CALCINEURIN

作品数:131被引量:471H指数:12
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相关领域:医药卫生生物学更多>>
相关作者:魏群骆静李满祥朱洁李泽庚更多>>
相关机构:北京师范大学哈尔滨医科大学北京大学南京师范大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划湖北省自然科学基金国家教育部博士点基金更多>>
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Ca^(2+)-induced CpCBL8-CpCIPK9 module negatively regulates dormancy breaking and cold tolerance in winter-flowering wintersweet
《Horticultural Plant Journal》2025年第2期877-890,共14页Mingkang Tian Qiang Li Ning Liu Juncai Li Juntao Huo Shunzhao Sui Zhineng Li 
funded by the Natural Science Foundation of Chongqing(CSTB2023NSCQ-MSX0236);Fundamental Research Funds for the Central Universities(SWU-XDJH202308);Earmarked Funds for the China Agriculture Research System(CARS-26)。
The complex of calcineurin B-like protein(CBL)and CBL-interacting protein kinase(CIPK)serves as key components in calcium-sensing,orchestrating various signals crucial for plant growth,development,and responses to bio...
关键词:Chimonanthus praecox CA^(2+) Calcineurin B-like protein(CBL) CBL-interacting protein kinase(CIPK) Flower development Cold stress response 
Tuning beneficial calcineurin phosphatase activation to counterα-synuclein toxicity in a yeast model of Parkinson’s disease
《Neural Regeneration Research》2025年第1期199-200,共2页Srishti Chawla Mikael Molin Thomas Nystrom 
Calcineurin(CN)is a calcium-and calmodulindependent serine/threonine that has been studied in many model organisms including yeast,filamentous fungi,plants,and mammals.Its biological functions range from ion homeostas...
关键词:ACTIVATION DINUCLEAR CONSERVED 
Cav3.2 channel regulates cerebral ischemia/reperfusion injury:a promising target for intervention被引量:2
《Neural Regeneration Research》2024年第11期2480-2487,共8页Feibiao Dai Chengyun Hu Xue Li Zhetao Zhang Hongtao Wang Wanjun Zhou Jiawu Wang Qingtian Geng Yongfei Dong Chaoliang Tang 
supported by the Natural Science Foundation of Anhui Province of China,No.2208085Y32;Scientific Research Plan Project of Anhui Province of China,No.2022AH020076;the Chen Xiao-Ping Foundation for the Development of Science and Technology of Hubei Province,No.CXPJJH12000005-07-115(all to CT).
Calcium influx into neurons triggers neuronal death during cerebral ischemia/reperfusion injury.Various calcium channels are involved in cerebral ischemia/reperfusion injury.Cav3.2 channel is a main subtype of T-type ...
关键词:CALCINEURIN Cav3.2 channel cerebral ischemia/reperfusion hippocampus HYPOXIA/REOXYGENATION inflammatory response nuclear factor of activated T cells 3 oxidative stress primary hippocampal neurons stroke 
Orai1过表达激活Calcineurin/TFEB通路对帕金森病细胞模型自噬及细胞活性的影响
《中国神经免疫学和神经病学杂志》2024年第5期343-351,共9页侯萌 王昭君 张皓洁 樊泽新 王荔 
山西省自然科学基金面上项目(20210302123288);山西省卫生健康委科研课题面上项目(2021064)。
目的研究钙释放激活钙通道调节分子1(calcium release-activated calcium modulator 1,Orai1)蛋白过表达激活钙调神经磷酸酶(Calcineurin,CaN)/转录因子EB(transcription factor EB,TFEB)通路对帕金森病(Parkinson disease,PD)细胞模型...
关键词:Orai1 Calcineurin/TFEB 自噬 帕金森病 多巴胺能神经元 
Exogenous Beta-guanidinopropionic acid administration enhances electromyostimulation-induced mitochondrial biogenesis in rat skeletal muscle
《Translational Exercise Biomedicine》2024年第3期295-304,共10页Naoki Fukao Junya Takegaki Ryo Takagi Koki Okumura Satoshi Fujita 
supported by JSPS KAKENHI Grant Number JP21KK0177 to SF.
Objectives Exercise training induces several skeletal muscle adaptations.Beta-guanidinopropionic acid(β-GPA)is a creatine analog that simulates the effect of exercise to induce mitochondrial biogenesis.However,the ef...
关键词:PGC-1Α AMPK OXPHOS CALCINEURIN muscle proteolysis 
The Ca^(2+)/CaN/ACC and cAMP/PKA/HK signal pathways are required for PBAN-mediated sex pheromone biosynthesis in Conogethes punctiferalis
《Journal of Integrative Agriculture》2024年第8期2735-2751,共17页Yao Zhang Zelong She Ruolan He Shuangyan Yao Xiang Li Xiaoguang Liu Xinming Yin Jizhen Wei Mengfang Du Shiheng An 
supported by the National Natural Science Foundation of China(31970472,32272547);the National Science Fund of Henan Province for Distinguished Young Scholars,China(202300410191);the Basic Research Project of the Key Scientific Research Projects of Universities in Henan Province,China(21zx013);the Henan Agricultural Research System,China(HARS-2209-G3);the Henan Special Support for High-Level Talents Central Plains Science and Technology Innovation Leading Talents,China(224200510018);the earmarked fund for China Agricultural Research System(CARS-27)。
Conogethes punctiferalis is a crop and fruit pest that has caused serious economic losses to agricultural production.This pest relies heavily on its sex pheromone to ensure sexual encounters and subsequent mating succ...
关键词:Conogethes punctiferalis sex pheromone CAMP/PKA CALCINEURIN acetyl-CoA carboxylase HEXOKINASE 
Stress enhances expression of calcium-binding proteins and NMDAR subunit genes in the rat hippocampus
《Neuroprotection》2024年第2期167-178,共12页Aravind Parthasarathy Ramesha Hanumanthappa Sarojini R.Bulbule Kiran P.C. Hemalatha Nanjaiah Gopinath G. Siddaiah B.M. David Muniswamy Devaraju Kuramkote Shivanna 
DST-SERB,NewDelhi,Grant/Award Number:SB/EMEQ-238/2013。
Backgrounds:Oxidative stress impairs the function of calcium-binding proteins and deregulates calcium signaling in living organisms.We have previously explored the overexpression of calcium-binding protein genes in a ...
关键词:CALCINEURIN H_(2)O_(2) HIPPOCAMPUS IMMOBILIZATION NMDA receptors 
Inhibiting 5-hydroxytryptamine receptor 3 alleviates pathological changes of a mouse model of Alzheimer's disease被引量:1
《Neural Regeneration Research》2023年第9期2019-2028,共10页Li-Fen Liu Yu-Tong Liu Dan-Dan Wu Jie Cheng Na-Na Li Ya-Ni Zheng Liang Huang Qiong-Lan Yuan 
supported by the Notional Natural Science Foundation of China,Nos.81371213 and 8107098 7;the Natural Science Foundation of Shanghai,No.21ZR1468400 (all to QLY)。
Extracellular amyloid beta(Aβ) plaques are main pathological feature of Alzheimer’s disease.However,the specific type of neuro ns that produce Aβ peptides in the initial stage of Alzheimer’s disease are unknown.In...
关键词:5-hydroxytryptamin receptor 3 Alzheimer’s disease amyloid beta plaques CALCINEURIN cognitive deficits HTR3 interneurons iCa2+ nuclear factor of activated T-cells transgenic amyloid precursor protein and presenilin-1 mice TROPISETRON 
miR-499通过抑制calcineurin抑制缺血/再灌注心肌细胞的凋亡被引量:2
《山西医科大学学报》2023年第7期932-938,共7页吴静 聂祖琼 尹琬凌 
武汉市卫生计生委科研计划资助项目(WX21C17)。
目的 探讨miR-499对钙调磷酸酶(calcineurin,CaN)的调控作用以及在缺血/再灌注(ischemia/repefusion,I/R)损伤心肌细胞中的作用机制。方法 将大鼠心肌细胞H9c2分成6组:对照组、I/R组、I/R+mimics组(转染miR-499 mimics后构建I/R细胞模型...
关键词:miR-499 钙调磷酸酶 缺血/再灌注 凋亡 心肌细胞 
A Brachypodium distachyon calcineurin B-like protein-interacting protein kinase,BdCIPK26,enhances plant adaption to drought and high salinity stress
《BIOCELL》2023年第5期1145-1158,共14页QINGCHEN LUO JIALU FENG XIUQI DENG 
funded by the Natural Science Foundation of Hubei Province,China(2019CFB388);the Guiding Project of Scientific Research Plan of the Hubei Provincial Department of Education(B2022007).
As sessile organisms,plants possess a complex system to cope with environmental changes.Ca^(2+)functions as a vital second messenger in the stress signaling of plants,and the CBL-interacting protein kinases(CIPKs)serv...
关键词:Brachypodium distachyon Abiotic stress CIPK ABA 
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