CROSS-PROTECTION

作品数：16被引量：15H指数：2
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相关期刊：《Signal Transduction and Targeted Therapy》《American Journal of Plant Sciences》《Stress Biology》《Journal of Integrative Agriculture》更多>>
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An asymptomatic geminivirus activates autophagy and enhances plant defenses against diverse pathogens
《Stress Biology》2024年第1期156-173,共18页Li Wang Zijie Yu Mengge Jiang Mengyuan Tian Hongsheng Zhou Wanying Zhao Ida Bagus Andika Qiaoxia Shang Liying Sun 
supported by the National Natural Science Foundation of China(31970163)to LS;Major Science and Technology Project of Beijing Municipal Education Commission(Grant no.KZ202210020028)to QS.
Plant viral diseases cause great losses in agricultural production.Virus cross-protection is a strategy in which a mild virus is employed to shield plants against subsequent infections by severe viral strains.However,...
关键词：Apple geminivirus AUTOPHAGY CROSS-PROTECTION PATHOGENS Resistance 
Strengthening global health resilience:Marburg virus-like particle vaccines and the One Health approach
《Science in One Health》2024年第1期35-41,共7页Ram Bahadur Khadka Khimdhoj Karki Jitendra Pandey Rabin Gyawali Gautam Prasad Chaudhary 
The Marburg virus(MARV),belonging to the Filoviridae family,poses a significant global health threat,emphasizing the urgency to develop Marburg virus-like particle(VLP)vaccines for outbreak mitigation.The virus's mena...
关键词：Marburg virus Virus-like particle vaccine CROSS-PROTECTION mRNA technology Global collaboration 
Development of a stable attenuated double-mutant of tobacco mosaic virus for cross-protection
《Journal of Integrative Agriculture》2024年第7期2318-2331,共14页Xiaojie Xu Shaoyan Jiang Chunju Liu Xujie Sun Qing Zhu Xiuzhai Chen Pengchao Jiang Fenglong Wang Yanping Tian Xiangdong Li 
supported by funds from‘Taishan Scholar’Construction Project,China(TS2022-028 and 202101KN275)。
Tobacco(Nicotiana tabacum)and tomato(Solanum lycopersicum)are two major economic crops in China.Tobacco mosaic virus(TMV;genus Tobamovirus)is the most prevalent virus infecting both crops.Currently,some widely cultiva...
关键词：CROSS-PROTECTION double-mutant p126 tobacco mosaic virus VIRULENCE 
Failure of Cronobacter sakazakii to acquire direct and cross-protection against lethal stresses after exposure to sublethal ethanol
《Food Quality and Safety》2024年第1期81-91,共11页Hongmei Niu Xiang Wang Yuan Wang Xiaojie Qin Yangtai Liu Zhuosi Li Xu Wang Wantong Zhang Qingli Dong 
the Shanghai Project of Food Safety Risk Assessment(RA-2022-10);the Shanghai Agriculture Applied Technology Development Program(2022-02-08-00-12-F01144),China.
Cronobacter sakazakii may encounter subinhibitory concentrations of ethanol stress over its lifecycle.Bacterial tolerance to homologous or heterologous stress agents may be altered as a result of ethanol adaptive resp...
关键词：Cronobacter sakazakii ethanol exposure stress tolerance direct resistance CROSS-RESISTANCE mechanisms. 
In search of a pan-coronavirus vaccine:next-generation vaccine design and immune mechanisms被引量：1
《Cellular & Molecular Immunology》2024年第2期103-118,共16页S.Cankat M.U.Demael L.Swadling 
funded by a Rosetrees Trust and Pears Foundation Advancement Fellowship,SC is funded by a BBSRC LIDo-DTP PhD studentship(BB/T008709/1);UD is funded by an MRC DTP PhD studentship(MR/W006774/1);funding from the UCL Therapeutic.Acceleration Support scheme supported by funding from MRC IAA 2021 UCL MR/X502984/1.
Members of the coronaviridae family are endemic to human populations and have caused several epidemics and pandemics in recent history.In this review,we will discuss the feasibility of and progress toward the ultimate...
关键词：VACCINE CORONAVIRUS Cross-reactive immunity CROSS-PROTECTION Universal 
Development and evaluation of neutralizing antibodies for cross-protection against West Nile virus and Japanese encephalitis virus
《Infectious Medicine》2023年第3期212-223,共12页Meng-Jie Yang Hao-Ran Luo Zhen-Yu Fan Yu-Xiang Feng Ning Wei Bi-Bo Zhu Jing Ye Sheng-Bo Cao You-Hui Si 
supported by the National Key R&D Program of China (2021YFD1801300);the Fundamental Research Funds for the Central Universities (2662023DKPY004);the Key Technological Innovation Program of Hubei Province (2019ABA089);Natural Science Foundation of Hubei Province (2019CFA010 and 2021CFA056).
Background:West Nile virus is a severe zoonotic pathogen that can cause severe central nervous system symptoms in humans and horses,and is fatal for birds,chickens and other poultry.With no specific drugs or vaccines ...
关键词：West Nile virus Neutralizing antibodies Cross protection Therapeutic antibodies HUMANIZATION 
Mouse model for pangolin-origin coronavirus GX/P2V/2017 infection and cross-protection from COVID-19 ZF2001 subunit vaccine
《hLife》2023年第1期35-43,共9页Xiao Qu Yunfei Jia Na Jia Huahao Fan Anqi Zheng Luoyuan Xia Zhenfei Wang Di Tian Sheng Niu Yu Hu Wenxia Tian Zhihai Chen Yigang Tong Yuwei Gao Wuchun Cao Qihui Wang George Fu Gao 
supported by the National Key R&D Program of China(2022YFC2303403 and 2021YFC0863400);the National Natural Science Foundation of China(NSFC 82225021 and 32000127);Q.W.is supported by the Youth Innovation Promotion Association CAS(Y2022037);G.F.G.is supported by the Yanqi Lake Meeting organized by the Academic Divisions of CAS.
Many severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)–related coronaviruses have been discovered,constituting potential threats to human health.However,it remains unclear whether the currently available va...
关键词：ZF2001 pangolin-origin coronavirus mouse model VACCINE protection 
Cross-neutralization and cross-protection among SARS-CoV-2 viruses bearing different variant spikes
《Signal Transduction and Targeted Therapy》2022年第9期3202-3205,共4页Yang Liu Jianying Liu Jing Zou Birte Kalveram Rafael R.G.Machado Ping Ren Sina Tureli Derek J.Smith Scott C.Weaver Xuping Xie Pei-Yong Shi 
Dear Editor The rapid evolution of SARS-CoV-2 mandates a better under-standing of cross-neutralization and cross-protection among variants.Such information is essential to guide vaccine strategy and public policy.To e...
关键词：vaccine CROSS BACKBONE 
A biepitope,adjuvant-free,self-assembled influenza nanovaccine provides cross-protection against H3N2 and H1N1 viruses in mice被引量：1
《Nano Research》2022年第9期8304-8314,共11页Yongbo Qiao YaXin Zhang Jie Chen Shenghui Jin Yarning Shan 
the National Natural Science Foundation of China(No.31770996).
Currently,the incorporation of multiple epitopes into vaccines is more desirable than the incorporation of a single antigen for universal influenza vaccine development.However,epitopes induce poor immune responses.Alt...
关键词：INFLUENZA universal vaccine MULTI-EPITOPE NANOVACCINE 
Sequential immunizations confer cross-protection against variants of SARS-CoV-2,including Omicron in Rhesus macaques被引量：5
《Signal Transduction and Targeted Therapy》2022年第5期1746-1755,共10页Wei Deng Qi Lv Fengdi Li Jiangning Liu Zhiqi Song Feifei Qi Qiang Wei Pin Yu Mingya Liu Shasha Zhou Yaqing Zhang Hong Gao Nan Wang Zijing Jia Kai Gao Jiayi Liu Chong Xiao Haiquan Shang Xiangxi Wang Linlin Bao Chuan Qin 
ACKNOWLEDGEMENTS We thank Sinovac Biotech Ltd for providing the inactivated vaccines as a gift for these prospective studies.This work was supported by the National Research and Development Project of China(Grant Nos.2021YFC0863300,2020YFA0707500,2018YFA0900801);the CAMS Initiative for Innovative Medicine of China(Grant No.2021-I2M-1-035);the Strategic Priority Research Program(XDB29010000,XDB37030000),CAS(YSBR-010);the Special Funds of the National Natural Science Foundation of China(Grant Nos.82061138007 and 92169210);Xiangxi Wang was supported by the Ten Thousand Talent Program and the NSFS Innovative Research Group(No.81921005).
Variants of concern(VOCs)like Delta and Omicron,harbor a high number of mutations,which aid these viruses in escaping a majority of known SARS-CoV-2 neutralizing antibodies(NAbs).In this study,Rhesus macaques immunize...
关键词：NEUTRAL HARBOR OMI 
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