This project was supported by the National Natural Science Foundation of China ( No. 30100087, 30500148, 30571770);funded by the Collaborating Research Fund for Young Scholars from Abroad of National Natural Science Foundation of China ( No. 30228018 ).
Objective To identify the genetype of the PS1/APP double transgenie mouse model, then to analyse the histopathological changes in the brain and compare the differences between the transgenie mice models and Aβ1-40-in...