《Quantitative Biology》

作品数：230被引量：81H指数：4
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《Quantitative Biology》
主办单位：Higher Education Press,China;Tsinghua University,China
最新期次：2025年1期更多>>
发文主题：SINGLE-CELLDATACANCERJOURNALBIOINFORMATICS更多>>
发文领域：生物学医药卫生自动化与计算机技术理学更多>>
发文基金：国家自然科学基金中国博士后科学基金国家重点基础研究发展计划高等学校学科创新引智计划更多>>
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Physical mechanisms of human brain functions
《Quantitative Biology》2025年第1期1-27,共27页Zonghua Liu 
National Natural Science Foundation of China,Grant/Award Numbers:11835003,12175070;STI2030-Major Projects,Grant/Award Number:2021ZD0202600。
In recent years,exploring the physical mechanisms of brain functions has been a hot topic in the fields of nonlinear dynamics and complex networks,and many important achievements have been made,mainly based on the cha...
关键词：chimera states eigenmode analysis network synchronization remote firing propagation remote synchronization 
Stochastic thermodynamics for biological functions
《Quantitative Biology》2025年第1期29-47,共19页Yuansheng Cao Shiling Liang 
National Natural Science Foundation of China,Grant/Award Number:12374213;Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung,Grant/Award Number:200020_178763。
Living systems operate within physical constraints imposed by nonequilibrium thermodynamics.This review explores recent advancements in applying these principles to understand the fundamental limits of biological func...
关键词：biological functions physical constraints stochastic thermodynamics 
Mechanisms promoting biodiversity in ecosystems
《Quantitative Biology》2025年第1期49-61,共13页Ju Kang Yiyuan Niu Xin Wang 
National Natural Science Foundation of China,Grant/Award Numbers:12004443,12474207;Guangzhou Municipal Science and Technology Bureau,Grant/Award Number:202102020284。
Explaining biodiversity is the central focus in theoretical ecology.A significant obstacle arises from the competitive exclusion principle(CEP),which states that two species competing for the same type of resources ca...
关键词：BIODIVERSITY competitive exclusion principle paradox of the plankton 
Single-cell analyses reveal impaired type B spermatogonia differentiation and meiotic entry in C-Nap1-null testes
《Quantitative Biology》2025年第1期63-75,共13页Junlin Li Liheng Yang Liansheng Li Min Li Juntao Gao Li Yuan 
The Fundamental Research Funds for the Central Universities,Grant/Award Number:E1E43201X2;The Beijing Municipal Natural Science Foundation,Grant/Award Number:Z200021;The CAS Interdisciplinary Innovation Team,Grant/Award Number:JCTD-2020-04;The National Key Research and Development Program of China,Grant/Award Numbers:2021YFE0201100,2022YFA1103401;The National Natural Science Foundation of China,Grant/Award Number:31872839。
Sperm development is critical for male reproductive capability;any disruption during the process of spermatogenesis will result in male infertility.In this research,we used the C-Nap1 encoded by the gene of Cep250 kno...
关键词：C-Nap1 mouse testis single-cell RNA sequencing SPERMATOGENESIS 
Modeling telomere shortening process
《Quantitative Biology》2025年第1期77-87,共11页Panpan Han Yang Zhou Weihua Deng 
National Natural Science Foundation of China,Grant/Award Numbers:12225107,12071195;Major Science and Technology Projects in Gansu Province-Leading Talents in Science and Technology,Grant/Award Number:23ZDKA0005;Innovative Groups of Basic Research in Gansu Province,Grant/Award Number:22JR5RA391;Lanzhou Talent Work Special Fund。
Cell senescence has attracted much attention in the long history of human beings,and telomere shortening(TS)is one of the main concerns in the study of cell senescence.To reveal the microscopic mechanism of TS process...
关键词：AGING anomalous diffusion CTRW telomere shortening process 
Quantifying cell fate change under different stochastic gene activation frameworks
《Quantitative Biology》2025年第1期89-101,共13页Xinxin Chen Ying Sheng Liang Chen Moxun Tang Feng Jiao 
The National Natural Science Foundation of China,Grant/Award Numbers:12271118,12331017。
Gene transcription is a stochastic process characterized by fluctuations in mRNA levels of the same gene in isogenic cell populations.A central question in single-cell studies is how to map transcriptional variability...
关键词：cell fate change mRNA distribution statistical transcription threshold stochastic gene transcription transcription noise 
Self-organization of active plume lattice in bacterial bioconvection
《Quantitative Biology》2025年第1期103-112,共10页Siyu Liu Qihui Hou Daniel B.Kearns Yilin Wu 
Ministry of Science and Technology of China,Grant/Award Number:2020YFA0910700;Research Grants Council of Hong Kong SAR,Grant/Award Numbers:14307821,14307822,RFS2021-4S04;National Natural Science Foundation of China,Grant/Award Number:31971182;National Institutes of Health of United States,Grant/Award Number:NIH R35 GM131783。
Self-organized pattern formation is common in biological systems.Microbial populations can generate spatiotemporal patterns through various mechanisms,such as chemotaxis,quorum sensing,and mechanical interactions.When...
关键词：BIOCONVECTION CHEMOTAXIS microswimmers pattern formation SELF-ORGANIZATION 
An effective method for quantification,visualization,and analysis of 3D cell shape during early embryogenesis
《Quantitative Biology》2025年第1期113-126,共14页Zelin Li Zhaoke Huang Jianfeng Cao Guoye Guan Zhongying Zhao Hong Yan 
Embryogenesis is the most basic process in developmental biology.Effectively and simply quantifying cell shape is challenging for the complex and dynamic 3D embryonic cells.Traditional descriptors such as volume,surfa...
关键词：Caenorhabditis elegans(C.elegans) cell shape quantification eigen features(eigengrid eigenharmonic&eigenspectrum) lineage analysis morphological reproducibility spherical harmonics(SPHARM) 
AMHF-TP:Multifunctional therapeutic peptides prediction based on multi-granularity hierarchical features
《Quantitative Biology》2025年第1期127-141,共15页Shouheng Tuo YanLing Zhu Jiangkun Lin Jiewei Jiang 
National Natural Science Foundation of China,Grant/Award Number:62276210;Natural Science Basic Research Program of Shaanxi,Grant/Award Number:2022JM-380。
Multifunctional therapeutic peptides(MFTP)hold immense potential in diverse therapeutic contexts,yet their prediction and identification remain challenging due to the limitations of traditional methodologies,such as e...
关键词：deep learning hypergraph multifunctional therapeutic peptides multi-granularity hierarchical features 
Recent technology advancements in large-scale DNA assembly
《Quantitative Biology》2025年第1期143-151,共9页Jielin Li Li Cheng Yingxin Ma Yizhi Cai Junbiao Dai 
Elite Young Scientists Program of CAAS;National Natural Science Foundation of China,Grant/Award Numbers:32150025,31725002;Guangdong Provincial Key Laboratory of Synthetic Genomics,Grant/Award Number:2023B1212060054;Shenzhen Outstanding Talents Training Fund;Science and Technology Planning Project of Guangdong Province,Grant/Award Number:2022A0505090009;Bureau of International Cooperation,Chinese Academy of Sciences,Grant/Award Number:172644KYSB20180022;Innovation Program of Chinese Academy of Agricultural Sciences;Shenzhen Science and Technology Program,Grant/Award Number:KQTD20180413181837372;National Key Research and Development Program of China,Grant/Award Number:2022YFF1201800;Shenzhen Key Laboratory of Synthetic Genomics,Grant/Award Number:ZDSYS201802061806209。
The emergence and development of sequencing and DNA synthesis techniques have empowered us with the ability to read and write genomes,thereby enhancing our understanding and manipulation of biological processes.Over t...
关键词：saccharomyces cerevisiaewith synthetic yeast genome sequencing dna synthesis techniques understanding manipulation biological processesover sequencing techniques constructed all chromosomes read write genomesthereby artificially synthesized notablythe 
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