VACCINIA

作品数：30被引量：42H指数：3
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DNA vaccine prime and replicating vaccinia vaccine boost induce robust humoral and cellular immune responses against MERS-CoV in mice
《Virologica Sinica》2024年第3期490-500,共11页Xiuli Shen Shuhui Wang Yanling Hao Yuyu Fu Li Ren Dan Li Wenqi Tang Jing Li Ran Chen Meiling Zhu Shuo Wang Ying Liu Yiming Shao 
financially supported by National Nature Science Foundation of China(U20A20362);the Subject of SKLID(2020SKLID102).
As of December 2022,2603 laboratory-identified Middle East respiratory syndrome coronavirus(MERS-CoV)infections and 935 associated deaths,with a mortality rate of 36%,had been reported to the World Health Organization...
关键词：MERS-CoV VTT vaccine DNA vaccine Humoral and cellular immune responses Prime/boost strategy 
Vaccinia-related kinase 2 variants differentially affect breast cancer growth by regulating kinase activity
《Oncology Research》2024年第2期421-432,共12页SEUNG-HEE GWAK JUHYUN LEE EUNJI OH DOHYUN LEE WONSHIK HAN JONGMIN KIM KYONG-TAI KIM 
supported by the BK21 FOUR funded by the Ministry of Education,Republic of Korea,the National Research Foundation of Korea(NRF-2022R1F1A1066642,RS-2023-00272063)grant funded by the Korean government(MSIT),and POSTECH Basic Science Research Institute Grant(NRF-2021R1A6A1A10042944).Research was also supported by funds donated by Dr.Jae Kyu Lee and Mr.Jason Gim.Following are results of a study on the“Leaders in INdustry-University Cooperation 3.0”Project,supported by the Ministry of Education and National Research Foundation of Korea.
Genetic information is transcribed from genomic DNA to mRNA,which is then translated into threedimensional proteins.mRNAs can undergo various post-transcriptional modifications,including RNA editing that alters mRNA s...
关键词：VRK2 Kinase activity Breast cancer Tumor RNA editing Cell proliferation Cell growth 
Near obstructing painful anorectal mass and facial rash in a man with monkeypox: A case report
《World Journal of Clinical Cases》2023年第30期7418-7423,共6页Kesiena Akpoigbe Jones Yannick Joan Culpepper-Morgan 
BACKGROUND Monkeypox(MPX)is a zoonotic infection that is endemic in Western and Central Africa along the Congo River basin.It has a high case fatality rate especially in younger age groups.It belongs to the virus fami...
关键词：PROCTITIS MONKEYPOX Human Immunodeficiency Virus Men who have sex with Men Tecovirimat Vaccinia Immunoglobulin Case report 
Oncolytic viruses:A novel treatment strategy for breast cancer
《Genes & Diseases》2023年第2期430-446,共17页Mohammad Javanbakht Sanaz Tahmasebzadeh Luca Cegolon Nasrin Gholami Mandana Kashaki Hassan Nikoueinejad Mohamad Mozafari Mahsa Mozaffari Shi Zhao Mostafa Khafaei Morteza Izadi Saeid Fathi Reza Akhavan-Sigari 
Breast cancer,an unceasingly occurring neoplasm,is one of the major determinants of mortality in women.Several ineffective attempts have been pursued using with conventional therapies against breast cancer.Resistance ...
关键词：ADENOVIRUS Breast cancer Herpes virus Measles virus Newcastle disease virus REOVIRUS VACCINIA Vesicular stomatitis virus VIROTHERAPY 
A Deleted Deletion Site in a New Vector Strain and Exceptional Genomic Stability of Plaque-Purified Modified Vaccinia Ankara(MVA)
《Virologica Sinica》2020年第2期212-226,共15页Ingo Jordan Deborah Horn Kristin Thiele Lars Haag Katharina Fiddeke Volker Sandig 
Part of this work was financially supported by the EU FP7 Grant FLUNIVAC(Project-ID 602604).
Vectored vaccines based on highly attenuated modified vaccinia Ankara(MVA) are reported to be immunogenic, tolerant to pre-existing immunity, and able to accommodate and stably maintain very large transgenes. MVA is u...
关键词：Modified vaccinia Ankara(MVA) MVA-CR19 CR.pIX Suspension cell line Vaccine production Genome stability 
Improving Cross-Protection against Influenza Virus Using Recombinant Vaccinia Vaccine Expressing NP and M2 Ectodomain Tandem Repeats被引量：2
《Virologica Sinica》2019年第5期583-591,共9页Wenling Wang Baoying Huang Xiuping Wang Wenjie Tan Li Ruan 
supported by grant from the National Key Plan for Scientific Research and Development of China (2016YFC1200200)
Conventional influenza vaccines need to be designed and manufactured yearly.However,they occasionally provide poor protection owing to antigenic mismatch.Hence,there is an urgent need to develop universal vaccines aga...
关键词：Influenza A virus(IAV) CROSS-PROTECTION Recombinant vaccinia virus Conserved antigen 
Immune therapy for human papillomaviruses-related cancers被引量：12
《World Journal of Clinical Oncology》2014年第5期1002-1019,共18页Ricardo Rosales Carlos Rosales 
Supported by Dirección General de Asuntos del Personal Académico,Universidad Nacional Autónoma de México No.IN207514;Consejo Nacional de Ciencia y Tecnología,Mexico,No.168098
Human papillomaviruses(HPVs) are a large family of double strand DNA viruses comprising more than 180 types. Infection with HPV is very common and it is associated with benign and malignant proliferation of skin and s...
关键词：Human PAPILLOMAVIRUS T cell IMMUNOGLOBULIN ANTIBODY VACCINIA VIRUS 
Potent T cell Responses Induced by Single DNA Vaccine Boosted with Recombinant Vaccinia Vaccine被引量：1
《Virologica Sinica》2013年第2期109-115,共7页Lianxing Liu Chao Qiu Yang Huang Jianqing Xu Yiming Shao 
supported by the China Comprehensive Integrated Programs for Research on AIDS(CIPRA, U19AI51915);by the National Key Projects on Major Infectious Diseases (Grant No. 2008ZX10001-010,2012ZX10001-008);by the National Natural Science Foundation of China (31000413)
Plasmid DNA, an effective vaccine vector, can induce both cellular and humoral immune responses. However, plasmid DNA raises issues concerning potential genomic integration after injection. This issue should be consid...
关键词：HIV VACCINE T cell responses Prime-boost regimen 
A mouse model based on replication-competent Tiantan vaccinia expressing luciferase/HIV-1 Gag fusion protein for the evaluation of protective efficacy of HIV vaccine被引量：2
《Chinese Medical Journal》2009年第14期1655-1659,共5页HUANG Yang QIU Chao LIU Lian-xing FENG Yan-meng ZHU Ting XU Jian-qing 
This research was supported by the National Natural Science Foundation of China （No. 30771915）, the National Grand Program on Key Infectious Disease （No. 2008ZX10001-02 Project 2 and 2008ZX10001-012） from the China Ministry of Health ＆ Ministry of Sciences and Technology, China.
Background Developing an effective vaccine against human immunodeficiency virus type 1 （HIV-1） remains a grand challenge after more than two decades of intensive effort. It is partially due to the lack of suitable a...
关键词：human immunodeficiency virus type 1 vaccine mice model LUCIFERASE 
Brazilian vaccinia virus strains show a classical orthopoxvirus infection course and cross-protection
《Asian Pacific Journal of Tropical Medicine》2009年第2期21-26,共6页Jaqueline Maria Siqueira Ferreira Betnia Paiva Drumond J?natas Santos Abraho Zélia Inês Portela Lobato Cláudio Ant?nio Bonjardim Paulo César Peregrino Ferreira Erna Geessien Kroon 
Financial support was provided by CNPq, CAPES and FAPEMIG.Japueline M.S.Ferreira received fellowship from CAPES. R.M.S.Ferreira received fellowship from CAPES.R.M.E. P.C.P. Ferreira, C.A.Bonjardim,Z.I.P. Lobato and E.G.Kroon are recipients of research fellowship from CNPq
Objectives:The purpose of this work was to study the infection course and cross-protection in mice after intradermal injection of Vaccinia virus(VACV) strain Western Reserve and three Brazilian VACV strains: Aracatuba...
关键词：ORTHOPOXVIRUS ZOONOSES Balb/c mice INTRADERMAL injection VACCINIA virus Bovine VACCINIA outbreaks 
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