supported by the National Natural Science Foundation of China(21101091,31370812);the Scientific Research Foundation for the Returned Overseas Chinese Scholars,Ministry of Education of China.J.Wang is supported by the National Basic Research Program of China(2010CB912301,2009CB82 5505);the National Natural Science Foundation of China(90913022);Y.Lu is supported by the US National Institute of Health(GM062211)
Rational protein design is a powerful strategy,not only for revealing the structure and function relationship of natural metalloproteins,but also for creating artificial metalloproteins with improved properties and fu...
supported by the National Natural Science Foundation of China,NSFC(No.21101091);Hunan Provincial Natural Science Foundation(No.11JJ4017);Hunan Provincial Education Foundation(No.11B105);the initial foundation for oversea scholar return to University of South China(No.2011XQD16)
By retaining the native distal His64 in sperm whale myoglobin (Mb), a second distal histidine was engineered in Mb by mutating Leu29 to His29. The resultant mutant of L29H Mb exhibits an unusual enhanced peroxidase ...