supported by the Natural Science Foundation of Beijing Municipality(L222074);Key R&D Program of Shandong Province,China(2019JZZY011011).
Dear Editor,Patients undergoing allogeneic hematopoietic stem cell transplantation(HSCT)often experience a significant reduction in immune function due to factors such as severe lymphopenia,immunosuppressive treatment...
supported by the National Natural Science Foundation of China(No.82104289);the Yuandu Scholar Grant of Weifang City(Shandong,China)to JJL;the Shandong Provincial Health Commission of China(No.M2022053)。
Genetic mutations in TP53 contribute to human malignancies through various means.To date,there have been a variety of therapeutic strategies targeting p53,including gene therapy to restore normal p53 function,mutant p...
Emphysematous gastritis(EG)is a rare form of gastritis characterized by gastric wall pneumatosis.It is associated with a high mortality rate.Our case report describes a patient with a history of atrial fibrillation tr...
Enteric viral pathogens are responsible for numerous epidemics associated with the consumption of fresh fruit and vegetable, whether raw or minimally processed. The aim of the present study was to assess agricultural ...
Laboratory wastewater has been suggested as an important escape route for microorganisms from research environments.Likely reasons for the unintentional release of laboratory organisms are shortcomings in the handling...
This study was supported by the National Natural Science Foundation of China(82072264,81970003);Natural Science Foundation of Guangdong Province,China(2021A1515011071);The study sponsors had no involvement in the study design,in the collection,analysis and interpretation of data,in the writing of the manuscript,and in the decision to submit the manuscript for publication.
Human adenoviruses(HAdVs)can cause acute hepatitis in immunocompromised patients.However,it is unclear whether HAdVs are contributors to hepatitis in immunocompetent children.In this study,the liver function test(LFT)...
supported in part by the grant from National Natural Science Foundation of China(82171818,81703048,82041019,and 82101919);the grant from Defense Industrial Technology Development Program of China(JCKY2020802B001);Beijing Municipal Science and Technology Commission(Z201100005420024)。
Recombinant adenovirus serotype 5(Ad5)vector has been widely applied in vaccine development targeting infectious diseases,such as Ebola virus disease and coronavirus disease 2019(COVID-19).However,the high prevalence ...
Breast cancer,an unceasingly occurring neoplasm,is one of the major determinants of mortality in women.Several ineffective attempts have been pursued using with conventional therapies against breast cancer.Resistance ...
There has been an increasing number of reported cases of acute hepatitis of unknown origin in previously healthy children since first reported on March 31,2022.This clinical syndrome is identified by jaundice and mark...
funded by National Natural Science Foundation of China(81973402);Natural Science Foundation of Zhejiang Province(LYY22H310009);Hospital Pharmacy Scientific Research Funding Project of Zhejiang Pharmaceutical Association(2020ZYY10);Clinical research fund project of Zhejiang Medical Association(2020ZYC-A07).
Cerebral ischemia is a neurological disorder associated with complex pathological mechanisms,including autophagic degradation of neuronal mitochondria,or termed mitophagy,following ischemic events.Despite being well-d...