the National Natural Science Foundation of China(22325803,22077052,22277042,22107037,22177041,22207042);the China Postdoctoral Science Foundation(2021M691279);the National Key R&D Program of China(2023YFC2308000).
Treponema is a Gram-negative anaerobic bacterium,among which the pathogenic Treponema can cause various diseases,such as venereal syphilis(Treponema pallidum),yaws(Treponema carateum),and oral diseases(Treponema denti...
the Mega Project of China National Science Research for the 11th Five-year Plan(2008ZX10001-005);Natural Science Foundation of Jiangsu Province of China(BK20150121);National Natural Science Foundation of China(81601804,8177220);the Union Innovation Team Project of Chinese Academy of Medical Sciences(No.2016-I2M-3021).
Objective Although azithromycin is effective against Treponema pallidum (T.pallidum),the causative agent of syphilis,recent reports indicate that the prevalence of azithromycin resistance in China is very high,which m...
<正>Objective To trace changes in the transcript level of the Treponema pallidum(Tp)protein Tp0751 in skin lesions of a rabbit model of early syphilis.Methods Three New Zealand white rabbits were intracutaneously inje...
funded by the Danish Research Council for Technology and Production.
Digital dermatitis is a highly prevalent painful lesion affecting the feet in dairy cattle. Even though the pathogenesis has been subject of investigation since 1974, there is still a lack of knowledge about the sprea...
supported by the Foundation of Hunan Province Science and Technology Department,China (2010FJ2008,2012TT2006);the Natural Science Foundation of Hunan Province Science and Technology Department,China (11JJ9023);the Foundation of Hunan Province Education Department,China (11B107)
Syphilis is a multistage,sexually transmitted disease caused by the spirochete,Treponema pallidum(Tp).A significantly high incidence of syphilis has been reported in several countries,including China,and there is an u...
Syphilitic proctitis is a rare disease. It usually presents as proctitis, ulcer and neoplasm but lacks pathognomonic clinical symptoms. It is, therefore, difficult to diagnose and is occasionally treated inappropriate...
supported by the National Natural Science Foundation of China (Grant No. 30800996);the National Natural Science Foundation of Hunan Province (Grant No. 07ii3028)
The tissue destruction characteristic of syphilis infection may be caused by inflammation due to Treponema pallidum and the ensuing immune responses to the pathogen.T.pallidum membrane proteins are thought to be poten...
Objective: This study compared the performance of the immunochromatographic strip (ICS) to the Venereal Disease Research Laboratory (VDRL) test and Treponema pallidum haemagglutination assay (TPHA) at a primary...