 2型糖尿病袖状胃切除术临床疗效胃饥饿素

三野淋巴结清扫术在食管癌手术中的应用被引量：4: 《中华实验外科杂志》2018年第5期981-983,共3页陶浩冉杨嘉仪潘雪凯杨张朔习一清王昕徐利华孔繁政吴洲清陈家宽谢伟冯茂辉; 国家自然科学基金（81072152、81770283）;湖北省自然科学基金（2015CFA027）;湖北省卫生计生科研基金（WJ2015MA010、WJ2017M249）;武汉市腹膜癌临床医学研究中心资助项目（2015060911020462）; 食管癌是常见恶性肿瘤之一,尽管多学科治疗手段提高了食管癌的预后,但其病死率仍较高,因为食管癌淋巴结转移可首先出现在颈部至腹部,所以采取了扩大淋巴结清扫的策略;三野淋巴结清扫术（3FLD）建立于20世纪80年代的日本,定义为一种经胸...; 关键词：食管癌淋巴结转移三野淋巴结清扫术

Knockdown of GRHL3 Inhibits Activities and Induces Cell Cycle Arrest and Apoptosis of Human Colorectal Cancer Cells被引量：2: 《Journal of Huazhong University of Science and Technology(Medical Sciences)》2017年第6期880-885,共6页王小康周芬芳陶浩冉王昕张弛苏飞王诗培徐利华潘雪凯冯茂辉谢伟; supported by grants from National Natural Science Foundation of China(No.81072152);Natural Science Foundation of Hubei Province(No.2015CFA027);Research Foundation of Health and Family Planning Commission of Hubei Province(No.WJ2015MA010 and No.WJ2017M249);Clinical Medical Research Center of Peritoneal Cancer of Wuhan(No.2015060911020462); The Grainyhead-like 3（GRHL3） is involved in epidermal barrier formation, neural tube closure and wound repair. Previous studies have suggested that GRHL3 has been linked to many different types of cancers. However, ...; 关键词：Grainyhead-like 3 colorectal cancer proliferation migration cell cycle apoptosis

汉黄芩素对肝癌细胞SMMC-7721增殖、迁移及侵袭的影响被引量：8: 《中华实用诊断与治疗杂志》2017年第8期735-738,共4页苏飞赵达庄亚飞潘雪凯周芬芳冯茂辉; 国家自然科学基金(81072152);湖北省自然科学基金(2015CFA027);湖北省卫生计生委科研基金(WJ2015MA010); 目的探讨汉黄芩素对肝癌细胞SMMC-7721增殖、迁移及侵袭能力的影响。方法肝癌细胞SMMC-7721分为5μmol/L汉黄芩素组、10μmol/L汉黄芩素组、20μmol/L汉黄芩素组和空白对照组。5、10、20μmol/L汉黄芩素组分别加入5、10、20μmol/L汉黄...; 关键词：肝癌汉黄芩素增殖迁移侵袭

Inhibition of Adhesion and Metastasis of HepG2 Hepatocellular Carcinoma Cells In Vitro by DNA Aptamer against Sialyl Lewis X被引量：1: 《Journal of Huazhong University of Science and Technology(Medical Sciences)》2017年第3期343-347,共5页王小康彭艳陶浩冉周芬芳张弛苏飞王诗培刘庆徐利华潘雪凯谢伟冯茂辉; supported by grants from the National Natural Science Foundation of China(No.81072152);the Natural Science Foundation of Hubei Province(No.2015CFA027);the Research Foundation of Health and Family Planning Commission of Hubei Province(No.WJ2015MA010);the Clinical Medical Research Center of Peritoneal Cancer of Wuhan(No.2015060911020462); The sialyl Lewis X（SLe;） antigen encoded by the FUT7 gene is the ligand of endotheliam-selectin（E-selectin）. The combination of SLe;antigen and E-selectin represents an important way for malignant tumor metastasis...; 关键词：sialyl Lewis X DNA aptamer hepatocellular carcinoma METASTASIS

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