国家自然科学基金(30873053)

作品数：2被引量：12H指数：2
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相关期刊：《Neuroscience Bulletin》更多>>
相关主题：DEFICIENCYASTROCYTELESIONSINFLAMMATIONAQP4更多>>
相关领域：生物学医药卫生自动化与计算机技术更多>>
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Aggravated inflammation and increased expression of cysteinyl leuko-triene receptors in the brain after focal cerebral ischemia in AQP4-deficient mice被引量：6
《Neuroscience Bulletin》2012年第6期680-692,共13页Wen-Zhen Shi Chun-Zhen Zhao Bing Zhao Qiao-Juan Shi Li-Hui Zhang Yan-Fang Wang San-Hua Fang Yun-Bi Lu Wei-Ping Zhang Er-Qing Wei 
supported by the National Natural Science Foundation of China(81273491, 81072618,30772561 and 30873053);the Natural Science Foundation of Zhejiang Province,China(Y2090069);the"Qianjiang Rencai Research Plan"of Zhejiang Province China(2010R10055);the Fundamental Research Funds for the Central Universities,China(2009QNA7008)
Objective Aquaporin-4 （AQP4）, the main water channel protein in the brain, plays a critical role in water homeostasis and brain edema. Here, we investigated its role in the inflammatory responses after focal cerebra...
关键词：aquaporin 4 gene deficiency INFLAMMATION cysteinyl leukotriene receptor MICROGLIA ASTROCYTE focal cerebral ischemia 
Aquaporin-4 deficiency attenuates acute lesions but aggravates delayed lesions and microgliosis after cryoinjury to mouse brain被引量：6
《Neuroscience Bulletin》2012年第1期61-68,共8页Wen-Zhen Shi Chun-Zhen Zhao Bing Zhao Xiao-Liang Zheng San-Hua Fang Yun-Bi Lu Wei-Ping Zhang Zhong Chen Er-Qing Wei 
supported by the National Natural Science Foundation of China (81072618,30772561,30873053 and 30672449);the Natural Science Foundation of Zhejiang Province,China (Y2090069);the "Qian Jiang Ren Cai Research Plan" Zhejiang Province,China (2010R10055);Fundamental Research Funds for the Central Universities of China (2009QNA7008)
Objective To determine whether aquaporin-4 （AQP4） regulates acute lesions, delayed lesions, and the associated microglial activation after cryoinjury to the brain. Methods Brain cryoinjury was applied to AQP4 knocko...
关键词：AQUAPORIN-4 gene deficiency CRYOINJURY microglia ASTROCYTE 
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