国家自然科学基金(30472086)

作品数:2被引量:3H指数:1
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相关期刊:《Acta Pharmacologica Sinica》更多>>
相关主题:HIPPOCAMPUSACRTACROLIMUSHIPPOCAMPALMUS更多>>
相关领域:医药卫生生物学更多>>
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Electrophysiological characterization of a novel Kv channel blocker N, N'-[ oxy bis( 2,1-ethanediylo xy-2,1-ethanediyl) ] bis( 4-meth yl)-benzenesulfonamide found in virtual screening被引量:1
《Acta Pharmacologica Sinica》2008年第4期405-412,共8页Zhao-bing GAO Xue-qin CHEN Hua-liang JIANG Hong LIU Guo-yuan HU 
Project supported by research grants from the National Natural Science Foundation of China (№ 30472086 and 20472094) and a "863 Hi-Tech Program in China" grant (№ 2006AA020602).
Aim: N,N'- [oxybis(2,1 -ethanediyloxy-2,1 -ethanediyl)]bis(4-methyl)- benzenesulfonamide (OMBSA) is a hit compound with potent voltage-gated K^+ (Kv) channel-blocking activities that was found while searchi...
关键词:BLOCKER hippocampal neurons N N'-[oxybis (2  1-ethanediyloxy-2 1-ethanediyl)] bis(4- methyl)-benzenesulfonamide patch- clamping recording virtual screening voltagegated K^+ channel 
Electrophysiological actions of cyclosporin A and tacrolimus on rat hippocampal CA1 pyramidal neurons被引量:2
《Acta Pharmacologica Sinica》2007年第12期1891-1897,共7页Yong YU Xue-qin CHEN Yao-yuan CUI Guo-yuan HU 
Project partly supported by a grant from the National Natural Science Foundation of China(№ 30472086)
Aim: The aim of the present study was to investigate the electrophysiological actions of cyclosporin A (CsA) and tacrolimus (FK506) on neurons in the brain, and to elucidate the relevant mechanisms. Methods: Who...
关键词:action potential CALCINEURIN cyclosporin A delayed rectifier K+ channel HIPPOCAMPUS TACROLIMUS 
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