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国家自然科学基金(30371638): 作品数：16被引量：33H指数：4; 导出分析报告; 相关作者：陈忠徐莉莎胡薇薇谷内一彦李青更多>>; 相关机构：浙江大学杭州医学院日本东北大学金华市中心医院更多>>; 相关期刊：《Acta Pharmacologica Sinica》《中国药理通讯》《浙江大学学报（医学版）》更多>>; 相关主题：RATS脑内癫痫戊四唑KINDLING更多>>; 相关领域：医药卫生更多>>

急性最大电休克和慢性经耳电点燃癫痫对大鼠学习和记忆的影响被引量：6: 《浙江大学学报（医学版）》2007年第2期134-140,共7页李青吴登唱张琦陈忠; 国家自然科学基金资助项目(30371638);浙江省青年人才基金项目(R303779);浙江医学高等专科学校自然科学基金项目(2005XZ03); 目的:探讨急性最大电休克和慢性经耳电点燃癫痫对大鼠学习和记忆的影响。方法:通过双耳夹给予大鼠电刺激(150mA,0.2s)诱发急性最大电休克(MES),而慢性经耳电点燃癫痫,是经双耳夹每24h给予大鼠一次亚惊厥剂量电刺激(40mA,0.2s)直至完全...; 关键词：癫痫/病理生理学记忆障碍/病因学参考记忆工作记忆动物实验

Endogenous histamine inhibits the development of morphine-induced conditioned place preference被引量：2: 《Acta Pharmacologica Sinica》2007年第1期10-18,共9页Ying-xia GONG Min LV Yong-ping ZHU Yuan-yuan ZHU Er-qing WEI Hong SHI Qun-li ZENG Zhong CHEN; a National Rasic Research of China grant (No_ 2003CB515400);National Natural Science Foundation of China grants(No_ 30371638, 30472013 and 30572176);the Zhejiang Provincial Natural Science Foundation of China (No 8303779); Aim： The conditioned place preference （CPP） paradigm was used to investigate the effects of endogenous histamine on the processes leading to morphineinduced reward-seeking behavior in Sprague-Dawley rats. Methods：...; 关键词：conditioned place preference HISTAMINE MORPHINE RAT tuberomammillary nucleus

Carnosine inhibits pentylenetetrazol- induced seizures by histaminergic mechanisms in histidine decarboxylase knock- out mice: 《中国药理通讯》2006年第4期57-57,共1页Zhu Yuan - Yuan Zhu - Ge Zheng-Bing Wu Deng - Chang Wang Shuang Chen Zhong; This Project was supported by grants from the National Natural Science Foundation of China （30371638, 30600194, 30572176 ）, and the Zhejiang Provincial Natural Science Foundation of China （ R303779 ）; 关键词：组胺脱羧酶敲除小鼠戊四唑诱发癫痫肌肽抑制作用代谢通路

Unilateral low -frequency stimulation of central piriform cortex has inhibitory effect on amygdaloid- kindled seizures in rats: 《中国药理通讯》2006年第4期54-55,共2页Zhu - Ge Zheng - Bing Zhu Yuan - Yuan Wu Deng - Chang Wang Shuang Chen Zhong; This Project was supported by grants from the National Natural Science Foundation of China （30371638, 30572176, 30600194）, and the Zhejiang Provincial Natural Science Foundation of China （R303779）; 关键词：大鼠梨状皮质单侧低频刺激杏仁核点燃癫痫四肢抽搐抑制作用

Low frequency stimulation of fastigial nucleus delays amygdaloid kindling seizures in rats: 《中国药理通讯》2006年第4期55-55,共1页Wang Shuang Wu Deng - Chang Zhu - Ge Zheng - Bing Zhu Yuan- Yuan Chen Zhong; This Project was supported by grants from the National Natural Science Foundation of China （30600194, 30371638, 30572176）; 关键词：大鼠顶核低频刺激杏仁核点燃癫痫耐药性癫痫

ω- Conotoxin MVIIA inhibits amygdaloid kindled seizures in rats: 《中国药理通讯》2006年第4期55-56,共2页Wu Deng-Chang Wang Shuang Zhu Yuan-Yuan Chen Zhong; This Project was supported by grants from the National Natural Science Foundation of China （30371638, 30572176, 30600194）; 关键词：大鼠杏仁核点燃癫痫 ω -芋螺毒素MVIIA 抑制作用

Lesion of the TM E2 -region attenuates postictal seizure protection in rats: 《中国药理通讯》2006年第4期56-56,共1页Wu Deng - Chang Zhu - Ge Zheng - Bing Wang Shuang Zhu Yuan - Yuan Jin Chun -Lei Chen Zhong; This Project was supported by grants from the National Natural Science Foundation of China （30371638, 30572176, 30600194） , and the Zhejiang Provincial Natural Science Foundation of China （R303779）; 关键词：大鼠癫痫发作后保护下丘脑结节乳头核E2区电解损毁

Low - frequency stimulation of histaminergic tuberomammillary nucleus facilitates basolateral amygdaloid kindling in rats: 《中国药理通讯》2006年第4期56-57,共2页Zhu- Ge Zheng-Bing Wu Deng- Chang Wang Shuang Jin Chun- Lei Chen Zhong; 　 This Project was supported by grants from the National Natural Science Foundation of China （30371638, 30572176, 30600194）, and the Zhejiang Provincial Natural Science Foundation of China （ R303779 ）　; 关键词：大鼠基底外侧杏仁核点燃癫痫低频刺激下丘脑结节乳头核组胺能神经元

慢性经耳电点燃癫痫对大鼠穿梭箱被动回避反应的记忆保持能力的作用被引量：5: 《浙江大学学报（医学版）》2006年第4期419-423,共5页李青刘路英朱媛媛周文霞陈忠; 国家自然科学基金资助项目(30371638);浙江省青年人才基金项目(R303779);浙江医学高等专科学校自然科学基金项目(2005XZ03); 目的：探讨慢性经耳电点燃癫痫对大鼠穿梭箱被动回避反应的记忆保持能力的影响。方法：大鼠每24h一次经双耳夹给予亚惊厥剂量电刺激（40mA，0．2S）诱发电点燃大发作癫痫，然后利用穿梭箱系统检测大鼠的被动回避反应的记忆保持能力，HE...; 关键词：癫痫/并发症记忆障碍/病因学穿梭箱疾病模型动物

Histamine ameliorates spatial memory deficits induced by MK-801 infusion into ventral hippocampus as evaluated by radial maze task in rats被引量：1: 《Acta Pharmacologica Sinica》2005年第12期1448-1453,共6页Li-sha XU Li-xia YANG Wei-wei HU Xiao YU Li MA Lu-ying LIU Er-qing WEI Zhong CHEN; Project supported by the National Natural Science Foundation of China(No 30000019,30371638,30472013);the Zhejiang Provincial Natural Science Foundation of China(No R303779).; Aim：To investigate the role of histamine in memory deficits induced by MK-801 infusion into the ventral hippocampus in rats. Methods： An 8-arm radial maze （4 arms baited） was used to assess spatial memory. Results...; 关键词：HISTAMINE maze： learning MK-801 working memory： reference memory ventral hippocampus histamine H1 receptor

国家自然科学基金(30371638)