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Evaluation of albumin and lactate dehydrogenase in comparison with cytokeratin 19 fragments and neuronspecific enolase as diagnostic biomarkers for non-small cell lung cancer: 《iLABMED》2024年第4期227-237,共11页Xiaodong Feng Ning Yuan Wei Xu Yingying Ji Xiaoyan Yu Zhijun Zhang; Natural Science Foundation of Shandong Province,Grant/Award Number:ZR2020QH283;National Natural Science Foundation of China,Grant/Award Number:82002226;Tai'an City Science and Technology Development Plan Project,Grant/Award Numbers:2022NS332,2022NS212;Nursery Project of the Affiliated Tai'an City Central Hospital of Qingdao University,Grant/Award Number:2022MPM01。; Background:The diagnosis of non-small cell lung cancer(NSCLC)is a clinical issue that requires attention,and more practical and effective biomarkers need to be selected to assist in diagnosis.This study aimed to exami...; 关键词：ALBUMIN biomarkers lactate dehydrogenase non-small cell lung cancer receiver operating characteristic

Diagnostic value of exosomal N-glycan profiles for microvascular invasion in hepatocellular carcinoma: 《iLABMED》2024年第4期238-247,共10页Huijuan Feng Junping Ke Liping Zheng Chenjun Huang Lijuan Liu; Fuzhou“14th Five-Year”Clinical Key Specialty,Grant/Award Number:20220203;Natural Science Foundation of Fujian Province,Grant/Award Number:2020J011169。; Background:Microvascular invasion(MVI)was a critical high-risk factor for postoperative recurrence and adverse prognosis in patients with hepatocellular carcinoma(HCC),and there were no reliable non-invasive pre-opera...; 关键词：EXOSOME hepatocellular carcinoma microvascular invasion N-glycan profile

Machine learning model based on SERPING1,C1QB,and C1QC:A novel diagnostic approach for latent tuberculosis infection: 《iLABMED》2024年第4期248-265,共18页Linsheng Li Li Zhuang Ling Yang Zhaoyang Ye Ruizi Ni Yajing An Weiguo Zhao Wenping Gong; approved by The Ethics Committee of the Eighth Medical Center of PLA General Hospital(Approval Number:30920230825701232).; Background:Latent tuberculosis infection(LTBI)is a significant source of active tuberculosis(ATB),yet distinguishing between them is challenging because specific biomarkers are lacking.Methods:We analyzed four microar...; 关键词：diagnostic biomarkers immune microenvironment latent tuberculosis infection machine learning TRANSCRIPTOMICS

Rapid diagnosis of Mycoplasma pneumoniae and prediction of antibiotic resistance by nanopore adaptive sampling: 《iLABMED》2024年第4期266-276,共11页Yunke Sun Xiaonan Li Jiale He Lingguo Zhao Qingliang Chen Lei Lei Jun Chen Lin Zhong Guobao Li Yu Xia Yanmin Bao Yingdan Zhang Liang Yang; Science,Technology and Innovation Commission of Shenzhen Municipality,Grant/Award Number:JCYJ20210324115607021;Medical Scientific Research Foundation of Guangdong Province of China,Grant/Award Number:A2021416;National Natural Science Foundation of China,Grant/Award Numbers:32200155,32270196;Shenzhen Science and Technology Program,Grant/Award Numbers:JCYJ20220530163412029,JCYJ20220531093409021,JCYJ20230807153604009;National Key Research and Development Program of China,Grant/Award Number:2022YFC2304700。; Background:Microbial infections,particularly in children,require rapid and accurate diagnostics.It is difficult to differentiate pathogens from commensal organisms,and it is impossible to identify antibiotic resistanc...; 关键词：antimicrobial resistance Mycoplasma pneumonia nanopore adaptive sampling

Serum lipoprotein-associated phospholipase A2 activity in Chinese patients with systemic lupus erythematosus: 《iLABMED》2024年第4期277-285,共9页Jie Feng Kun Wang Yanhong Gao; Background:Few studies have explored the association between lipoprotein-associated phospholipase A2(Lp-PLA2)and systemic lupus erythematosus(SLE).However,most of these studies have investigated only European patient ...; 关键词：AUTOANTIBODIES clinical manifestations lipoprotein-associated phospholipase A2 systemic lupus erythematosus Disease Activity Index 2000 systemic lupus erythematosus

Effect of the Zushima patch combined with celecoxib on pain and inflammatory factor expression in knee osteoarthritis with cold-dampness obstruction: 《iLABMED》2024年第4期286-293,共8页Yumin Yang Lijun Sun Zhao Peng Xiumin Li Yan Chen; New Medical Emergency Requirement Demonstration,Grant/Award Number:LB2023B010100。; Background:Knee osteoarthritis(KOA)is a chronic degenerative joint dis-ease that frequently occurs in middle-aged and older individuals.Although celecoxib is a commonly used drug for the treatment of KOA,its efficacy ...; 关键词：CELECOXIB cold-dampness obstruction type inflammatory factor knee osteoarthritis Zushima patch

Dye-based recombinase-aided amplification assay with enhanced sensitivity and specificity: 《iLABMED》2024年第4期294-306,共13页Zijin Zhao Yanbo You Shaowei Hua Xinxin Shen Lingjun Li Xuejun Ma; National Key R&D Program of China,Grant/Award Number:2021YFC2301102;National Natural Science Foundation of China,Grant/Award Numbers:82202593,U23A20106。; Background:Fluorescent recombinase-aided amplification(RAA)assays are increasingly being used in the detection of a variety of pathogens and have the advantages of rapidity and simplicity and similar sensitivity and s...; 关键词：EvaGreen dye Listeria monocytogenes melt curve nucleotide analogs raw milk recombinase aided amplification SAMRS Staphylococcus aureus

Psychrobacter sanguinis infection in a pediatric patient with craniopharyngioma identified in a blood culture by 16S rRNA sequencing: 《iLABMED》2024年第4期323-326,共4页Jia Liu Xueping Cao Xiaoli Yang Lijie Song Feifei Duan Wei Zhang Yufei Wang; National Key research&Development Plan,Grant/Award Number:2018YFC1603705。; Psychrobacter species are gram-negative bacteria in the Moraxellaceae family.These bacteria are considered rare opportunistic human pathogens,and the infection sites include blood,cerebral spinal fluid,wounds,urine,th...; 关键词：16S rRNA postneurosurgical bacteremia Psychrobacter sanguinis

Clinicopathological and prognostic role of CEP55 expression in cancer patients:A meta‐analysis of 31 studies with 12,543 patients: 《iLABMED》2024年第4期327-340,共14页Jiangguo Zhang Xiaoyin Zhang; The 2022 Shenzhen Third People's Hospital Second Batch Medicine Research Project,Grant/Award Number:G2022129。; Background:Dysregulated expression of centrosomal protein 55(CEP55)has been detected in multiple types of cancers.However,the clinical value of CEP55 expression in cancer is controversial.The current meta-analysis qua...; 关键词：CANCER centrosomal protein 55 clinicopathological significance hazard ratio odds ratio prognostic significance

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