Supported by National Natural Science Foundation of China(No.81160528);Administration of Traditional Chinese Medicine of Guizhou Province foundation,China(No.2009-79)
Objective: To investigate the effect and potential mechanisms of rutaecarpine (Rut) in a rat artery balloon-injury model. Methods: The intimal hyperplasia model was established by rubbing the endothelia with a bal...
Supported by the National Natural Science Foundation of China(No.81160528);Foundation of Administration of Traditional Chinese Medicine of Guizhou Province(No.2009-79)
Objective: To investigate the effects of evodiamine(Evo), a component of Evodiaminedia rutaecarpa(Juss.) Benth, on cardiomyocyte hypertrophy induced by angiotensin Ⅱ(Ang Ⅱ) and further explore the potential mechanis...
Supported by the National Natural Science Foundation of China(No.81160528);the Governor Foundation of Guizhou Province(No.2006-07);Administration of Traditional Chinese Medicine of Guizhou Province Foundation(No.2009-79)
Objective: To evaluate the effects and possible mechanisms of rutaecarpine on angiotensin Ⅱ (Ang Ⅱ )-induced proliferation in cultured rat vascular smooth muscle cells (VSMCs). Methods: VSMCs were isolated fro...