supported by the National Natural Science Foundation of China(32373062);the Natural Science Foundation of Shandong Province(ZR2023MC144);Funds of Shandong Province Modern Agricultural Technology System Innovation Team Program(SDAIT-21-10).
Background Deoxynivalenol(DON)is a mycotoxin that severely pollutes feed ingredients,and methods for reducing DON toxicity have become a significant research direction.Chlorogenic acid(CGA)is an active polyphenol foun...
funded by FEDER/Ministerio de Ciencia,Innovación y Universidades Agencia Estatal de Investigación/Project(PID2020-119729GB-100,REF/AEI/10.13039/501100011033)(to EP);a predoctoral fellowship from the Spanish Ministry of Universities(FPU)and Amigos de la Universidad de Navarra(to NSS);“Programa MRR Investigo 2023”(to MGB and MMD)。
Sirtuin 2 is a member of the sirtuin family nicotinamide adenine dinucleotide(NAD~+)-dependent deacetylases, known for its regulatory role in different processes, including inflammation. In this context, sirtuin 2 has...
National Key Research and Development Program of Traditional Chinese Medicine Modernization Research Key Project:Innovative Research and Application based on the Core Etiology and Pathogenesis of Different Diseases and the Same Treatment Plan based on"Blood Stasis,Toxin and Depression"(2019YFC1708700,2019YFC1708701);National Natural Science Foundation of China Key Project:Biological Basic Research on Gastric Cancer-Carcinoma Transformation and Intervention by Removing Blood Stasis and Detoxification Based on the Pathogenesis Theory of Blood Stasis and Toxin Interaction(82030119);General project of the National Natural Science Foundation of China:Study on the Mechanism of Tanshinone Combined with Arsenic Trioxide Stasis and Poison to Regulate Macrophage Polarization and Improve the Inflammatory Microenvironment of Liver Cancer(81874455);Key R&D Program of Zhejiang Province:Research on Innovative Traditional Chinese Medicine Drugs-preclinical Research on Anti-lung Cancer of Diterpenoid Tanshinone(2019C03072);Zhejiang Province Traditional Chinese Medicine Modernization Project:Study on the Diagnosis and Treatment Program of Damp-heat Accumulation Type Colorectal Cancer Based on Correlation Analysis of Intestinal Microbiota-Traditional Chinese Medicine Syndrome Type(2020ZX005);Key Research Projects of Zhejiang Traditional Chinese Medicine Science and Technology Program:Research on Quantitative Characterization of Preparation Process and Quality Standard Control Specification of Traditional Chinese Medicine Paste(Gao Zi Ji)(2019ZZ006);National Natural Science Foundation of China General Project:Study on the Molecular Mechanism of Actinidia Chinensis Polysaccharide Interfering with Epithelial Mesenchymal Transformation in Gastric Cancer by Inhibiting Nuclear Factor-κB Pathway(81273904);The Research Project of Zhejiang Chinese Medical University:Study on the Mechanism of the Effective Components of Tengli Root Regulating Tumor-associated Fibroblasts to Improve the Tumor Microenvironment and Prevent the Metastasis of Ga
OBJECTIVE:To investigate the mechanisms of the effect of Actinidia chinensis polysaccharide(ACPS)on the invasion and metastasis of gastric cancer cells.METHODS:BGC-823-Luc gastric cancer cells stably transfected with ...