This work was supported by a grant from the National Natural Science Foundation of China (30571844 and 30571808) Acknowledgements We thank Drs. John Price, Joseline Ojaimi, and Jessica Vieusseux (Monash University, Melbourne, Australia) for their helpful advice. We thank Dr. Yan Zhang (School of Medicine, Shandong University, China) for kindly providing the recombinant adenoviruses.
Ornithine decarboxylase (ODC), the rate-limiting enzyme in polyamine biosynthesis that decarboxylates ornithine to putrescine, has become a promising target for cancer research. The aim of this study is to investiga...