REDUCTASE

作品数：211被引量：556H指数：11
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In vivo functional analysis of the cotton bollworm Helicoverpa armigera 24-dehydrocholesterol reductase(HaDHCR24)in phytosterol metabolism
《Insect Science》2025年第2期398-408,共11页Zhen Yang Jinchan Ren Shuning Lu Yuanze Feng Yongliang Fan Tong-Xian Liu Xiangfeng Jing 
supported by funds awarded to X.J.by the National Natural Science Foundation of China(32070506&32372542).
Insects have to obtain sterols from food due to the inability to synthesize this essential nutrient de novo.For lepidopteran insects,they can convert a variety of phytosterols into cholesterol to meet their growth nee...
关键词：AMIODARONE CRISPR/Cas9 DESMOSTEROL DHCR24 Helicoverpa armigera 
Proline metabolism is essential for alkaline adaptation of Nile tilapia(Oreochromis niloticus)
《Journal of Animal Science and Biotechnology》2025年第2期714-728,共15页Minxu Wang Yuxi Yan Wei Liu Jinquan Fan Erchao Li Liqiao Chen Xiaodan Wang 
supported by grants from the National Natural Science Foundation of China(No.32172946);the Young Elite Scientists Sponsorship Program by CAST(2022QNRC001);the Shanghai Rising-Star Program(2022);the Fundamental Research Funds for the Central Universities,ECNU。
Background Saline-alkaline water aquaculture has become a key way to mitigate the reduction of freshwater aquaculture space and meet the increasing global demand for aquatic products.To enhance the comprehensive utili...
关键词：Alkalinity stress Oreochromis niloticus Oxidative stress Proline metabolism Pyrroline-5-carboxylate reductase 
Effect of cholesterol metabolism on hepatolithiasis
《World Journal of Gastroenterology》2025年第1期157-162,共6页Lin Zheng Zi-Yu Ye Jun-Ji Ma 
Supported by Hebei Natural Science Foundation,No.H2022206539;Hebei Provincial Government Funded Clinical Talents Training Project,No.ZF2023143.
Surgical intervention is currently the primary treatment for hepatolithiasis;how-ever,some patients still experience residual stones and high recurrence rates after surgery.Cholesterol metabolism seems to play an impo...
关键词：HEPATOLITHIASIS Cholesterol metabolism High-fat diet 3-hydroxy-3-methylglutaryl-coenzyme A reductase Interlobular bile duct 
Enantioselective biosynthesis of vicinal diamines enabled by synergistic photo/biocatalysis consisting of an ene-reductase and a green-light-excited organic dye
《Chinese Journal of Catalysis》2025年第1期223-229,共7页Fengming Shi Bin Chen Jinhai Yu Ruiqi Zhu Yu Zheng Xiaoqiang Huang 
国家自然科学基金(22277053);国家重点研发计划(2022YFA0913000);江苏省自然科学基金项目(BK20220760);南京大学卓越计划(ZYJH004)。
Vicinal diamines are key motifs widely-found in many pharmaceuticals and biologically active molecules.An appealing approach for synthesizing these molecules is the amination of enamines,but few examples have been exp...
关键词：Photobiocatalysis Vicinal diamines Asymmetric synthesis HYDROAMINATION Green light excitation 
Regulatory Mechanism of Xiaozheng Tongluo Method on Hepatic Lipid Metabolism in ApoE^(-/-) Mice:Insights from the Sterol Regulatory Element-binding Protein-2/3-hydroxy-3-methylglutaryl Coenzyme A Reductase/Low-density Lipoprotein Receptor Signaling Pathwa
《World Journal of Traditional Chinese Medicine》2024年第3期363-369,共7页Xin Zhang Jian-Li Ge Kun Su Jian-Ming He Min-Mei Zhang Jing Zhang Yun-Long Ma Yun-Chao Sun Xin-Qiang Chu 
supported by the Science and Technology Support Program Project of the Hebei Provincial Department of Science and Technology (No. 19277753D);the Scientific Research Project of the Hebei Administration of TCM (No. 2019004, No. 2019066)
Objective: The objective of the study was to explore the regulatory mechanism of the Xiaozheng Tongluo method on lipid metabolism in liver tissue based on the sterol regulatory element-binding protein-2/(SREBP2)/3-hyd...
关键词：ApoE^(‑/‑)mice lipid metabolism liver sterol regulatory element‑binding protein‑2/3‑hydroxy‑3‑methylglutaryl coenzyme a reductase/low‑density lipoprotein receptor signaling pathway Xiaozheng Tongluo method 
OsFK1 encodes C-14 sterol reductase,which is involved in sterol biosynthesis and affects premature aging of leaves in rice
《The Crop Journal》2024年第4期1010-1021,共12页Ping Li Xia Zhang Wuzhong Yin Yang Shui Jie Zhang Nana Xu Dasong Bai Qingxiong Huang Yuanyuan Li Pan Qi Xing Li Qianlong Li Shihong Yang Guotao Yang Hong Chen Peng Qin Yungao Hu Youlin Peng 
supported by the National Natural Science Foundation of China(32001491,32360493);Natural Science Foundation of Sichuan Province(2022NSFSC0153,2022NSFSC1754,2023NSFSC1170);the Key Research and Development Program of Sichuan Province(2021YFYZ0016).
The enzyme C-14 sterol reductase is involved in biosynthesis of brassinosteroids(BR)and sterols,as well as plant development.OsFK1,a member of the sterol biosynthesis pathway located in the endoplasmic reticulum(ER),e...
关键词：Leaf development ROS Phytosterol biosynthesis RICE 
Identification of 3-ketocapnine reductase activity within the human microbiota
《mLife》2024年第2期307-316,共10页Xiaotong Wu Lukuan Hou Haili Zhang Yi Ma Jufang Wang Mingwei Cai Xiaoyu Tang 
supported by the Shenzhen Bay Laboratory Startup Funds(21230051 to X.T.);Guangdong Province's Pearl River Recruitment Program of Talents(2021QN02Y855 to X.T.);GuangDong Basic and Applied Basic Research Foundation(2021A1515110334 to M.C.);the Natural Science Basic Research Plan in Shaanxi Province of China(2023-JC-QN-0160 to L.H.);the Scientific Research Foundation of Northwest A&F University(Z1090122052 to L.H.).
The microbial synthesis of sulfonolipids within the human body is likely involved in maintaining human health or causing diseases.However,the enzymes responsible for their biosynthesis remain largely unknown.In this s...
关键词：3-ketocapnine reductase capnines human microbiota sulfonolipids 
Transcriptome-wide analysis of PIP reductase gene family identified a phenylpropene synthase crucial for the biosynthesis of dibenzocyclooctadiene lignans in Schisandra chinensis
《Synthetic and Systems Biotechnology》2024年第1期78-87,共10页Tingyan Qiang Yu Chen Bin Li Yuqing Dong Xueping Wei Jiushi Liu Bengang Zhang Haitao Liu Peigen Xiao 
supported by grants from the National Natural Science Foundation of China(No.82204576);the CAMS Innovation Fund for Medical Sciences(CIFMS)(No.2022-I2M-JB-009).
Phenylpropenes,such as isoeugenol and eugenol,are produced as defend compounds,floral attractants,and flavor constituents by phenylpropene synthases belonging to the PIP reductase family.Moreover,isoeugenol is propose...
关键词：Schisandra chinensis(Turcz.)baill. Dibenzocyclooctadiene lignans PIP reductase family Phenylpropenes Isoeugenol synthase 
Statin, aspirin and metformin use and risk of hepatocellular carcinoma related outcomes following liver transplantation: A retrospective study
《World Journal of Transplantation》2024年第3期120-131,共12页William Chung Kevin Wong Noel Ravindranayagam Lauren Tang Josephine Grace Darren Wong Danny Con Marie Sinclair Avik Majumdar Numan Kutaiba Samuel Hui Paul Gow Vijayaragavan Muralidharan Alexander Dobrovic Adam Testro 
This study was approved by the Austin Health Human Ethics Research Committee(No.HREC/87459/Austin-2022).
BACKGROUND Liver transplantation(LT)is a potentially curative therapy for patients with hepatocellular carcinoma(HCC).HCC-recurrence following LT is associated with reduced survival.There is increasing interest in che...
关键词：Liver transplantation Hepatocellular carcinoma Transplant oncology STATINS HMG-Co-A reductase ASPIRIN METFORMIN Mammalian target of rapamycin 
Effect of tillage state of paddy soils with heavy metal pollution on the nosZ gene of N_(2)O reductase被引量：1
《Journal of Environmental Sciences》2024年第3期469-477,共9页Liping Jiang Shiguang Liu Shanyun Wang Libo Sun Guibing Zhu 
supported by the National Natural Science Foundation of China (Nos.91851204 and 92251304);the Excellent Innovation Project of Research Center for EcoEnvironmental Sciences,Chinese Academy of Sciences (No.RCEES-EEI-2019-02);the Program of the Youth Innovation Promotion Association of Chinese Academy of Sciences。
Paddy soils are an important source of atmospheric nitrous oxide(N_(2)O).However,numerous studies have focused on N_(2)O production during the soil tillage period,neglecting the N_(2)O production during the dry fallow...
关键词：Pappy soils N_(2)O reductase nosZ gene Heavy-metal pollution 
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