《Virologica Sinica》

作品数：1582被引量：3857H指数：21
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《Virologica Sinica》
主办单位：中国科学院武汉病毒研究所;中国微生物学会
最新期次：2025年1期更多>>
发文主题：VIRUSSARS-COVINFECTIONVIRALVACCINE更多>>
发文领域：医药卫生农业科学生物学文化科学更多>>
发文作者：庞义袁志明余健秀张用梅陈新文更多>>
发文机构：中国科学院中山大学华中农业大学中国农业科学院生物防治研究所更多>>
发文基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金广东省自然科学基金更多>>
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Insights into recent advancements in human and animal rotavirus vaccines:Exploring new frontiers
《Virologica Sinica》2025年第1期1-14,共14页Ahmed H.Ghonaim Sherin R.Rouby Wedad M.Nageeb Ashraf Ahmed Elgendy Rong Xu Changsheng Jiang Noha H.Ghonaim Qigai He Wentao Li 
supported by the National Key Laboratory of Agricultural Microbiology(AML2023A02);the Fundamental Research Funds for the Central Universities(2662023DKPY004).
Rotavirus infections cause severe gastroenteritis and dehydration in young children and animals worldwide,leading to high rates of morbidity and mortality,predominantly in low-and middleincome countries.In the past de...
关键词：Group A rotavirus Childhood diarrhea Domestic animals Rotavirus vaccines One health 
Gene flow and its sporadic spillover:H10 and N5 avian influenza viruses from wild birds and the H10N5 human cases in China
《Virologica Sinica》2025年第1期15-23,共9页Weijie Chen Shuiping Lu Haiyan Xiong Zhiyu Xiang Yuxi Wang Jingjing Hu Yue Pan Yanjiao Li Qile Gao Qi Chen Siru Hu Weibing Wang Chenglong Xiong 
funded by the National Natural Science Foundation of China(81872673);the Shanghai New Three-year Action Plan for Public Health(GWVI-11.1-03).
On January 30,2024,China announced the first human case of H10N5 influenza infection.Prior to this,human cases of H10N7 and H10N8 had been reported.It is now appropriate to re-examine the evolution and future epidemio...
关键词：Avian influenza virus(AIV) H10N5 REASSORTMENT Evolution Migration flyway 
Alowpathogenic avian influenzaA/Mallard/South Korea/KNU2019-34/2019(H1N1)virus has the potential to increase the mammalian pathogenicity
《Virologica Sinica》2025年第1期24-34,共11页Jaemoo Kim Jungho Kim Suhyeon Heo Chang-Hun Yeom Bao Tuan Duong Haan Woo Sung Seon-Ju Yeo Hyun Park Haryoung Poo Jihyun Yang 
funded by grants from the National Research Foundation of Korea(NRF)grant funded by the Korea government(2018M3A9H4055203 and 2023R1A2C2003679);from the Korea Health Technology R&D Project through the Korea Health Industry Development Institute(KHIDI),funded by the Ministry of Health&Welfare,Republic of Korea(HV23C1857);from KRIBB Research Initiative Program(KGM9942421).
Influenza,a highly contagious respiratory infectious disease caused by an influenza virus,is a threat to public health worldwide.Avian influenza viruses(AIVs)have the potential to cause the next pandemic by crossing t...
关键词：Avian influenza virus(AIV) H1N1 Zoonotic potential Mutation Receptor binding specificity FERRET 
PB2627V and HA 217 sites synergistically affect the lethality of H9N2 in mice
《Virologica Sinica》2025年第1期35-49,共15页Lingcai Zhao Miao Tian Xifeng Hu Menglu Fan Chenglin Hou Jihui Ping 
supported by National Natural Science Foundation of China[Grant number:32272992(JP),31772775(JP)];National Key Research and Development Program of China[Grant number:2021YFD1800205(JP)].
The H9N2 subtype avian influenza virus(AIV)continues to propagate and undergo evolution within China,thereby posing a significant threat to the poultry industry.This study encompassed the collection of 436 samples and...
关键词：Avian influenza virus(AIV) H9N2 PB2627V HA 217M PATHOGENICITY 
Comparative analysis between genotypes of adenovirus isolates from hospitalized children with acute respiratory tract infections and clinical manifestations in Wuhan,China,from June 2022 to September 2023
《Virologica Sinica》2025年第1期50-60,共11页Chunchen Wu Yanfang Zhang Ao Liang Xiaoxue Wu Yaqi Zhu Zhaoxuan Huang Jun Wang Yali Deng Lixian Pan Anbang Wang Fei Deng Jianbo Xia 
supported by the projects of National Virus Resource Center(NVRC-PY-03,E1YZ020501);Natural Science Foundation of Hubei Province(2022CFB564);Foundation of Hubei Provincial Health Commission(WJ2023M108);National Basic Science Data Sharing Platform(no.2018ZX10101004);National Basic Science Data Sharing Service Platform(no.NBSDC-DB-13);the International Cooperation Base of Hubei Province for Infection and Immunity;supported by Outstanding Medical Young Scholars of Hubei Province and Wuhan Young and Middle-aged Medical Backbone Talent Program.
Acute respiratory tract infections(ARTIs)are among the leading causes of morbidity and mortality in children worldwide.Human adenovirus(HAdV)infections are estimated to account for at least 5%of pediatric ARTIs.The ci...
关键词：Acute respiratory tract infection (ARTIs) Human adenovirus(HAdV) Viral isolates GENOTYPES Clinical characteristics PNEUMONIA 
Zika virus infections and associated risk factors among pregnant women in Gombe,Nigeria
《Virologica Sinica》2025年第1期61-70,共10页Oderinde Soji Bamidele Abdulbasi Bakoji Samaila Jackson Yaga Kunle Ijaya Bukar Mohammed Ismaila Yunusa Yuguda Marycelin M.Baba 
In-utero exposure to Zika virus(ZIKV)could lead to miscarriage,preterm birth and congenital Zika syndrome.This study aimed at estimating the burden of ZIKV and Dengue virus(DENV)infections among pregnant women in Boju...
关键词：Zika virus(ZIKV)infections Dengue virus(DENV)infections ELISA Neutralizing antibody(nAb) Pregnant women NIGERIA 
Discovery and characterization of a novel carlavirus in Ligularia jaluensis plants
《Virologica Sinica》2025年第1期71-79,共9页Shifang Fei Jiaping Yu Yali Zhou Yi Xie Li Xie Shuai Fu Jianxiang Wu 
financially supported by the Hainan Province Science and Technology Special Fund(No.ZDYF2022XDNY240);the National Key Research and Development Program of China(2022YFD1401200).
Ligularia jaluensis is an important medicinal and ornamental plant in China.However,the viruses capable of infecting Ligularia jaluensis remains unknown.Here,we identified a novel carlavirus,tentatively named ligulari...
关键词：Ligularia jaluensis Novel virus CARLAVIRUS Viral infectious clone Movement protein Pathogenicity factor 
Antigenic analysis of the influenza B virus hemagglutinin protein
《Virologica Sinica》2025年第1期80-91,共12页Mengyi Zhang Chaoying Yang Xi Wu Yifei Wang Lijie Wang Qianqian Cui Jincheng Tong Yimeng An Meina Cai Shishi Cheng Qi Jiang Yulin Wang Chenyan Zhao Youchun Wang Weijin Huang 
supported by a grant from the National Key R&D Program of China(No.2021YFC2301700);the Ministry of Science and Technology(China)of China(No.2021YFC2302500);the Establishment of a method for detecting neutralizing antibodies with pseudotyped viruses of China Pharmacopeia[grant number 2021S03].
Influenza B viruses(IBVs)primarily infect humans and are a common cause of respiratory infections in humans.Here,to systematically analyze the antigenicity of the IBVs Hemagglutinin(HA)protein,31 B/Victoria and 19 B/Y...
关键词：Influenza B virus(IBV) ANTIGENICITY Vaccine strains Pseudotyped viruses 
CRTC3 restricts SARS-CoV-2 replication and is antagonized by CREB
《Virologica Sinica》2025年第1期92-108,共17页Li Yang Xiao-Tao Zeng Rong-Hua Luo Ying Tang Si-Xue Ren Xin-Yan Long Xiang-Hui Fu Wan-Jiang Zhang Hai-Yan Ren Yong-Tang Zheng Wei Cheng 
supported by grants from the National Natural Science Foundation of China(32071236);the National Science Fund for Distinguished Young Scholars(32225001);the 1.3.5 Project for Disciplines Excellence of West China Hospital,Sichuan University(ZYGD23018);Key Science and Technology Research Projects in Key Areas of the Corps(2023AB053);the National Key Research and Development Program of China(2022YFC2303700);the Joint Project of Pengzhou People's Hospital with Southwest Medical University(2024PZXNYD02);Project funded by China Postdoctoral Science Foundation(2020M683304);Sichuan Science and Technology Support Project(2021YJ0502);Post-Doctor Research Project,West China Hospital,Sichuan University(2020HXBH082).
Virus-encoding RNA-dependent RNA polymerase(RdRp)is essential for genome replication and gene transcription of human coronaviruses(HCoVs),including severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).We previo...
关键词：Human coronaviruses(HCoVs) RNA-Dependent RNA polymerase (RdRp) CREB-regulated transcription coactivator 3(CRTC3) Virus replication Virus-host interaction Cyclic AMP response element-binding protein(CREB) 
Random forest algorithm reveals novel sites in HA protein that shift receptor binding preference of the H9N2 avian influenza virus
《Virologica Sinica》2025年第1期109-117,共9页Yuncong Yin Wen Li Rujian Chen Xiao Wang Yiting Chen Xinyuan Cui Xingbang Lu David M.Irwin Xuejuan Shen Yongyi Shen 
supported by the National Natural Science Foundation of China(32273037 and 32102636);the Guangdong Major Project of Basic and Applied Basic Research(2020B0301030007);Laboratory of Lingnan Modern Agriculture Project(NT2021007);the Guangdong Science and Technology Innovation Leading Talent Program(2019TX05N098);the 111 Center(D20008);the double first-class discipline promotion project(2023B10564003);the Department of Education of Guangdong Province(2019KZDXM004 and 2019KCXTD001).
A switch from avian-typeα-2,3 to human-typeα-2,6 receptors is an essential element for the initiation of a pandemic from an avian influenza virus.Some H9N2 viruses exhibit a preference for binding to human-typeα-2,...
关键词：H9N2 Hemagglutinin(HA) Receptor binding preference Random forest algorithm Host shift Interspecies transmission 
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