高等学校学科创新引智计划(111Project)

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The complexities of proanthocyanidin biosynthesis and its regulation in plants被引量：3
《Plant Communications》2023年第2期12-27,共16页Keji Yu Yushuang Song Jinxing Lin Richard A.Dixon 
supported by the Program of Introducing Talents of Discipline to Universities(111 Project,B13007);the National Natural Science Foundation of China(32030010);the China Postdoctoral Science Foundation(2020M680404 to K.Y.).
Proanthocyanidins(PAs)are natural flavan-3-ol polymers that contribute protection to plants under biotic and abiotic stress,benefits to human health,and bitterness and astringency to food products.They are also potent...
关键词：condensed tannin proanthocyanidin carbocation chemistry metabolic channeling non-enzymatic polymerization 
Cartilage-targeting and inflammatory-responsive nanocarriers for effective osteoarthritis treatment via reactive oxygen species scavenging and anti-angiogenesis
《Journal of Materials Science & Technology》2023年第12期30-42,共13页Sixiang Wang Yan Gao Lili Dong Peixing Chen Wanqian Liu Li Yang 
financially supported by the National Natural Science Foundation of China (Nos.11532004 and 11832008);the Innovation and Attracting Talents Program for College and Univer-sity (“111”Project) (No.B06023).
Osteoarthritis(OA),a common disabling joint disease,is highly associated with microenvironmental changes in the cartilage and subchondral bone.Elevated reactive oxygen species(ROS)in the cartilage and subchondral bone...
关键词：OSTEOARTHRITIS Reactive oxygen species Angiogenesis Cartilage-targeting Drug delivery systems Chitosan-catechol nanocarriers 
NETO2 promotes melanoma progression via activation of the Ca^(2+)/CaMKⅡ signaling pathway
《Frontiers of Medicine》2023年第2期263-274,共12页Susi Zhu Xu Zhang Yeye Guo Ling Tang Zhe Zhou Xiang Chen Cong Peng 
supported by the National Natural Science Foundation of China(Nos.82073458,82173424,81773341,81772917,and 81830096);supported by the Science and Technology Innovation Program of Hunan Province(No.2021RC4013);the Program of Introducing Talents of Discipline to Universities(111 Project,No.B20017)。
Melanoma is the most aggressive cutaneous tumor.Neuropilin and tolloid-like 2(NETO2)is closely related to tumorigenesis.However,the functional significance of NETO2 in melanoma progression remains unclear.Herein,we fo...
关键词：MELANOMA neuropilin and tolloid-like 2 CA^(2+) CaMKII signaling pathway 
大洋地幔地震波低速带(LVZ)起源于由水导致的微量初始熔体被引量：1
《Science Bulletin》2023年第4期359-363,M0003,共6页牛耀龄 
supported by the National Natural Science Foundation of China(91958215);the Ministry of Education Overseas Expertise Introduction Project for Discipline Innovation(111 Project,B18048)。
It is reasonable to state that if there were no seismic low velocity zone(LVZ)beneath ocean basins,there would be no seafloor spreading and plate tectonics.Over the past 50 years,plate tectonics has been developed int...
关键词：低速带 MANTLE 初始熔体 
A novel procedure for identifying a hybrid QTL-allele system for hybrid-vigor improvement, with a case study in soybean(Glycine max)yield
《The Crop Journal》2023年第1期177-188,共12页Jinshe Wang Jianbo He Jiayin Yang Junyi Gai 
supported by the National Key Research and Development Program of China (2021YFF1001204,2017YFD0101500);the MOE Program of Introducing Talents of Discipline to Universities (“111”Project, B08025);the MOE Program for Changjiang Scholars and Innovative Research Team in University (PCSIRT_17R55);the MARA CARS-04 Program;the Jiangsu Higher Education PAPD Program;the Fundamental Research Funds for the Central Universities (KYZZ201901);the Jiangsu JCICMCP Program。
“Breeding by design” for pure lines may be achieved by construction of an additive QTL-allele matrix in a germplasm panel or breeding population, but this option is not available for hybrids, where both additive and...
关键词：Breeding by design Diallel hybrid population PLSRGA(partial least squares regression via genetic algorithm) QTL-allele matrix of additive/dominance effect Simulation experiment Soybean[Glycine max(L.)Merr.] 
Identification of Epsin1 as a regulator for hepatic lipid and glucose metabolism
《Genes & Diseases》2023年第1期72-75,共4页Xiaohua Huang Long Jin Zhengfeng Fang Lianqiang Che Yan Lin Shengyu Xu Yong Zhuo Mingzhou Li De Wu Bin Feng 
This study was supported by the National Natural Science Foundation of China(No.31900834);the China's Overseas Expertise Introduction Project for Discipline Innovation("111 Project")(No.D17015).
Obesity related non-alcoholic fatty liver disease(NAFLD),which can progress to steatohepatitis and insulin resistance,has become a major chronic liver disease worldwide.1 As an adaptor of clathrin-mediated endocytosis...
关键词：METABOLISM HEALING WOUND 
Determination of multiaxial stress rupture criteria for creeping materials:A critical analysis of different approaches
《Journal of Materials Science & Technology》2023年第6期14-25,共12页Kun Zhang Jian-Ping Tan Wei Sun Kamran Nikbin Shan-Tung Tu 
This work was financially supported by Projects of the National Natural Science Foundation of China(Nos.521130511,11502082,52075174);the Higher Education Discipline Innovation Project("111 Project")(No.B13020).Helpful discussions with Jian-Feng Wen and Guo-Zhen Wang at the East China University of Science and Technology and Qiang Xu at the University of Huddersfield are gratefully acknowledged.
Materials in engineering applications are rarely uniaxially-loaded.In reality,failures under multiaxial loading has been widely observed in engineering structures.The life prediction of a component under multiaxial st...
关键词：Multiaxial stress rupture criterion Creep failure mechanism Uniaxial parameter Creep damage tolerance parameter Continuum damage mechanics 
Evaluating the pharmacokinetics of intrapulmonary administered ciprofloxacin solution for respiratory infections using in vivo and in silico PBPK rat model studies
《Chinese Chemical Letters》2023年第1期230-234,共5页Changzhi Shi Jelisaveta Ignjatovic Junwei Wang Yi Guo Li Zhang Sandra Cvijic Dongmei Cun Mingshi Yang 
financially supported by the Liaoning Pan Deng Xue Zhe Scholar(No.XLYC2002061);the National Natural Science Foundation of China(No.81573380);the Overseas Expertise Introduction Project for Discipline Innovation(“111 Project”)(No.D20029);financial support from the Guiding Project for Science and Technology of Liaoning Province(No.2019-ZD-0448);Ministry of Education Chunhui Program(2020);support from Ministry of Education Science and Technological Development,Republic of Serbia(No.451-03-9/2021-14/200161)。
Respiratory antibiotics have been proven clinically beneficial for the treatment of severe lung infections such as Pseudomonas aeruginosa.Maintaining a high local concentration of inhaled antibiotics for an extended t...
关键词：Inhalation antibiotics CIPROFLOXACIN Controlled release PBPK modeling Lung infections 
Space-frequency-polarization-division multiplexed wireless communication system using anisotropic space-time-coding digital metasurface被引量：3
《National Science Review》2022年第11期144-155,共12页Jun Chen Ke Xiangyu Chen Wankai Tang Ming Zheng Chen Lei Zhang Li Wang Jun Yan Dai Jin Yang Jun Wei Zhang Lijie Wu Qiang Cheng Shi Jin Tie Jun Cui 
supported by the Basic Scientific Center of Information Metamaterials of the National Natural Science Foundation of China (62288101);the National Key Research and Development Program of China (2017YFA0700201,2017YFA0700202, 2017YFA0700203 and 2018YFA0701904);the National Natural Science Foundation of China (61731010);the Overseas Expertise Introduction Project for Discipline Innovation (111 Project)(111-2-05);the Jiangsu Province Frontier Leading Technology Basic Research Project (BK20212002);Fundamental Research Funds for the Central Universities(2242022k30004);the China Postdoctoral Science Foundation(2020M680062);the National Postdoctoral Program for Innovative Talents (BX2021062);the National Science Foundation of China for Distinguished Young Scholars (61625106)
In the past few years,wireless communications based on digital coding metasurfaces have gained research interest owing to their simplified architectures and low cost.However,in most of the metasurface-based wireless s...
关键词：polarization-division multiplexing frequency-division multiplexing space-division multiplexing space-time coding wireless communication 
Circular RNA circCCNB1 inhibits the migration and invasion of nasopharyngeal carcinoma through binding and stabilizing TJP1 mRNA被引量：5
《Science China(Life Sciences)》2022年第11期2233-2247,共15页Mengyao Zhao Yian Wang Fenghua Tan Lingyun Liu Xiangchan Hou Chunmei Fan Le Tang Yongzhen Mo Yumin Wang Qijia Yan Zhaojian Gong Zheng Li Qianjin Liao Can Guo He Huang Xi Zeng Guiyuan Li Zhaoyang Zeng Wei Xiong Fuyan Wang 
the National Natural Science Foundation of China(82002239,82072374 and 82073135);the Overseas Expertise Introduction Project for Discipline Innovation(111 Project,111-2-12);the Natural Science Foundation of Hunan Province(2021JJ41043 and 2021JJ30897);Central South University Graduate Research and Innovation Project(2021zzts0310)。
Nasopharyngeal carcinoma(NPC)is a malignant tumor that usually occurs in people from Southeast Asia and Southern China.NPC is prone to migration and invasion,leading to poor prognosis.A large number of circular RNAs(c...
关键词：nasopharyngeal carcinoma circCCNB1 NF90 TJP1 migration and invasion 
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