TREPONEMA

作品数:17被引量:38H指数:2
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相关领域:医药卫生农业科学更多>>
相关作者:张龙黄淑伟武彩虹张朝云刘继勇更多>>
相关机构:中国石油中心医院复旦大学中日友好医院福建农林大学更多>>
相关期刊:《Science China(Life Sciences)》《Open Journal of Veterinary Medicine》《旅行医学科学》《World Journal of Gastrointestinal Pathophysiology》更多>>
相关基金:国家自然科学基金廊坊市科技局课题上海市科学技术委员会资助项目更多>>
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Chemical Synthesis of a Key Precursor Relevant to the Tetrasaccharide Repeating Unit from Treponema medium ATCC 700293
《Chinese Journal of Chemistry》2024年第14期1615-1622,共8页Wenbin Sun Guangzong Tian Meiru Ding Chunjun Qin Xiaopeng Zou Jing Hu Jian Yin 
the National Natural Science Foundation of China(22325803,22077052,22277042,22107037,22177041,22207042);the China Postdoctoral Science Foundation(2021M691279);the National Key R&D Program of China(2023YFC2308000).
Treponema is a Gram-negative anaerobic bacterium,among which the pathogenic Treponema can cause various diseases,such as venereal syphilis(Treponema pallidum),yaws(Treponema carateum),and oral diseases(Treponema denti...
关键词:Glycosylation Total synthesis Treponema medium ATCC 700293 Tetrasaccharide precursor Protecting group OLIGOSACCHARIDES Regioselectivity Neighboring-group effects 
Relationship between the high frequency of 23S rRNA point mutations in Treponema pallidum and low serological response rate to azithromycin treatment in China被引量:2
《International Journal of Dermatology and Venereology》2019年第1期6-14,共9页Rui-Li Zhang Qian-Qiu Wang Zhi-Ju Zheng Guo-Jun Liang Li-Jia Yang Li-Gang Yang Dong-Nu Pei Shao-Chun Lin 
the Mega Project of China National Science Research for the 11th Five-year Plan(2008ZX10001-005);Natural Science Foundation of Jiangsu Province of China(BK20150121);National Natural Science Foundation of China(81601804,8177220);the Union Innovation Team Project of Chinese Academy of Medical Sciences(No.2016-I2M-3021).
Objective Although azithromycin is effective against Treponema pallidum (T.pallidum),the causative agent of syphilis,recent reports indicate that the prevalence of azithromycin resistance in China is very high,which m...
关键词:SYPHILIS AZITHROMYCIN Mutation SEROLOGICAL response TREPONEMA PALLIDUM 
口腔螺旋体新种Treponema putidum的多位点序列分析
《微生物学免疫学进展》2017年第2期17-23,共7页莫思溯 鲍炜 李鸣宇 
上海市科委项目(16140903300)
目的应用多位点序列分析方法鉴定一种与齿垢密螺旋体(Treponema denticola,T.denticola)近似的新种口腔螺旋体细菌Treponema putidum(T.putidum)。方法选用16S r RNA,rec A和pyr H基因构建5种T.putidum菌株和7种T.denticola菌株以及其...
关键词:口腔螺旋体 TREPONEMA putidum 多位点序列分析 
Transcript levels of the Treponema pallidum protein Tp0751 in skin lesions of a rabbit model of early syphilis
《China Medical Abstracts(Internal Medicine)》2016年第1期19-19,共1页柯吴坚 
<正>Objective To trace changes in the transcript level of the Treponema pallidum(Tp)protein Tp0751 in skin lesions of a rabbit model of early syphilis.Methods Three New Zealand white rabbits were intracutaneously inje...
关键词:TREPONEMA PALLIDUM RABBIT Nichols injected TRANSCRIPT Zealand SUSPENSIONS dynamically creased 
新生儿血清梅毒抗体酶联免疫吸附试验检测假阳性结果分析被引量:2
《山西医药杂志》2015年第5期589-590,共2页张龙 黄淑伟 张朝云 刘继勇 武彩虹 
河北省廊坊市科技局项目(2013013020C)
梅毒是临床常见性传播疾病之一,其病原体为梅毒螺旋体(Treponema Pallidum),又叫苍白螺旋体[1]。我国20世纪60年代已基本消灭梅毒,但近年来梅毒的发病率有上升趋势[2]。临床表现多样,病情复杂,已成为重要的临床医学问题。血清梅毒抗...
关键词:梅毒抗体 新生儿血清 假阳性结果 苍白螺旋体 梅毒螺旋体 TREPONEMA 酶联免疫吸附 性传播疾病 临床症状 灰区 
A Study into Digital Dermatitis Transmission and Bacterial Associated Pathological Changes Involved in the Disease
《Open Journal of Veterinary Medicine》2013年第2期192-198,共7页N.Capion M.Boye C.Ekstrom K.Dupont T.K.Jensen 
funded by the Danish Research Council for Technology and Production.
Digital dermatitis is a highly prevalent painful lesion affecting the feet in dairy cattle. Even though the pathogenesis has been subject of investigation since 1974, there is still a lack of knowledge about the sprea...
关键词:Digital Dermatitis Treponema spp. HISTOPATHOLOGY Infection Dynamics 
Assessment of the immune responses to Treponema pallidum Gpd DNA vaccine adjuvanted with IL-2 and chitosan nanoparticles before and after Treponema pallidum challenge in rabbits被引量:10
《Science China(Life Sciences)》2013年第2期174-180,共7页ZHAO FeiJun ZHANG XiaoHong LIU ShuangQuan ZENG TieBing YU Jian GU WeiMing ZHANG YueJun CHEN Xi WU YiMou 
supported by the Foundation of Hunan Province Science and Technology Department,China (2010FJ2008,2012TT2006);the Natural Science Foundation of Hunan Province Science and Technology Department,China (11JJ9023);the Foundation of Hunan Province Education Department,China (11B107)
Syphilis is a multistage,sexually transmitted disease caused by the spirochete,Treponema pallidum(Tp).A significantly high incidence of syphilis has been reported in several countries,including China,and there is an u...
关键词:Treponema pailidum (Tp) membrane protein GPD CS IL-2 nucleic acid vaccine 
Syphilitic proctitis mimicking rectal cancer:A case report
《World Journal of Gastrointestinal Pathophysiology》2010年第3期112-114,共3页Wen-Tao Zhao, Jing Liu, Yu-Ying Li 
Syphilitic proctitis is a rare disease. It usually presents as proctitis, ulcer and neoplasm but lacks pathognomonic clinical symptoms. It is, therefore, difficult to diagnose and is occasionally treated inappropriate...
关键词:SYPHILIS RECTUM PROCTITIS RECTAL cancer TREPONEMA PALLIDUM 
Production of proinflammatory cytokines in the human THP-1 monocyte cell line following induction by Tp0751,a recombinant protein of Treponema pallidum被引量:28
《Science China(Life Sciences)》2010年第2期229-233,共5页LIU ShuangQuan1,2,WANG ShiPing1,WU YiMou3,ZHAO FeiJun3,ZENG TieBing3,ZHANG YueJun3,ZHANG QiuGui2 & GAO DongMei1 1 Department of Parasitology,Xiangya School of Medicine,Central South University,Changsha 410078 ,China 2 The First Affiliated Hospital,University of South China,Hengyan 421001,China 3 Department of Microbiology and Immunology,University of South China,Hengyan 421001,China 
supported by the National Natural Science Foundation of China (Grant No. 30800996);the National Natural Science Foundation of Hunan Province (Grant No. 07ii3028)
The tissue destruction characteristic of syphilis infection may be caused by inflammation due to Treponema pallidum and the ensuing immune responses to the pathogen.T.pallidum membrane proteins are thought to be poten...
关键词:TREPONEMA PALLIDUM Tp0751 nuclear factor ΚB PROINFLAMMATORY cytokines 
Evaluation of the immunochromatographic strip test for the rapid diagnosis of antenatal syphilis in women in Eldoret,Kenya
《Journal of Nanjing Medical University》2009年第5期317-321,共5页Lydia B. Nyamwamu Michael M. Gicheru Rekha R. Sharma lbert Kimutai Willy K.Tonui Peter Kamau Ngure 
Objective: This study compared the performance of the immunochromatographic strip (ICS) to the Venereal Disease Research Laboratory (VDRL) test and Treponema pallidum haemagglutination assay (TPHA) at a primary...
关键词:SYPHILIS Immunochromatographic strip test Venereal Disease Research Laboratory Treponema Pa//idum haemagglutinationAssay SPECIFICITY Sensitivity Positive Predictive Value Negative Predictive Value antenatal syphilis 
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