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国家自然科学基金(21175020): 作品数：12被引量：22H指数：3; 导出分析报告; 相关作者：王雪梅姜晖吴德洪燕红吴春惠更多>>; 相关机构：东南大学电子科技大学南京大学更多>>; 相关期刊：《Science China Chemistry》《药学学报》《物理化学学报》《光谱学与光谱分析》更多>>; 相关主题：NANOCOMPOSITESFERROCENECARBORANE相互作用微环境更多>>; 相关领域：理学化学工程医药卫生生物学更多>>

多策略可控合成原子精度合金纳米团簇（英文）: 《物理化学学报》2018年第7期740-754,共15页郑有坤姜晖王雪梅; supported by the National High Technology Research and Development Program of China(2015AA020502);the National Key Research and Development Program of China(2017YFA0205300);the National Natural Science Foundation of China(81325011,21175020)~~; 合金纳米团簇作为一类新兴的多功能纳米材料已被广泛用于催化、光学传感以及生物医学成像等研究领域,而纳米团簇的可控合成和结构特征是调节纳米团簇性质并对其进一步利用的基础。尽管当前有关金属纳米团簇可控合成和结构特征的研究主...; 关键词：合金纳米团簇原子精度合成策略晶体结构

Highly sensitive electrochemical detection of living cells based on diamond microelectrode arrays: 《Chinese Chemical Letters》2018年第6期919-921,共3页Jun Ruan Wenbo Zhang Hang Zhang Yun Chen Fawad Ur Rehman Hui Jiang Steffen Strehle Alberto Pasquarelli Xuemei Wang; financially supported by the National High Technology Research and Development Program of China (No. 2015AA020502);the National Natural Science Foundation of China (Nos. 81325011, 21175020, 21327902);the Fundamental Research Funds for the Central Universities of China (No. 2242016K41023);the Project "Strategic Partnerships U5" of Ulm University, Ulm, Germany;funded by the German Academic Exchange Service (DAAD);the German Ministry for Education and Research (BMBF); We designed boron-doped nanocrystalline diamond microelectrode arrays（BNCD-MEAs） with 16 channels for the bioanalysis of multicellular samples, which could be readily adapted for a highly sensitive detection of H2 O...; 关键词：BNCD-MEAs 16 Channels BIOANALYSIS Stimulated cells H2O2 detection

Green photochemical synthesis of fluorescent carbon spheres in-situ enwrapped around Ag nanoparticles: 《Science China Chemistry》2015年第4期634-639,共6页Wei Ge Xiaoli Liu Jing Ye Qiwei Li Hui Jiang Xuemei Wang; supported by the National Basic Research Program of China(2010CB732404);the National Natural Science Foundation of China(81325011,21327902,21175020);the National High Technology Research and Development Program of China(2012AA022703);the Suzhou Science&Technology Major Project(ZXY2012028); Biocompatible carbon-spheres-based nanocomposites exhibit great potential in biomedical and clinical applications. In this contribution we report the first green photochemical synthesis of carbon spheres through in-si...; 关键词：carbon spheres silver nanoparticles CS-Ag NPs nanocomposites antibacterial activity

In-situ green synthesis of highly active GSH-capped Pt–Au–Ag-hybrid nanoclusters被引量：2: 《Science China Chemistry》2014年第11期1532-1537,共6页CHEN DongHua GAO ShengPing UR REHMAN Fawad JIANG Hui WANG XueMei; supported by the National Basic Research Program of China(2010CB732404);the National Natural Science Foundation of China(81325011,21327902,21175020);the National High Technology Research and Development Program of China(2012AA022703);the Major Science&Technology Project of Suzhou(ZXY2012028); Recently much attention has been paid to the application of metal hybrid nanoparticles in industrial catalytic fields because of their super-efficient catalytic activity and attractive properties. We explored a novel ...; 关键词：Pt–Au–Ag-hybrid ascorbic acid glutathione 4-NITROPHENOL catalyst

Enhanced in vitro anticancer activity of quercetin mediated by functionalized CdTe QDs被引量：2: 《Science China Chemistry》2014年第11期1579-1588,共10页WU ChunHui SHI LiXin WU ChangYu GUO DaDong SELKE Matthias WANG XueMei; supported by the National Basic Research Program of China(2010CB732404);the National Natural Science Foundation of China(21175020);the Project of the Ministry of the Science & Technology of China(2007AA022007);the Natural Science Foundation of Jiangsu Province(BK2008149);the support of National Natural Science Foundation of China(81101147);the China Postdoctoral Science Foundation(2011M501297);the China Postdoctoral Science Special Foundation(2012T50773);the Fundamental Research Funds for the Central Universities(ZYGX2011J099);the support by the State Key Laboratory of Bioelectronics,Southeast University,Nanjing 210096,China(2011E09);the Research Start-up Grants for New Science Faculty of University of Electronic Science and Technology of China(Y02002010901035);support from the United States NSF-CREST program(HRD0932421); We report in this study the effects of red-emitting CdTe QDs capped with cysteamine(Cys-CdTe) on the in vitro anticancer activity of the well-known flavenoid quercetin(Qu). Various techniques, including the methylthia...; 关键词：quantum dots QUERCETIN NANOCOMPOSITES cancer cell inhibition

The cellular labeling and pH-sensitive responsive-drug release of celastrol in cancer cells based on Cys-CdTe QDs被引量：6: 《Science China Chemistry》2014年第6期833-841,共9页LI JingYuan SHI LiXin SHAO YiXiang SELKE Matthias CHEN BaoAn JIANG Hui WANG XueMei; supported by the National Science Foundation for Distinguished Young Scholars of China (81325011);the National Basic Research Program of China (2010CB732404);the National Natural Science Foundation of China (21175020);the Natural Science Foundation of Jiangsu Province University (13KJB310015);the Open Research Fund of the State Key Laboratory of Bioelectronics,Southeast University;the Science and Technology Foundation of Nantong City (BK2013045);the Startup Foundation for Introduced Talents at Nantong University;support by the United States NSF-CREST program (HRD0932421); As one of the active compounds derived from Traditional Chinese Medicine,Celastrol(CSL)had cytotoxicity for human leukemia cancer cells K562 and its multidrug-resistant cell line K562/A02.Here,we introduced cysteamine...; 关键词：CELASTROL cysteamine-modified CdTe QDs leukemia cancer cells LABELING drug delivery

Glucose biosensor based on new carbon nanotube–gold–titania nano-composites modifed glassy carbon electrode被引量：2: 《Chinese Chemical Letters》2013年第12期1087-1090,共4页Yue-Li Wu Qi-Wei Li Xiao-Lu Zhang Xiao Chen Xue-Mei Wang; support from National Key Basic Research Program (No. 2010CB732404);National Natural Science Foundation of China (No. 21175020);Qinglan Project Sci-Tech Innovation Team of Jiangsu Province;Suzhou Science & Technology Major Project (No. ZXY2012028); In this paper, a novel biosensor was prepared by immobilizing glucose oxidase （GOx） on carbon nanotube-gold-titania nanocomposites （CNT/Au/TiO2） modified glassy carbon electrode （GCE）. SEM was initially used to ...; 关键词：Biosensor Glucose oxidase CNT/Au/TiO2

New strategy for reversing biofilm-associated antibiotic resistance through ferrocene-substituted carborane ruthenium(Ⅱ)-arene complex: 《Science China Chemistry》2013年第5期595-603,共9页LI ShuiHong WU ChangYu TANG Xiao GAO ShengPing ZHAO XinQing YAN Hong WANG XueMei; the financial support from National Nature Science Foundation of China (21175020);National Key Basic Research Program (2010CB732404);Graduate Research and Innovation Program of Jiangsu Province (CXLX_0145); Bacterial biofilms are inherently resistant to antimicrobial agents and are difficult to eradicate with conventional antimicrobial agents, resulting in many persistent and chronic bacterial infections. In this contrib...; 关键词：bacterial biofilms carborane ruthenium(Ⅱ)-arene complex antibiotic resistance

Discovery of ferrocene-carborane derivatives as novel chemical antimicrobial agents against multidrug-resistant bacteria被引量：2: 《Science China Chemistry》2012年第11期2388-2395,共8页LI ShuiHong WU ChangYu LV XiaYi TANG Xiao ZHAO XinQing YAN Hong JIANG Hui WANG XueMei; supported by the National Natural Science Foundation of China (21175020);National Key Basic Research Program (2010CB732404);Doctoral Fund of Ministry of Education of China (20090092110028);National High Technology Research and Development Program(2007AA022007);Guangdong Province (2011B090400357);Graduate Research and Innovation Program of Jiangsu Province (CXLX_0145);State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences; Antimicrobial resistance has now become a very serious global public health problem. New drug discovery and development are urgently needed to combat the growing threat of multidrug-resistant (MDR) bacteria. The aim o...; 关键词：multidrug-resistant bacteria ferrocene-carborane derivatives bactericidal effect BIOCOMPATIBILITY minimal inhibitoryconcentration

Study on specific interaction of new ferrocene-substituted carborane conjugates with hemoglobin protein被引量：1: 《Science China Chemistry》2012年第4期594-603,共10页WU ChunHui1,3, YE HongDe2, JIANG Hui1, WANG XueMei1 & YAN Hong2 1State Key Lab of Bioelectronics (Chien-Shiung Wu Lab), Southeast University, Nanjing 210096, China 2State Key Laboratory of Coordination Chemistry School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China 3School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China; supported by the National Basic Research Program of China (2010CB732404, 2010CB923303);the National Natural Science Foundation of China (21175020, 90713023, 20925104);the Project of High Technology Research and Development Program of China (2007AA022007);Gongdong Province (2011B090400357);the Natural Science Foundation of Jiangsu Province (BK2008149, BK2010052);C. W. acknowledges the Fundamental Research Funds for the Central Universities (ZYGX2011J099);the support by the Open Research Fund of State Key Laboratory of Bioelectronics, Southeast University (2011E09); The interactions between the new organometallic complexes, ferrocenesubstituted dithioocarborane conjugates （denoted as FcSB1, FcSB2 and FcSBCO） and hemoglobin （Hb） are investigated by electrochemistry, fluorescen...; 关键词：fluorescence – UV vis absorption spectroscopy – differential pulse voltammetry – biomolecular interaction – ferrocene substituted carborane conjugates – hemoglobin

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