National Natural Science Foundation of China (Grant No.30873170)
In the present study, we prepared novel NGR-modified PEG-PLGA polymeric micelles containing paclitaxel (NGR- PM-PTX) in order to evaluate their potential targeting to aminopeptidase N receptors expressed on tumor en...
National Natural Science Foundation of China (Grant No.30873170);the National Basic Research Program of China(973 Program 2007CB935800 and 2009CB930300)
Mitochondria are increasingly recognized as important targets for tumor treatment because of their central roles in apoptotic pathways and cellular metabolism. Dichloroacetate (DCA), a low molecular weight mitochond...
National Natural Science Foundation of China (Grant No. 30873170)
Endothelial cells in the angiogenic vessels of solid tumors over-express several proteins, which could be recognized by some peptide ligands. In this study, the targeting properties of two peptides, RGD (arginine-gly...