This project was supported by grants from the NationalNatural Sciences Foundation of China ( No . 39672065 ,39730270 ,and 39725027) ,the China State Key Basic Re-search Program ( No . G1998051212) , and the ScienceFoundation of Ministry of Health, P. R. China ( No .20012537) .
The threshold of cyclin E expression at G1/S boundary is a characteristic feature of cell cycle progressing. In this study, we tried to develop a quantitative approach to analyze cyclin E threshold by multiparameter f...