《Gastroenterology Report》

作品数：816被引量：1102H指数：12
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《Gastroenterology Report》
主办单位：中山大学
最新期次：2024年1期更多>>
发文主题：PATIENTSCOLORECTAL_CANCERULCERATIVE_COLITISENDOSCOPICCASE_REPORT更多>>
发文领域：医药卫生自动化与计算机技术文化科学经济管理更多>>
发文基金：国家自然科学基金广东省自然科学基金中国博士后科学基金国家重点基础研究发展计划更多>>
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A predictive model and rapid multi-dynamic algorithm developed based on tumor-stroma percentage in gastric cancer:a retrospective,observational study
《Gastroenterology Report》2024年第1期413-423,共11页Yitian Xu Yan Yang Feichi Cheng Zai Luo Yuan Zhang Pengshan Zhang Jiahui Qiu Zhengjun Qiu Chen Huang 
supported by the National Natural Science Foundation of China[grant number 82072662 and 82203751];Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support[grant number 2019142];Shanghai Three-year Action Plan to Promote Clinical Skills and Clinical Innovation in Municipal Hospitals[grant number SHDC2020CR4022];the 2021 Shanghai“Rising Stars of Medical Talent”Youth Development Program:Outstanding Youth Medical Talents。
Background:Tumor-stroma percentage(TSP)is a prognostic risk factor in numerous solid tumors.Despite this,the prognostic significance of TSP in gastric cancer(GC)remains underexplored.Through the development of a perso...
关键词：gastric cancer tumor-stroma percentage NOMOGRAM algorithm 
Cooperation of Wnt/β-catenin and Dll1-mediated Notch pathway in Lgr5-positive intestinal stem cells regulates the mucosal injury and repair in DSS-induced colitis mice model
《Gastroenterology Report》2024年第1期424-434,共11页Weijun Ou Weimin Xu Yaosheng Wang Zhebin Hua Wenjun Ding Long Cui Peng Du 
supported by the National Natural Science Foundation of China[No.82000481,81570474,and 82270549].
Background:Lgr5-positive cells located in the basal layer of crypts have self-regenerative and proliferative differentiation potentials of intestinal stem cells(ISCs),maintaining a balance of regeneration-repair in mu...
关键词：intestinal stem cell ulcerative colitis LGR5 Β-CATENIN NOTCH 
Phosphorylation of RelA/p65 Ser536 inhibits the progression and metastasis of hepatocellular carcinoma by mediating cytoplasmic retention of NF-κB p65
《Gastroenterology Report》2024年第1期435-448,共14页Wentao Zuo Haoyang Ma Jianghui Bi Tiaolan Li Yifeng Mo Shiyu Yu Jia Wang Beiqing Li Jinfeng Huang Yongwen Li Li Li 
funded by the College Students'Innovative Entrepreneurial Training Plan Program[no.202110601019].
Background:Intrahepatic and extrahepatic metastases contribute to the high recurrence rate and mortality of hepatocellular carcinoma(HCC).Constitutive activation of nuclear factor-κB(NF-κB)is a crucial feature of HC...
关键词：HCC NF-ΚB RelA/p65 Ser536 phosphorylation apoptosis METASTASIS 
TNFSF15 variant predicts disease progression in Chinese patients with Crohn’s disease
《Gastroenterology Report》2024年第1期449-457,共9页Qi Zhang Wei Wang Bingjie Xiang Dezheng Lin Jun Hu Junzhang Zhao Jue Lin Tao Liu Jun Deng Min Zhang Min Zhi 
supported by the Sun Yat-sen University Clinical Research 5010 Program[grant number 2014008];the National Natural Science Foundation of China[grant number 82270544];the Sixth Affiliated Hospital“Jie Bang Gua Shuai”Program[grant number 2022JBGS06];the Science and Technology Program of Guangzhou,China[grant number SL2022B03J00237];the Program of Guangdong Provincial Clinical Research Center for Digestive Diseases[grant number 2020B1111170004].
Background:The genetic variant of tumor necrosis factor superfamily member 15(TNFSF15)is associated with Crohn’s disease(CD)and the development of intestinal fibrosis and stricturing.We aimed to investigate its predi...
关键词：TNFSF15 Crohn’s disease SNP disease progression FIBROSIS 
Supplementation with probiotics,prebiotics,and synbiotics in patients with chronic functional constipation:a randomized,double-blind,placebo-controlled pilot clinical trial
《Gastroenterology Report》2024年第1期458-466,共9页Ana Terrén Lora Bruno F.Penadés Sara López Oliva Sari Arponen Gülsah Okutan Guerthy Melissa Sánchez Niño Ismael San Mauro Martín 
Background:Functional constipation includes a set of gastrointestinal symptoms unexplainable by an identifiable underlying physical cause or pathology.The prevalence of this condition is high and there is a need to de...
关键词：functional constipation PROBIOTICS PREBIOTICS gastrointestinal symptoms stool frequency stool consistency 
The benefit of surgery during systematic therapy for gastrointestinal stromal tumor liver metastasis:a SEER-based retrospective study
《Gastroenterology Report》2024年第1期467-473,共7页Bozhi Hu Yingjiang Ye Zhidong Gao 
funded by the Peking University People’s Hospital Scientific Research Development Funds(No.2147000814).
Background:The liver is the most common site of gastrointestinal stromal tumor(GIST)metastasis.Most patients who develop metastases gradually develop multiline drug resistance during long-term systematic treatment.We ...
关键词：GIST liver metastasis SEER SURGERY 
^(18)F-FAPI-42 PET/CT enhances the diagnostic efficacy for peritoneal metastasis of colorectal cancer and guides treatment decisions:an original retrospective study
《Gastroenterology Report》2024年第1期474-484,共11页Xuneng Zhang Rongqin Zhang Qingyang Zheng Zichuan He Bing Lan Yun Zhong Zhichao Huang Wei Fan Hui Wang Keli Yang Zhanwen Zhang Huaiming Wang 
the National Natural Science Foundation of China[grant no.82103084];the Dongguan Science and Technology of Social Development Program[grant no.20231800904303];Z.Z.has received grants from the National Natural Science Foundation of China[no.81901772];the Natural Science Foundation of Guangdong Province[nos 2019A1515011893,2023A1515011300];the State Key Laboratory of Pathogenesis,Prevention and Treatment of High Incidence Diseases in Central Asia&The First People’s Hospital of Kashi Fund[no.SKL-HIDCA-2020-KS2];H.W.has received grants from the Xinjiang Autonomous Region Technology Plan[grant no.2022E02125];The Sixth Affiliated Hospital of Sun Yat-Sen University Clinical Research-1010 Program:1010CG(2022)-08;K.Y.has received grants from the National Natural Science Foundation of China[grant no.82300619];the Science and Technology Projects in Guangzhou[grant no.2023A04J2245].
Background:Colorectal cancer is the third-most common type of cancer.When peritoneal metastasis(PM)develops,diagnosing metastatic lesions is difficult and the prognosis is poor.This study aimed to compare the value of...
关键词：colorectal cancer peritoneal metastasis ^(18)F-FAPI-42 PET/CT PCI 
Uncovering novel therapeutic clues for hypercoagulable active ulcerative colitis:novel findings from old data
《Gastroenterology Report》2024年第1期485-498,共14页Zhexuan Yu Danya Zhao Yusen Zhang Kezhan Shen Shisi Shao Xiaobo Chen Jianlong Shu Guanhua Li 
supported by the Zhejiang Chinese Medicine University Postgraduate Scientific Research Fund Project[grant number 2022YKJ02];Medical Scientific Research Foundation of Guangdong Province of China[grant number A2021433];Guangdong Basic and Applied Basic Research Foundation[grant numbers 2021A1515010280,2022A1515012170,and 2024A1515011242];China Postdoctoral Science Foundation[grant number 2023M730743];National Natural Science Foundation of China[grant number 82470422].
Background:Hypercoagulability has been shown to act as an important component of ulcerative colitis(UC)pathogenesis and disease activity,and is strongly correlated with the occurrence of venous thromboembolism(VTE).Th...
关键词：ulcerative colitis hypercoagulable state coagulation score model anti-TNF-αagents CXCL8 
Noninvasive tests for liver fibrosis in 2024:are there different scales for different diseases?
《Gastroenterology Report》2024年第1期499-513,共15页Jimmy Che-To Lai Lilian Yan Liang Grace Lai-Hung Wong 
supported by the General Research Fund-Research Grant Council(Project reference number:14106922)grant to Grace Wong.
Liver fibrosis is the common pathway from various chronic liver diseases and its progression leads to cirrhosis which carries a significant risk for the development of portal hypertension-related complications and hep...
关键词：FIB-4 liver fibrosis liver stiffness measurement noninvasive test vibration-controlled transient elastography 
Current epidemiology of chronic liver disease被引量：1
《Gastroenterology Report》2024年第1期588-597,共10页Richie Manikat Aijaz Ahmed Donghee Kim 
Chronic liver disease presents a significant global health burden,characterized by several etiologies,including metabolic dysfunction-associated steatotic liver disease(MASLD),alcohol-related liver disease(ALD),chroni...
关键词：NAFLD MASLD hepatitis B hepatitis C alcohol-related liver disease 
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